Results 241 to 250 of about 379,930 (351)

Effect of enzalutamide on anticoagulant therapy with edoxaban in patients with prostate cancer

British Journal of Clinical Pharmacology, EarlyView.
Aims Treatment with enzalutamide in prostate cancer is challenging due to its high potential for drug–drug interactions, particularly in the typically older population of patients with frequent comorbidities treated with multiple drugs, such as anticoagulants.
Catharina J. P. Op 't Hoog, Niven Mehra, Anouk van Kleef, Diederik M. Somford, Inge M. van Oort, Alex L. T. Imholz, Paul Hamberg, Nielka P. van Erp, Emmy Boerrigter   +8 more
wiley   +1 more source

Global trends in breast cancer bone metastasis research (2009-2024): a bibliometric and visual analysis of hotspots and future directions. [PDF]

Discov Oncol
Wang Z, Zuo Y, Chen X, Pan Y, He Z, Xu S, Li Y, Li P, Wei X, Xu Y, Feng Y, Tian Z.   +11 more
europepmc   +1 more source

Mitigating subtherapeutic cabozantinib exposure after prior mitotane therapy in adrenocortical carcinoma: Pharmacological boosting with cobicistat

British Journal of Clinical Pharmacology, EarlyView.
Mitotane is an adrenolytic drug with cytotoxic effects, registered for the treatment of advanced adrenocortical carcinoma (ACC), a rare but aggressive tumour type with a poor prognosis despite treatment. Recently, the oral multi‐kinase inhibitor cabozantinib has shown promising results as a potential second‐line treatment option.
Annemieke M. Peters van Ton, Nielka P. van Erp, Annenienke C. van de Ven, Janneke E. W. Walraven, Loek A. W. de Jong   +4 more
wiley   +1 more source

The diagnostic value of inflammatory markers in bone metastasis of prostate cancer at initial prostate biopsy. [PDF]

Front Oncol
Chen X, Li Y, Chen Z, Xie G, Yin H, Li G.   +5 more
europepmc   +1 more source

Dynamic Immune Cell Composition, Phenotypes, and Signaling in an Engineered Metastatic Niche

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In breast cancer patients, metastasis is the stage of disease where prognosis significantly worsens. However, the timing at which metastasis initiates and the location of metastatic lesions in an organ are stochastic, limiting the timely identification of disease and the administration of treatments.
Rebecca S. Pereles, Jyotirmoy Roy, Michael D. Brooks, Max S. Wicha, Jacqueline S. Jeruss, Lonnie D. Shea, Sophia M. Orbach   +6 more
wiley   +1 more source

Radiofrequency Ablation and Cryoablation in Treating Painful Bone Metastasis: A Comprehensive Systematic Review and Separate Single-Arm Meta-analysis. [PDF]

Orthop Rev (Pavia)
Alaqeel M, Alnajres A, Mulia Y, Alanezi M, Alsenani S, Alqazlan F, Aljarba M, Albishi W, Alshaygy I, Alaseem A.   +9 more
europepmc   +1 more source

Multimodal imaging in an experimental rat model for brain metastasis [PDF]

, 2017
De Meulenaere, Valerie, De Wever, Olivier, Deblaere, Karel, Decrock, Elke, Descamps, Benedicte, Neyt, Sara, Vandeghinste, Bert, Vanhove, Christian   +7 more
core   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Doxorubicin induces bone loss and modifies multiple cell populations <i>in vivo</i> - Implications for modelling of bone metastasis. [PDF]

J Bone Oncol
Aydin VK, Saleh L, Ottewell PD, Holen I.
europepmc   +1 more source