Results 41 to 50 of about 970,786 (391)
A clinical trial combining donor bone marrow infusion and heart transplantation: intermediate-term results. [PDF]
, 2000 BACKGROUND: Donor chimerism (the presence of donor cells of bone marrow origin) is present for years after transplantation in recipients of solid organs. In lung recipients, chimerism is associated with a lower incidence of chronic rejection.
Fung, JJ +8 more
core +1 more source
GATA2 regulates differentiation of bone marrow-derived mesenchymal stem cells
Haematologica, 2014 The bone marrow microenvironment comprises multiple cell niches derived from bone marrow mesenchymal stem cells. However, the molecular mechanism of bone marrow mesenchymal stem cell differentiation is poorly understood. The transcription factor GATA2 is
Mayumi Kamata +12 more
doaj +1 more source
Evidence for engraftment of human bone marrow cells in non-lethally irradiated baboons [PDF]
, 1997 Background. Prior to organ harvesting, an attempt was made to modulate the donor's immune responses against prospective xenogeneic recipients by infusion of 'recipient-type' bone marrow. Methods.
Fontes, P +7 more
core +1 more source
Cell Transplantation, 2000 Bone marrow contains various primitive cells that are thought to secrete several angiogenic growth factors and may also differentiate into endothelial cells. The present study was conducted to investigate the possibility that bone marrow cells could be a
Kimikazu Hamano M.D. +5 more
doaj +1 more source
Effect of enkephalins on bone marrow cells
Biomedicine & Pharmacotherapy, 1992 Mouse bone marrow cells were incubated with methionine- or leucine-enkephalin (10(-15)-10(-6) M) before seeding into soft agar cultures. In marrow samples harvested at different times, enkephalins decreased GM colony count on average by 30-40%. In individual experiments, however, the same concentration of enkephalins caused even stimulation, or at ...
L Krizanac-Bengez +3 more
openaire +3 more sources
Identity of Gli1+ cells in the bone marrow [PDF]
Experimental Hematology, 2017 Bone marrow fibrosis is a critical component of primary myelofibrosis in which normal bone marrow tissue and blood-forming cells are gradually replaced with scar tissue. The specific cellular and molecular mechanisms that cause bone marrow fibrosis are not understood.
Pedro H.D.M. Prazeres +13 more
openaire +3 more sources
Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment. [PDF]
, 2018 The myeloma bone marrow microenvironment promotes proliferation of malignant plasma cells and resistance to therapy. Activation of JAK/STAT signaling is thought to be a central component of these microenvironment-induced phenotypes.
Aftab, Blake T +13 more
core +2 more sources
Haematologica, 2013 Patients who have undergone autologous stem cell transplantation are subsequently more susceptible to chemotherapy-induced bone marrow toxicity. In the present study, bone marrow primitive progenitor cells were examined one year after autologous stem ...
Carolien M. Woolthuis +5 more
doaj +1 more source
Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis. [PDF]
PLoS ONE, 2013 Myeloablative preconditioning using irradiation is the most commonly used technique to generate rodents having chimeric bone marrow, employed for the study of bone marrow-derived cell accumulation in the healthy and diseased central nervous system ...
Coral-Ann B Lewis +6 more
doaj +1 more source
Characterization of Bone Marrow Stromal Cells [PDF]
Hematology, 1999 (1999). Characterization of Bone Marrow Stromal Cells. Hematology: Vol. 4, No. 3, pp. 237-237.
Joel S. Greenberger, Armand Keating
openaire +3 more sources