Results 241 to 250 of about 381,513 (352)

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

Animal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou, Huajun Wang, Hao Guo, Dongbin Luo, Xiaofei Zheng, Simin Luo   +5 more
wiley   +1 more source

Vibration-Mediated Recovery of Irradiated Osteocytes and Their Regulatory Role in Breast Cancer Bone Metastasis. [PDF]

Adv Healthc Mater
Song X, Seaman K, Sassi A, Lin CY, Chu T, Wang L, Sun Y, You L.   +7 more
europepmc   +1 more source

Biocompatibility and healing patterns in experimentally induced canine tibial fractures using Pedicle screw‐Rod external fixation

Animal Models and Experimental Medicine, EarlyView.
This study demonstrates that using a Pedicle screw‐Rod configuration for the external fixation of non‐articular tibial osteotomy aligns well with the principles of biological osteosynthesis, resulting in secondary bone healing characterized by callus formation and neovascularization.
Mohammad Mahdi Gooran, Ramin Mazaheri‐Khameneh, Seyed Mohammad Hashemi‐Asl, Rahim Hobbenaghi   +3 more
wiley   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

YTHDF3 promotes breast cancer osteolytic bone metastasis by enhancing the translation of ZEB1 and SMAD5. [PDF]

Oncogenesis
Xu L, Yu Q, Peihang X, Li K, Wang B, Shao Y, Cheng M, Huang W, Yao Q, Feng X, Song S, Wang S, Yan W.   +12 more
europepmc   +1 more source

Supplementary figure 10 from Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis

Japneet Kaur, Manish Adhikari, Hayley M. Sabol, Aric Anloague, Sharmin Khan, Noriyoshi Kurihara, Marta Diaz‐delCastillo, Christina Møller Andreasen, C. Lowry Barnes, Jeffrey B. Stambough, Michela Palmieri, Olivia Reyes‐Castro, Jennifer Zarrer, Hanna Taipaleenmäki, Elena Ambrogini, Maria Almeida, Charles A. O’Brien, Intawat Nookaew, Jesús Delgado‐Calle   +18 more
openalex   +1 more source

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Bone metastasis in colorectal cancer: Pathophysiology, prognostic factors, survival outcomes, and treatment strategies - A comprehensive review. [PDF]

J Bone Oncol
Hatoum L, Murr RE, Assi A, Mohanna R, Sebaaly A, Kourie HR.   +5 more
europepmc   +1 more source

Figure S3 from PRODH2-Mediated Metabolism in the Bone Microenvironment Promotes Breast Cancer Metastasis

Hui Gong, Yixuan Li, Wen Yang, Zishan Xie, Jiahao Hu, Peihang Li, Rou Xu, Yifan Li, Tianyu Tao, Riqing Li, Shuguang Liu, Yefeng Zhu, Libing Song, Lishan Fang   +13 more
openalex   +1 more source

Protective effects of miR-24-2-5p in early stages of breast cancer bone metastasis [PDF]

Margherita Puppo, Martine Croset, Davide Ceresa, Manoj K. Valluru, Victor Gabriel Canuas Landero, Monserrat Hernandez Guadarrama, Michele Iuliani, Francesco Pantano, Penelope D. Ottewell, Philippe Clézardin   +9 more
openalex   +1 more source