Results 151 to 160 of about 1,205,734 (289)

Prostatic carcinoma metastasis in bone marrow of sternum (human)

, 2007
Stain: Hematoxylin and eosin. Survey (A) and detail (B) of a prostate carcinoma metastasized to the bone marrow, (sternum aspiration). Clusters of tumour cells; clearly foreign to the marrow.
Poels, Lambert G.
core  

Lanthanum Carbonate Nanosheets Based Colloidal Hydrogel for Modulating Innate & Adaptive Tumor Immunotherapy by Augmented Cellular Pyroptosis

Advanced Science, EarlyView.
The Gela/decitabine/La2(CO3)3 colloidal (GDLC) hydrogel developed here could reverse the epigenetic silencing of the GSDME gene by the synergistic interaction between DAC and La3+, while concurrently activating caspase‐3, thus facilitating pyroptosis induction under the tumor microenvironment.
Yang Hong, Haitao Wu, Weitao Wang, Xuan Zhang, Qian Chen, Yaoyu Hu, Zhengbao Zha   +6 more
wiley   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

The Role of the Bone Marrow Microenvironment in the Pathogenesis of Acute Myeloid Leukemia. [PDF]

Biomedicines
Gottardi M, De Marchi F, Ciotti G, Basso M, Raimondi V, Ciminale V, Simonetti G, Ghetti M, Di Liddo R, De Marchi R, Abouzeid IA, Sperotto A.   +11 more
europepmc   +1 more source

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

Advanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li, Yingjie Yu, Tianchang He, Xiaoyan Fang, Wenhua Yang, Luying Zhou, Hao Fan, Guimei Lin, Daniel Crespy, Katharina Landfester, Junfeng Zhang, Shuai Jiang   +11 more
wiley   +1 more source

Drug Resistance in Multiple Myeloma: Tumor-Intrinsic Mechanisms and the Bone Marrow Microenvironment. [PDF]

Cell Biochem Funct
Chen Y, Huang W, Tang M, Wang X.
europepmc   +1 more source

Contamination with osteoclasts of a bone marrow puncture (human)

, 2007
Stain: May-Grnwald-Giemsa (MGG). In the procedure for preparing a bone marrow smear from a sternum puncture osteoclasts are frequently found in the bone marrow smears.
Poels, Lambert G.
core  

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Inflammatory bone marrow microenvironment impairs the therapeutic effect of daratumumab-lenalidomide in multiple myeloma. [PDF]

Biomark Res
Cheng W, Gaggero S, Hasan Bou Issa L, Ouelkdite A, Escure G, Cozzani A, Njosse Tchantchou Y, Carlier N, Wauquier E, Decool G, Tilmont R, Podvin B, Leprohon M, Shekarkar M, Fléchon L, Kasprowicz A, Groux-Degroote S, Moreaux J, Arnulf B, Corre J, Villenet C, Martinet L, Leleu X, Figeac M, Facon T, Jin W, Mitra S, Manier S.   +27 more
europepmc   +1 more source

Survey and detail of bone marrow section (human)

, 2007
Stain: modified hematoxylin and eosin (A, B). The bone marrow consists of bone trabecles or crests (1) covered with osteoclasts and osteoblasts. Between the trabecles bone marrow parenchym (2) consisting of progenitor cells, reticular cells and fat cells
Poels, Lambert G.
core