Results 21 to 30 of about 255,505 (337)

Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: Metastasis to the bone is one clinically important features of prostate cancer (PCa). Current diagnostic methods cannot predict metastatic PCa at a curable stage of the disease.
Elin Thysell   +10 more
doaj   +1 more source

Pain and analgesic use associated with skeletal-related events in patients with advanced cancer and bone metastases [PDF]

open access: yes, 2015
PURPOSE: Bone metastases secondary to solid tumors increase the risk of skeletal-related events (SREs), including the occurrence of pathological fracture (PF), radiation to bone (RB), surgery to bone (SB), and spinal cord compression (SCC).
A Hussain   +55 more
core   +2 more sources

SURVIVAL IMPACT OF SKELETAL METASTASIS ON BONE SCINTIGRAPHY IN PATIENTS WITH GERM CELL TUMOURS

open access: yesJournal of Cancer and Allied Specialties, 2016
Objective: Our aim was to determine the frequency of skeletal metastasis in germ cell tumours (GCT) at baseline and relapse on conventional technetium-99m methylene diphosphonate (Tc-99m MDP) whole body bone scan (bone scan) and to evaluate the effect of
Maimoona Siddique   +2 more
doaj   +1 more source

Incidence, prevalence, and outcomes of systemic malignancy with bone metastases

open access: yesJournal of Orthopaedic Surgery, 2020
Purpose: Evidence on the incidence, prevalence, and outcomes of bone metastases among patients with systemic malignancy is limited. This study aimed to evaluate it using the Surveillance, Epidemiology, and End Results (SEER) database.
Wenli Jiang   +5 more
doaj   +1 more source

Characteristics and Treatment of Bone Metastases in 322 Cases Non-small Cell Lung Cancer: A Retrospective Study

open access: yesChinese Journal of Lung Cancer, 2014
Background and objective Bone metastases are the most common metastases of the non-small cell lung cancer (NSCLC). It can lead to bone ache and pathology fracture, deteriorate the quality of life.
Qingzhi GUO   +7 more
doaj   +1 more source

Recent Advances in Nanomedicine for the Diagnosis and Treatment of Prostate Cancer Bone Metastasis

open access: yesMolecules, 2021
Patients with advanced prostate cancer can develop painful and debilitating bone metastases. Currently available interventions for prostate cancer bone metastases, including chemotherapy, bisphosphonates, and radiopharmaceuticals, are only palliative ...
Daniel E. Hagaman   +4 more
doaj   +1 more source

Sites of synchronous distant metastases and prognosis in prostate cancer patients with bone metastases at initial diagnosis: a population-based study of 16,643 patients

open access: yesClinical and Translational Medicine, 2019
Background Bone is a preferential site for prostate cancer (PCa) metastasis. However, sites of synchronous distant metastases in PCa patients with bone metastases at initial diagnosis and their impacts on prognosis are still unclear, limiting our ability
Feng Zhao   +8 more
doaj   +1 more source

Serum calcium, alkaline phosphotase and hemoglobin as risk factors for bone metastases in bladder cancer. [PDF]

open access: yesPLoS ONE, 2017
Early detection of bone metastases is helpful for the treatment of bladder cancer (BC). In this study, we investigated the potential risk factors for bone metastasis in newly diagnosed patients with BC.
Ping Huang   +7 more
doaj   +1 more source

NPNT promotes early-stage bone metastases in breast cancer by regulation of the osteogenic niche

open access: yesJournal of Bone Oncology, 2018
Patients with breast cancer are often afflicted by bone metastases, while the establishment and growth of bone metastases depend on interaction between cancer cells and the host environment.
Dongsheng Wang   +9 more
doaj   +1 more source

Bibliometric analysis of the global research development of bone metastases in prostate cancer: A 22-year study

open access: yesFrontiers in Oncology, 2022
BackgroundProstate cancer (PCa) is the second most diagnosed cancer in men. Most PCa-related deaths result from metastatic disease. Metastases occur most often in the bones (90%).
Yongming Chen   +16 more
doaj   +1 more source

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