Results 61 to 70 of about 213,459 (247)

Direct Evidence on the Contribution of a Missense Mutation in GDF9 to Variation in Ovulation Rate of Finnsheep [PDF]

, 2014
peer-reviewedThe Finnish Landrace (Finnsheep) is a well known high-prolificacy sheep breed and has been used in many countries as a source of genetic material to increase fecundity of local breeds.
Hanrahan, James P, Mullen, Michael P.
core   +2 more sources

Bone regeneration with recombinant human bone morphogenetic protein 2: a systematic review [PDF]

Journal of Maxillofacial and Oral Surgery, 2016
The aim of this work was to perform a systematic literature review on the clinical application of rhBMP-2 in bone reconstruction prior to placing implants.A PUBMED search was made about the subject and nine clinical trials were selected according to strict inclusion criteria.Overall success rates of bone regeneration with rhBMP-2 was 81.4% and success ...
Jannice, de Queiroz Fernandes, Valthierre Nunes, de Lima, João Paulo, Bonardi, Osvaldo Magro, Filho, Sormani Bento Fernandes, Queiroz   +4 more
openaire   +2 more sources

Identification of a bone morphogenetic protein type 2 receptor neutralizing antibody

BMC Research Notes, 2019
Objective The bone morphogenetic protein (BMP) signaling pathway comprises the largest subdivision of the transforming growth factor (TGFβ) superfamily.
Ruthann E. Gorrell, Madeline H. Totten, Laura J. Schoerning, Jordan B. Newby, Logan J. Geyman, Warren G. Lawless, Julia M. Hum, Jonathan W. Lowery   +7 more
doaj   +1 more source

Transient Local Bone Remodeling Effects of rhBMP-2 in an Ovine Interbody Spine Fusion Model [PDF]

, 2016
Background: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is a powerful osteoinductive morphogen capable of stimulating the migration of mesenchymal stem cells (MSCs) to the site of implantation and inducing the proliferation and ...
Badura, Jeffrey, Bae, Hyun W., Patel, Vikas V., Pradhan, Ben B., Sardar, Zeeshan M., Seim, Howard, Toth, Jeffrey M., Turner, Anthony S.   +7 more
core   +1 more source

Small molecule-mediated tribbles homolog 3 promotes bone formation induced by bone morphogenetic protein-2. [PDF]

, 2017
Although bone morphogenetic protein-2 (BMP2) has demonstrated extraordinary potential in bone formation, its clinical applications require supraphysiological milligram-level doses that increase postoperative inflammation and inappropriate adipogenesis ...
Aghaloo, Tara L, Cui, Zhong-Kai, Fan, Jiabing, Guo, Mian, Im, Dan CS, Kim, Soyon, Lee, Min, Pi-Anfruns, Joan, Wu, Benjamin M   +8 more
core   +1 more source

Dexamethasone Enhances Osteogenic Differentiation of Bone Marrow- and Muscle-Derived Stromal Cells and Augments Ectopic Bone Formation Induced by Bone Morphogenetic Protein-2

PLoS ONE, 2015
We evaluated whether dexamethasone augments the osteogenic capability of bone marrow-derived stromal cells (BMSCs) and muscle tissue-derived stromal cells (MuSCs), both of which are thought to contribute to ectopic bone formation induced by bone ...
Masato Yuasa, Tsuyoshi Yamada, Takashi Taniyama, Tomokazu Masaoka, Xuetao Wei, T. Yoshii, M. Horie, Hiroaki Yasuda, T. Uemura, A. Okawa, S. Sotome   +10 more
semanticscholar   +1 more source

Short-term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein–2 in a Cancellous Bone Environment [PDF]

, 2009
Study Design. An experimental study investigating osteoclastic activity induced by rhBMP-2 in sheep. Objective. To examine the effects of increasing local rhBMP-2 concentration on osteoclastic response and peri-implant bone resorption.
Badura, Jeffrey, Boden, Scott D., Burkus, J. Kenneth, McKay, William, Peckham, Steve M., Toth, Jeffrey M.   +5 more
core   +1 more source

Pleading Securities Fraud [PDF]

, 2001
Hyaluronan based hydrogel coatings can mimic extracellular matrix components and incorporate growth factors that can be released during a progressive degradation while new tissue regenerates.
Bergman, Berts, Best, Buddula, Chiba, Ciccone, Cubitt, Feiler, Fraser, Golub, Haxaire, Hench, Heymann, Hulsart-Billström, Hunziker, Höök, Kang, Katzer, Liu, Martinez-Sanz, Martínez-Sanz, Morra, Navarro, Nayab, Park, Patterson, Piskounova, Polunina, Sauerbrey, Scheufler, Serro, Vasikaran, Voinova, Voinova, Wozney, Yamanlar, Yang, Yoshinari, Zara, Åberg   +39 more
core   +4 more sources

Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Journal of Applied Oral Science, 2012
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells.
Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon, Cláudia Maria Oliveira Simões   +3 more
doaj  

Regulation of scleral fibroblast differentiation by bone morphogenetic protein-2

International Journal of Ophthalmology, 2014
Bone morphogenesis proteins (BMPs) are multi-functional growth factors. They are expressed in retina, retinal pigment epithelium (RPE) and sclera and serve as a regulator in the growth and development of the eye.
Hong-Hui Li, Li-Jun Huo, Feng Zhao, Zhen-Ya Gao, Jun-Wen Zeng   +4 more
doaj   +1 more source