Results 91 to 100 of about 483,425 (231)

Frequency of BCR-ABL Fusion Transcript in Iranian Patients with Chronic Myeloid Leukemia

International Journal of Hematology-Oncology and Stem Cell Research, 2005
Introduction: Reverse transcriptase-polymerase chain reaction (RT-PCR) assay is a useful tool for the detection of fusion transcript resulting from specific chromosomal translocation of the leukemia cells.
M Yaghmaie, S.H Ghaffari, K Alimoghaddam, A Ghavamzadeh, S.A Mousavi, M Irvani, B Bahar, E Bibordi, M Jahani   +8 more
doaj  

Modeling the Multiple Myeloma Vicious Cycle: Signaling Across the Bone Marrow Microenvironment [PDF]

arXiv, 2015
Multiple myeloma is a plasma cell cancer that leads to a dysregulated bone remodeling process. We present a partial differential equation model describing the dynamics of bone remodeling with the presence of myeloma tumor cells. The model explicitly takes into account the roles of osteoclasts, osteoblasts, precursor cells, stromal cells, osteocytes ...
arxiv  

Bone marrow transplantation for thalassaemia [PDF]

Journal of Internal Medicine, 1997
For all patients with a histocompatibiliy antigen (HLA) identical donor we are actually using two protocols to whom the patient is assigned. This is based on which class the patients belongs to at the time of bone‐marrow transplant and is independent from the patient's age.
openaire   +3 more sources

Alternative donor transplantation after reduced intensity conditioning: results of parallel phase 2 trials using partially HLA-mismatched related bone marrow or unrelated double umbilical cord blood grafts.

Blood, 2011
The Blood and Marrow Transplant Clinical Trials Network conducted 2 parallel multicenter phase 2 trials for individuals with leukemia or lymphoma and no suitable related donor.
C. Brunstein, E. Fuchs, S. Carter, C. Karanes, L. Costa, Juan Wu, S. Devine, J. Wingard, O. Aljitawi, C. Cutler, M. Jagasia, K. Ballen, M. Eapen, P. O'Donnell   +13 more
semanticscholar   +1 more source

A synthetic three-dimensional niche system facilitates generation of functional hematopoietic cells from human-induced pluripotent stem cells

Journal of Hematology & Oncology, 2016
Background The efficient generation of hematopoietic stem cells (HSCs) from human-induced pluripotent stem cells (iPSCs) holds great promise in personalized transplantation therapies.
Yulin Xu, Wei Shan, Xia Li, Binsheng Wang, Senquan Liu, Yebo Wang, Yan Long, Ruxiu Tie, Limengmeng Wang, Shuyang Cai, Hao Zhang, Yu Lin, Mingming Zhang, Weiyan Zheng, Yi Luo, Xiaohong Yu, Jiing-Kuan Yee, Junfeng Ji, He Huang   +18 more
doaj   +1 more source

Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees.

Osteoarthritis and Cartilage, 2002
OBJECTIVE There is no widely accepted method to repair articular cartilage defects. Bone marrow mesenchymal cells have the potential to differentiate into bone, cartilage, fat and muscle.
S. Wakitani, K. Imoto, Tetsuya Yamamoto, M. Saito, N. Murata, M. Yoneda   +5 more
semanticscholar   +1 more source

HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair

Journal of Experimental & Clinical Cancer Research, 2018
Background With the development of novel therapeutic agents, the survival of multiple myeloma (MM) patients has much improved. However, the disease is incurable due to drug resistance. Previous studies have found that high-mobility group box 1 (HMGB1) is
Xing Guo, Donghua He, Enfan Zhang, Jing Chen, Qingxiao Chen, Yi Li, Li Yang, Yang Yang, Yi Zhao, Gang Wang, Jingsong He, Zhen Cai   +11 more
doaj   +1 more source

Analysis of Unobserved Heterogeneity via Accelerated Failure Time Models Under Bayesian and Classical Approaches [PDF]

arXiv, 2017
This paper deals with unobserved heterogeneity in the survival dataset through Accelerated Failure Time (AFT) models under both frameworks--Bayesian and classical. The Bayesian approach of dealing with unobserved heterogeneity has recently been discussed in Vallejos and Steel (2017), where mixture models are used to diminish the effect that anomalous ...
arxiv  

Endothelial and Complement Activation As Predictors of Survival in Adult Allogeneic Hematopoietic Cell Transplantation

HemaSphere, 2021
Eleni Gavriilaki, Ioanna Sakellari, Thomas Chatzikonstantinou, Despina Mallouri, Ioannis Batsis, Anna Vardi, Zoi Bousiou, Eudoxia-Evaggelia Koravou, Marianna Masmanidou, Tasoula Touloumenidou, Apostolia Papalexandri, Anastasia Athanasiadou, Evangelia Yannaki, Achilles Anagnostopoulos   +13 more
doaj   +1 more source

A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: delayed transplantation for low-risk myelodysplasia is associated with improved outcome.

Blood, 2004
Bone marrow transplantation (BMT) can cure myelodysplastic syndrome (MDS), although transplantation carries significant risks of morbidity and mortality.
C. Cutler, Stephanie J. Lee, P. Greenberg, H. Deeg, W. Pérez, C. Anasetti, B. Bolwell, M. Cairo, R. Gale, J. Klein, H. Lazarus, J. Liesveld, P. McCarthy, G. Milone, J. D. Rizzo, K. Schultz, M. Trigg, A. Keating, D. Weisdorf, J. Antin, M. Horowitz   +20 more
semanticscholar   +1 more source