Results 61 to 70 of about 213,033 (265)

Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass. [PDF]

, 2012
Aging reduces the number of mesenchymal stem cells (MSCs) that can differentiate into osteoblasts in the bone marrow, which leads to impairment of osteogenesis.
Guan, Min, Jia, Junjing, Lam, Kit S, Lane, Nancy E, Liu, Ruiwu, Meng, Liping, Nolta, Jan, Panganiban, Brian, Ritchie, Robert O, Shahnazari, Mohammad, Yao, Wei, Zhou, Ping   +11 more
core   +1 more source

Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering. [PDF]

, 2019
Prenatal stem cell-based regenerative therapies have progressed substantially and have been demonstrated as effective treatment options for fetal diseases that were previously deemed untreatable. Due to immunoregulatory properties, self-renewal capacity,
Farmer, Diana L, Guo, Fuzheng, Hao, Dake, He, Chuanchao, Lankford, Lee, Ma, Bowen, Reynaga, Lizette, Wang, Aijun   +7 more
core   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

12 hours after cerebral ischemia is the optimal time for bone marrow mesenchymal stem cell transplantation

Neural Regeneration Research, 2015
Cell therapy using stem cell transplantation against cerebral ischemia has been reported. However, it remains controversial regarding the optimal time for cell transplantation and the transplantation route.
Seyed Mojtaba Hosseini, Mohammad Farahmandnia, Zahra Razi, Somayeh Delavarifar, Benafsheh Shakibajahromi   +4 more
doaj   +1 more source

Characterization of mesenchymal stem cells of "no-options" patients with critical limb ischemia treated by autologous bone marrow mononuclear cells. [PDF]

PLoS ONE, 2013
BackgroundApplication of autologous bone marrow mononuclear cells to "no option" patients with advanced critical limb ischemia (CLI) prevented major limb amputation in 73% patients during the 6-month follow-up. We examined which properties of bone marrow
Cestmir Altaner, Veronika Altanerova, Marina Cihova, Lubica Hunakova, Katarina Kaiserova, Andrej Klepanec, Ivan Vulev, Juraj Madaric   +7 more
doaj   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Emilin-2 is a component of bone marrow extracellular matrix regulating mesenchymal stem cell differentiation and hematopoietic progenitors

Stem Cell Research & Therapy, 2022
Background Dissection of mechanisms involved in the regulation of bone marrow microenvironment through cell–cell and cell–matrix contacts is essential for the detailed understanding of processes underlying bone marrow activities both under physiological ...
Francesco Da Ros, Luca Persano, Dario Bizzotto, Mariagrazia Michieli, Paola Braghetta, Mario Mazzucato, Paolo Bonaldo   +6 more
doaj   +1 more source

The Floor‐Ceiling‐Chip, or 2 × 2D = Pseudo‐3D—Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell‐Adhesive Protein Micropatterns

Advanced Healthcare Materials, EarlyView.
Here, we present a novel 3D cell patterning and culture platform. The “Floor‐Ceiling‐Chip” (FC‐Chip) consists of two opposing track‐etched membranes, creating a pseudo‐3D microenvironment for the cells in between. By providing the membranes with micropatterned cell‐adhesive islands of varying geometries and sizes, the FC‐Chip enables control over cell ...
Urandelger Tuvshindorj, Francesca Giacomini, Esra Güben Kaçmaz, Tim ten Brink, Lorenzo Moroni, Zeinab Tahmasebi Birgani, Clemens van Blitterswijk, Pamela Habibović, Stefan Giselbrecht, Jan de Boer, Roman Truckenmüller   +10 more
wiley   +1 more source

Optimization and Comparison of the PolyFect Gene Delivery Method in Three Different Kinds of Mesenchymal Stem Cell Types [PDF]

Cell Journal, 2010
Objective: The aim of this study was optimization of the PolyFect gene delivery methodof pcDNA3.1 expression vector transfected with the mouse pdx-1 gene in three differentkinds of mesenchymal stem cells and Hepa cells as well as comparison of ...
Pezhman Fard-Esfahani, Neda Memari, Mehdi Kadivar   +2 more
doaj  

Intraovarian injection of autologous human mesenchymal stem cells increases estrogen production and reduces menopausal symptoms in women with premature ovarian failure: two case reports and a review of the literature

Journal of Medical Case Reports, 2020
Background Premature ovarian failure is a relatively common condition that affects 1–3% of adult women. Premature ovarian failure occurs when there is loss of ovarian function in women younger than 40 years of age.
Prosper Igboeli, Abdeljabar El Andaloussi, Ujalla Sheikh, Hajra Takala, Amro ElSharoud, Ashley McHugh, Larisa Gavrilova-Jordan, Steven Levy, Ayman Al-Hendy   +8 more
doaj   +1 more source