Results 21 to 30 of about 2,167,273 (278)

The Role of TGF-β in Bone Metastases

Biomolecules, 2021
Complications associated with advanced cancer are a major clinical challenge and, if associated with bone metastases, worsen the prognosis and compromise the survival of the patients.
T. Trivedi, G. Pagnotti, T. Guise, K. Mohammad   +3 more
semanticscholar   +1 more source

Prospective comparison of the diagnostic accuracy of 18F-FDG PET/MRI, MRI, CT, and bone scintigraphy for the detection of bone metastases in the initial staging of primary breast cancer patients

European Radiology, 2021
To compare the diagnostic performance of [18F]FDG PET/MRI, MRI, CT, and bone scintigraphy for the detection of bone metastases in the initial staging of primary breast cancer patients.
N. Bruckmann, J. Kirchner, L. Umutlu, W. Fendler, R. Seifert, K. Herrmann, Ann-Kathrin Bittner, O. Hoffmann, S. Mohrmann, C. Antke, L. Schimmöller, M. Ingenwerth, K. Breuckmann, A. Stang, C. Buchbender, G. Antoch, L. Sawicki   +16 more
semanticscholar   +1 more source

Bone Metastases, Skeletal-Related Events, and Survival in Patients With Metastatic Non-Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitors.

The Journal of the National Comprehensive Cancer Network, 2021
BACKGROUND Bone metastases and skeletal-related events (SREs) are a frequent cause of morbidity in patients with metastatic non-small cell lung cancer (mNSCLC).
A. Qin, Songzhu Zhao, A. Miah, Lai Wei, Sandip H. Patel, A. Johns, M. Grogan, E. Bertino, K. He, P. Shields, G. Kalemkerian, S. Gadgeel, N. Ramnath, B. Schneider, K. Hassan, N. Szerlip, Z. Chopra, S. Journey, J. Waninger, Daniel J. Spakowicz, D. Carbone, C. Presley, G. Otterson, Michael D. Green, D. Owen   +24 more
semanticscholar   +1 more source

Bone metastases in non-small cell lung cancer: a narrative review

Journal of Thoracic Disease, 2021
Background and Objective Bone metastases are common in patients with non-small cell lung cancer (NSCLC) and remain a significant source of morbidity, mortality, and diminished quality of life, despite the considerable progress made in the overall ...
Brendan Knapp, S. Devarakonda, R. Govindan   +2 more
semanticscholar   +1 more source

Immune Checkpoint Inhibitor Therapy for Bone Metastases: Specific Microenvironment and Current Situation

Journal of Immunological Research, 2021
The treatment of bone metastases is a thorny issue. Immunotherapy may be one of the few hopes for patients with unresectable bone metastases. Immune checkpoint inhibitors are the most commonly used immunotherapy drugs currently.
Chang Liu, Miao Wang, Chang Xu, Bo Li, Juxiang Chen, Jianchun Chen, Zhiwei Wang   +6 more
semanticscholar   +1 more source

EpCAM expression in lymph node and bone metastases of prostate carcinoma: A pilot study [PDF]

, 2016
There is an urgent need for new imaging modalities in prostate carcinoma staging. A non-invasive modality that can assess lymph node and bone metastases simultaneously is preferred.
Campos, A.K. (Anna K.), Hoving, H.D. (Hilde D.), Jong, I.J. (Igle) de, Leenders, G.J.H.L. (Geert), Rosati, S. (Stefano)   +4 more
core   +7 more sources

Association of RANKL and EGFR gene expression with bone metastases in patients with metastatic non-small cell lung cancer

Frontiers in Oncology, 2023
IntroductionBone metastases are frequent in patients with non-small cell lung cancer (NSCLC). The receptor activator of Nuclear Factor κB (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) pathway is important in bone metastases development.
Anita J.W.M. Brouns, Anita J.W.M. Brouns, Anita J.W.M. Brouns, Lizza E.L. Hendriks, Lizza E.L. Hendriks, Iris J. Robbesom-van den Berge, Annemariek J.H.M. Driessen, Guido M.J.M. Roemen, Britt L.J. van Herpen, Zoë Dekkers, Bas Heitzer, Daphne J.G. Leunissen, Laura Moonen, Ragnar Lunde, Marcel Westenend, Marjolein van Driel, Ernst-Jan M. Speel, Anne-Marie C. Dingemans, Anne-Marie C. Dingemans, Anne-Marie C. Dingemans   +19 more
doaj   +1 more source

Dynamics of Bone Trap-5b Level in Patients with Bone Metastases of Renal Cell Cancer at Combined Treatment [PDF]

, 2017
The objective of this study was to determine the sensitivity of tartrate-resistant acid phosphatase (Bone TRAP-5b) for early detection of bone metastases (BM) and to investigate the efficacy of bisphosphonates (BF) (zolendronic acid-ZA) in prevention of ...
Boichuk, S. (Serhiy), Diedkov, A. (Anatoliy), Kostiuk, V. (Viktor), Ostafiychuk, V. (Vasyliy)   +3 more
core   +2 more sources

Incidence of patients with bone metastases at diagnosis of solid tumors in adults: a large population-based study

Annals of Translational Medicine, 2020
Background Bones are one of the most common metastatic sites for solid malignancies. Bone metastases can significantly increase mortality and decrease the quality of life of cancer patients.
Jin-Feng Huang, Jianfei Shen, Xiao Li, R. Rengan, N. Silvestris, Minqi Wang, L. Derosa, Xuan-Qi Zheng, A. Belli, Xiao-Lei Zhang, Y. Li, A. Wu   +11 more
semanticscholar   +1 more source

Tumor-targeting Salmonella typhimurium A1-R inhibits human prostate cancer experimental bone metastasis in mouse models. [PDF]

, 2015
Bone metastasis is a frequent occurrence in prostate cancer patients and often is lethal. Zoledronic acid (ZOL) is often used for bone metastasis with limited efficacy.
Bouvet, Michael, Hoffman, Robert M, Hu, Cameron, Matsumoto, Yasunori, Miwa, Shinji, Nakanishi, Hayao, Toneri, Makoto, Yano, Shuya, Zhang, Yong, Zhao, Ming   +9 more
core   +3 more sources