Results 241 to 250 of about 1,205,734 (289)

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

Senescence in the bone marrow microenvironment: A driver in development of therapy-related myeloid neoplasms. [PDF]

J Bone Oncol
Guilatco AJ, Shah MV, Weivoda MM.
europepmc   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Immune infiltration-related genes regulate the progression of AML by invading the bone marrow microenvironment. [PDF]

Front Immunol
Yu S, Jiang J.
europepmc   +1 more source

Radiomics analysis of thoracic vertebral bone marrow microenvironment changes before bone metastasis of breast cancer based on chest CT. [PDF]

J Bone Oncol
Zhu HN, Guo YF, Lin Y, Sun ZC, Zhu X, Li Y.   +5 more
europepmc   +1 more source

Instructive interaction between myelodysplastic hematopoiesis and the bone marrow microenvironment at the single-cell level. [PDF]

Blood Neoplasia
Jann JC, Schmitt N, Streuer A, Xu Q, Riabov V, Altrock E, Weimer N, Nowak V, Obländer J, Palme I, Göl M, Demmerle M, Rapp F, Siegel F, Steiner L, Ghazal M, Duda A, Haselmann V, Darwich A, Jawhar A, Jawhar M, Metzgeroth G, Hofmann WK, Nowak D.   +23 more
europepmc   +1 more source

Age and dose dependent changes to the bone and bone marrow microenvironment after cytotoxic conditioning with busulfan. [PDF]

Front Cell Dev Biol
Abbasizadeh N, Burns CS, Verrinder R, Ghazali F, Seyedhassantehrani N, Spencer JA.   +5 more
europepmc   +1 more source

Pathways to therapy resistance: The sheltering effect of the bone marrow microenvironment to multiple myeloma cells. [PDF]

Heliyon
Bhowmick K, von Suskil M, Al-Odat OS, Elbezanti WO, Jonnalagadda SC, Budak-Alpdogan T, Pandey MK.   +6 more
europepmc   +1 more source

Engineering the bone marrow microenvironment

openaire   +2 more sources

Heterogeneous stiffness of the bone marrow microenvironment regulates the fate decision of haematopoietic stem and progenitor cells. [PDF]

Cell Prolif
Shi G, Chang Z, Zhang P, Zou X, Zheng X, Liu X, Yan J, Xu H, Tian Z, Zhang N, Cui N, Sun L, Xu G, Yang H.   +13 more
europepmc   +1 more source