Results 61 to 70 of about 205,288 (347)

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

Advanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna, Katarina Gugujonovic, Manuela Schiek, Alessandro Bellapianta, Paul Werginz, Amelie Ziller, Markus Clark Scharber, Ahmad Salti, Matthias Bolz, Mihai Irimia‐Vladu, Günther Zeck   +10 more
wiley   +1 more source

The role of skeletal tissue remodeling markers in the patho-genesis of implant-associated inflammation after primary knee arthroplasty [PDF]

Саратовский научно-медицинский журнал, 2018
Aim: to reveal certain mechanisms of the pathogenesis of implant-associated inflammation by the level of resorption and bone tissue genesis markers in patients who underwent primary knee arthroplasty. Material and Methods.
Galashina Е.А., Bondarenko A.S., Ulyanov V.Yu., Klimov S.S.   +3 more
doaj  

Noggin depletion in adipocytes promotes obesity in mice. [PDF]

, 2019
ObjectiveObesity has increased to pandemic levels and enhanced understanding of adipose regulation is required for new treatment strategies. Although bone morphogenetic proteins (BMPs) influence adipogenesis, the effect of BMP antagonists such as Noggin ...
Blázquez-Medela, Ana M, Boström, Kristina I, Fogelman, Alan M, Guo, Yina, Jumabay, Medet, Lusis, Aldons J, Rajbhandari, Prashant, Reue, Karen, Sallam, Tamer, Tontonoz, Peter, Vergnes, Laurent, Wu, Xiuju, Yao, Jiayi, Yao, Yucheng, Zhang, Li   +14 more
core   +1 more source

Effects of ADMA upon gene expression: An insight into the pathophysiological significance of raised plasma ADMA [PDF]

, 2005
Background Asymmetric dimethylarginine (ADMA) is a naturally occurring inhibitor of nitric oxide synthesis that accumulates in a wide range of diseases associated with endothelial dysfunction and enhanced atherosclerosis.
Achan, Arrigoni, Bachand, Boger, Boger, Cardounel, Caroline L Smith, Casellas, Chambers, Closs, Cooke, Cross, Deng, Dennis, Faruqi, Gorenflo, Hemish, Hosack, Hruska, Ivor Benjamin, James M Leiper, Kearns, Kielstein, MacAllister, Mike Hubank, Millatt, Patrick Vallance, Savvidou, Seo, Shelagh Anthony, Smirnova, Stuhlinger, Suda, Tang, Teerlink, Tsikas, Usui, Valkonen, Vallance, Xiao, Zoccali, Zoccali   +41 more
core   +5 more sources

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Expression, purification and in vitro biological activity from human recombinant BMP-2 produced by a novel approach [PDF]

, 2006
Bone morphogenetic proteins have promoted great biomedical interest due to their ability in inducing new bone formation when used as powerful osteoinductive components of several late-stage bone grafting products.
Bessa, Paulo C., Casal, Margarida, Klosch, B., Nobre, Alexandra, Pedro, A. P., Redl, Heinz, Reis, R. L.   +6 more
core  

Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease. [PDF]

, 2014
The renin-angiotensin system (RAS), bone morphogenetic protein (BMP), and WNT pathways are involved in pathogenesis of diabetic kidney disease (DKD).
Afkarian, Maryam, de Boer, Ian H, Greenbaum, Carla, Himmelfarb, Jonathan, Hirsch, Irl B, Tuttle, Katherine R   +5 more
core   +1 more source

Dexamethasone Enhances Osteogenic Differentiation of Bone Marrow- and Muscle-Derived Stromal Cells and Augments Ectopic Bone Formation Induced by Bone Morphogenetic Protein-2

PLoS ONE, 2015
We evaluated whether dexamethasone augments the osteogenic capability of bone marrow-derived stromal cells (BMSCs) and muscle tissue-derived stromal cells (MuSCs), both of which are thought to contribute to ectopic bone formation induced by bone ...
Masato Yuasa, Tsuyoshi Yamada, Takashi Taniyama, Tomokazu Masaoka, Xuetao Wei, T. Yoshii, M. Horie, Hiroaki Yasuda, T. Uemura, A. Okawa, S. Sotome   +10 more
semanticscholar   +1 more source

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

Accelerators of Osteogenesis by Recombinant Human Bone Morphogenetic Protein-2

Drug Target Insights, 2007
Bone morphogenetic protein (BMP) appears to be one of the most promising cytokine and for clinical use in reconstructive surgery for bony defects and augmentation.
Yasunori Okubo, Kenji Kusumoto, Kazuhisa Bessho   +2 more
doaj   +2 more sources