Results 151 to 160 of about 255,505 (337)

Diagnostic value of magnetic resonance imaging and bone scan to diagnose the vertebral metastases

مجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: The vertebra is the most common site of bone metastases. Diagnosis of metastases particularly in the early stages can improve patients’ prognosis and therapy.
Farshchian N, Farshchian N, Ashraf Falah A   +2 more
doaj  

Bone metastases in biliary cancers: A multicenter retrospective survey

, 2018
Daniele Santini, Giovanni Brandi, G. Aprile, Marco Russano, Stefano Cereda, Francesco Leone, Sara Lonardi, Lorenzo Fornaro, Mario Scartozzi, Nicola Silvestris, Sandro Barni, Francesco Pantano, Bruno Vincenzi, Andrea Palloni, Giorgio Frega, Mariaelena Casagrande, L. Ferrari, Vincenzo Dadduzio, Rossana Intini, Roberto Filippi, Enrico Vasile, Caterina Vivaldi, Luca Faloppi, Oronzo Brunetti, Michele Reni, Massimo Aglietta, Giuseppe Tonini   +26 more
openalex   +1 more source

Pain Flare Following Radiotherapy for Painful Bone Metastases: A Joint Effort of Three Cancer Centres to Determine the Incidence [PDF]

, 2007
Amanda Hird, S. Hadi, Andrew Loblaw, Rebecca Wong, J. Wu, Edward Chow   +5 more
openalex   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

Pharmacologic management of bone-related complications and bone metastases in postmenopausal women with hormone receptor-positive breast cancer

Breast Cancer: Targets and Therapy, 2016
Denise A Yardley1,2 1Sarah Cannon Research Institute, Nashville, TN, USA; 2Tennessee Oncology, Nashville, TN, USA Abstract: There is a high risk for bone loss and skeletal-related events, including bone metastases, in postmenopausal women with hormone ...
Yardley DA
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Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Samarium-153-ethylene diamine tetramethylene phosphonate, a beta-emitting bone-targeted radiopharmaceutical, useful for patients with osteoblastic bone metastases

Cancer Management and Research, 2013
John Longo,1 Stephen Lutz,2 Candice Johnstone1 1Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, USA; 2Department of Radiation Oncology, Blanchard Valley Regional Cancer Center, Findlay, OH, USA Abstract: Bone metastases are
Longo J, Lutz S, Johnstone C
doaj  

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

Cancer Response Criteria and Bone Metastases: RECIST 1.1, MDA and PERCIST

Journal of Cancer, 2010
Response criteria represent the standard by which the efficacy of therapeutic agents is determined in cancer trials. The most widely used criteria are based on the anatomic measurement of solid tumors.
Colleen M. Costelloe, Hubert H. Chuang, John E. Madewell, Naoto T. Ueno
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