Dynamic Immune Cell Composition, Phenotypes, and Signaling in an Engineered Metastatic Niche
ABSTRACT In breast cancer patients, metastasis is the stage of disease where prognosis significantly worsens. However, the timing at which metastasis initiates and the location of metastatic lesions in an organ are stochastic, limiting the timely identification of disease and the administration of treatments.
Rebecca S. Pereles +6 more
wiley +1 more source
The diagnostic value of inflammatory markers in bone metastasis of prostate cancer at initial prostate biopsy. [PDF]
Chen X +5 more
europepmc +1 more source
Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang +6 more
wiley +1 more source
Radiofrequency Ablation and Cryoablation in Treating Painful Bone Metastasis: A Comprehensive Systematic Review and Separate Single-Arm Meta-analysis. [PDF]
Alaqeel M +9 more
europepmc +1 more source
Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan +8 more
wiley +1 more source
Doxorubicin induces bone loss and modifies multiple cell populations <i>in vivo</i> - Implications for modelling of bone metastasis. [PDF]
Aydin VK, Saleh L, Ottewell PD, Holen I.
europepmc +1 more source
Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma +9 more
wiley +1 more source
LINC00917 Promotes Bone Metastasis of Breast Cancer by Targeting the miR-491-5p/FOXP4 Axis. [PDF]
Qu X +7 more
europepmc +1 more source

