Results 81 to 90 of about 264,729 (304)
Breast Cancer Associated Metastasis is Significantly Increased in a Model of Autoimmune Arthritis
, 2008 Chronic inflammation is known to play a role in cancer initiation, promotion,and metastasis. However, the mechanism by which inflammation promotes metastasis is still unclear.
Latha Pathangey +3 more
core
Circulating Tumour Cells in the Prediction of Bone Metastasis
Bone is the most common organ for the development of metastases in many primary tumours, including those of the breast, prostate and lung. In most cases, bone metastasis is incurable, and treatment is predominantly palliative.
Aria Kaiyuan Sun +3 more
core +1 more source
[Bone metastasis in prostate cancer] [PDF]
, 2012 Bone metastasis and skeletal complications have a devastating impact on the quality of life and are a major cause of morbidity in prostate cancer patients.
Moltzahn, F, Thalmann, G N
core +1 more source
Advanced Healthcare Materials, EarlyView.A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni +7 more
wiley +1 more source
Can PSA Predict Bone Metastasis amongst Newly Diagnosed Prostate Cancer Patients?
The Annals of African Surgery, 2018 Background: The decision as to when a bone scan is necessary in the staging of prostate cancer is controversial with different studies giving varying recommendations on the same subject.
D. Ojuka, MBChB, MMed, Surgery +2 more
doaj
Cancer Communications, 2019 Bone metastasis is the leading cause of death in prostate cancer patients, for which there is currently no effective treatment. Since the bone microenvironment plays an important role in this process, attentions have been directed to the interactions ...
Xiangyu Zhang
doaj +1 more source
The Effects of TGF-β Signaling on Cancer Cells and Cancer Stem Cells in the Bone Microenvironment [PDF]
, 2019 Background: Transforming growth factor-β (TGF-β) plays a key role in bone metastasis formation; we hypothesized the possible involvement of TGF-β in the induction of cancer stem cells (CSCs) in the bone microenvironment (micro-E), which may be ...
Lami, Kris +11 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină +2 more
wiley +1 more source
BMC Cancer, 2020 Background The prognosis is very poor for lung cancer patients with bone metastasis. Unfortunately, a suitable method has yet to become available for the early diagnosis of bone metastasis in lung cancer patients. The present work describes an attempt to
Xiaoyan Teng +4 more
doaj +1 more source
Bone-Specific Enhancement of Antibody Therapy for Breast Cancer Metastasis to Bone
, 2022 Despite the rapid evolution of therapeutic antibodies, their clinical efficacy in the treatment of bone tumors is hampered due to the inadequate pharmacokinetics and poor bone tissue accessibility of these large macromolecules.
Ling Wu (151826) +10 more
core +1 more source