Results 41 to 50 of about 943,151 (365)
The role of cyclic nucleotide on fetal and neonantal erythropoiesis [PDF]
For the purpose to reveal the changes in stimulatory effect of dibutyryl-cyclic- AMP on erythropoiesis during ontogenetic development, the author studied syntheses of DNA, RNA and protein of erythroid cells in fetal liver, neonatal and adult bone marrows
Tada, Hiroshi
core +1 more source
Simultaneous administration of adjuvant donor bone marrow in pancreas transplant recipients [PDF]
Objective: The effect of donor bone marrow was evaluated for its potentially favorable effect in the authors' simultaneous pancreas/kidney transplant program.
Abdul S. Rao+35 more
core +2 more sources
Patients who have undergone autologous stem cell transplantation are subsequently more susceptible to chemotherapy-induced bone marrow toxicity. In the present study, bone marrow primitive progenitor cells were examined one year after autologous stem ...
Carolien M. Woolthuis+5 more
doaj +1 more source
Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis. [PDF]
Myeloablative preconditioning using irradiation is the most commonly used technique to generate rodents having chimeric bone marrow, employed for the study of bone marrow-derived cell accumulation in the healthy and diseased central nervous system ...
Coral-Ann B Lewis+6 more
doaj +1 more source
Induction of hemopoiesis in rat embryonic bone transplanted into adult subcutaneous connective tissue [PDF]
Five pairs of immature, non-hemopoietic femur and tibia from 17-day-old gestating female rat fetuses, whose sex was determined by chromosomal analysis of liver cells, were transplanted into subcutaneous tissues of adult male rats. The original bones were
Hsueh, Chao Liang
core +1 more source
BackgroundIn recent years, chimeric antigen receptor (CAR)-T cell therapy has achieved tremendous efficacy in relapsed/refractory multiple myeloma (R/R MM).
Lingling Yin+54 more
doaj +1 more source
Background Lenalidomide improves erythropoiesis in patients with low/intermediate-1 risk myelodysplastic syndrome and interstitial deletion of the long arm of chromosome 5 [del(5q)].
Maria Ximeri+15 more
doaj +1 more source
Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment. [PDF]
The myeloma bone marrow microenvironment promotes proliferation of malignant plasma cells and resistance to therapy. Activation of JAK/STAT signaling is thought to be a central component of these microenvironment-induced phenotypes.
Aftab, Blake T+13 more
core +2 more sources
Identity of Gli1+ cells in the bone marrow [PDF]
Bone marrow fibrosis is a critical component of primary myelofibrosis in which normal bone marrow tissue and blood-forming cells are gradually replaced with scar tissue. The specific cellular and molecular mechanisms that cause bone marrow fibrosis are not understood.
Pedro H.D.M. Prazeres+13 more
openaire +3 more sources
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source