Results 141 to 150 of about 183,117 (350)
Identification of bone and liver metastases from breast cancer by measurement of plasma alkaline phosphatase isoenzyme activity. [PDF]
, 1987 Philip Mayne +4 more
openalex +1 more source
Advanced Science, EarlyView.We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang +11 more
wiley +1 more source
Bone Metastases from Gastric Cancer Resembling Paget’s Disease: A Case Report [PDF]
, 2022 Hisaki Aiba +9 more
openalex +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Advanced Science, EarlyView.We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin +10 more
wiley +1 more source
Tartrate-Resistant Acid Phosphatase Isoform 5B (TRACP 5B) As Serum Marker of Bone Metastases From Non-Small Cell Lung Cancer (NSCLC) and Breast Cancer. Preliminary Results [PDF]
, 2015 Franco Lumachi +4 more
openalex +1 more source
The Surgical Treatment of Vertebral Metastases: a Multicentric Study
, 1998 The Surgical Treatment of Vertebral Metastases: a Multicentric ...
GIUDICE V. +7 more
core
Palliative treatment: selective arterial embolisation for bone metastases.
, 2012 Treatment options in patients with bone metastases are mostly aimed at palliation. The goals of treatment in these patients are pain control, prevention and treatment of fractures, maintenance of independence and prevention of tumor progression, and ...
Rossi G +4 more
core +1 more source
Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids
Advanced Science, EarlyView.Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan +19 more
wiley +1 more source