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2013
The "mesenchymal stem cells (MSCs)" are cells adherent in the bone marrow, which can be isolated to induce differentiation. In contrast to the "embryonic stem cells" whose goal is to develop a new organism, the "MSC adult stem cells" can participate in tissue growth and repair throughout postnatal life.
Minh Ngoc, Duong +2 more
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The "mesenchymal stem cells (MSCs)" are cells adherent in the bone marrow, which can be isolated to induce differentiation. In contrast to the "embryonic stem cells" whose goal is to develop a new organism, the "MSC adult stem cells" can participate in tissue growth and repair throughout postnatal life.
Minh Ngoc, Duong +2 more
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Regulatory Cells in the Bone Marrow
1976Regulation of the immune system has been attributed primarily to thymus-derived T cells (1,2). Here we present evidence that suppression can be mediated by another cell type, found in the bone marrow, that is neither a T cell nor a macrophage. Others have also shown that bone marrow-derived (B) cell suppression can inhibit both humoral and cell ...
S, Adler, S K, Singhal, E E, Sercarz
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Osteogenesis in transplants of bone marrow cells
Development, 1966ABSTRACT After heterotopic (e.g. subcutaneous) transplantation of bone marrow, haemopoiesis in the graft ceases; reticular tissue develops instead, and later bone is formed (Denis, 1958). The result can be achieved by grafting either free pieces of bone marrow or those placed in diffusion chambers (Petrakova, Tolmacheva & ...
Friedenstein, A J +2 more
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Cellular Immunology, 1974
Abstract Mouse bone marrow (BM) contains cells capable of responding in vitro to the T cell mitogens, phytohemagglutinin (PHA) and concanavalin A (Con A). These responses are less vigorous than those of spleen cells. The optimal mitogen concentrations for BM cells are different from those for spleen cells; BM cells require twice as much ...
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Abstract Mouse bone marrow (BM) contains cells capable of responding in vitro to the T cell mitogens, phytohemagglutinin (PHA) and concanavalin A (Con A). These responses are less vigorous than those of spleen cells. The optimal mitogen concentrations for BM cells are different from those for spleen cells; BM cells require twice as much ...
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Bone marrow-derived cells and hypertension
Expert Review of Cardiovascular Therapy, 2010Although it is clear that inadequate perfusion underlies most of the organ dysfunction accounting for hypertension-related adverse outcomes, our understanding of the pathophysiologic mechanisms is still evolving. The most important approaches to improving vascular health include reducing injury to the vessel wall and enhancing mechanisms to repair ...
Ki E, Park, Carl J, Pepine
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Bone Reconstruction with Bone Marrow Stromal Cells
2006Bone marrow stromal/stem cells (BMSCs) are multipotent adult stem cells and have become the important cell source for cell therapy and engineered tissue repair. Their osteogenic differentiation potential has been well characterized in many in vitro studies.
Wei, Liu, Lei, Cui, Yilin, Cao
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Importance of bone marrow cell dose in bone marrow transplantation
Clinical Transplantation, 1992The importance of the size of the infused marrow cell dose (MCD) was investigated in 274 patients undergoing allogeneic BMT between 1975 and 1990. Among those, 65 had acute myelogenous leukemia (AML), 79 acute lymphoblastic leukemia (ALL), 58 chronic myelogenous leukemia (CML) and 25 severe aplastic anemia (SAA).
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Regulation of Constitutive Bone Marrow Cell Proliferation by Bone Marrow Suppressor Cells
International Archives of Allergy and Applied Immunology, 2009Bone marrow (BM) cells have previously been shown to suppress specific immune responses of cells from peripheral lymphoid organs. The present report describes a suppressor cell present in normal rabbit BM, which regulated the constitutive proliferation of other BM cells.
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Bone Marrow-Derived Dendritic Cells
2013While much is understood about dendritic cells and their role in the immune system, the study of these cells is critical to gain a more complete understanding of their function. Dendritic cell isolation from mouse body tissues can be difficult and the number of cells isolated small.
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Bone marrow mesenchymal stem cells
Journal of Cellular Biochemistry, 2009AbstractFollowing the identification of bone marrow multipotent cells that could adhere to plastic and differentiate along numerous mesenchymal lineages in vitro, a considerable effort has been invested in characterizing and expanding these cells, which are now called “mesenchymal stem cells” (MSCs), in vitro. Over the years, numerous lines of evidence
Masanobu, Ohishi, Ernestina, Schipani
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