Results 81 to 90 of about 27,732,661 (195)

Tuning the bioactivity of bone morphogenetic protein-2 with surface immobilization strategies

open access: yes, 2018
Bone morphogenetic protein-2 (BMP-2) involved therapy is of great potential for bone regeneration. However, its clinical application is restricted due to the undesirable bioactivity and relevant complications in vivo. Immobilization of recombinant BMP-2 (
Pan, Yuanzhong   +6 more
core   +1 more source

Humoral Bone Morphogenetic Protein 2 Is Sufficient for Inducing Breast Cancer Microcalcification

open access: yesMolecular Imaging, 2008
Microcalcifications are an important diagnostic marker for breast cancer on mammograms, yet the mechanism of their formation is poorly understood. Indeed, there is presently no short-latency, high-yield, syngeneic rodent model of the process.
Fangbing Liu   +9 more
doaj   +1 more source

The Use of Platelet Rich Plasma, Bone Morphogenetic Protein-2 and Different Scaffolds in Oral and Maxillofacial Surgery - Literature Review in Comparison with Own Clinical Experience

open access: yeseJournal of Oral Maxillofacial Research, 2011
Objectives: The purpose of this article was to review and critically assess the use of platelet rich plasma, recombinant human bone morphogenetic protein-2 and different scaffolds (i.e. tricalciumphosphate, polycaprolactone, demineralized bone matrix and
Karl-Heinz Schuckert   +2 more
doaj  

A new biocompatible delivery scaffold containing heparin and bone morphogenetic protein 2

open access: yesActa Pharmaceutica, 2016
Silicon-substituted calcium phosphate (Si-CaP) was developed in our laboratory as a biomaterial for delivery in bone tissue engineering. It was fabricated as a 3D-construct of scaffolds using chitosan-trisodium polyphosphate (TPP) cross-linked networks ...
Thanyaphoo Suphannee   +1 more
doaj   +1 more source

Blocking c‐Met signaling enhances bone morphogenetic protein‐2‐induced osteoblast differentiation

open access: yesFEBS Open Bio, 2015
We previously demonstrated that blocking hepatocyte growth factor (HGF) receptor/c‐Met signaling inhibited arthritis and articular bone destruction in mouse models of rheumatoid arthritis (RA).
Seiji Shibasaki   +5 more
doaj   +1 more source

Human bone morphogenetic protein (hBMP)

open access: yes, 1983
Human bone morphogenetic protein (hBMP) was chemically extracted from demineralized gelatinized cortical bone matrix by means of a CaCl2 X urea inorganic-organic solvent mixture, differential precipitation in guanidine hydrochloride, and preparative gel ...
Urist, M R   +9 more
core   +1 more source

A Review of the Clinical Side Effects of Bone Morphogenetic Protein-2

open access: yesTissue engineering. Part B, Reviews, 2016
A. James   +7 more
semanticscholar   +1 more source

A correlative immuno-light and electron microscopic study on the type I collagen in the bone morphogenetic protein-induced cartilage [PDF]

open access: yes, 1993
名古屋大学NAGOYA University博士(医学)Bone morphogenetic protein (BMP) partially purified from bovine bone was implanted into the thigh muscles of AKR-strain mice to induce an ectopic endochondral ossification tissue. The extracellular matrix components around the
Mizutani, Hideki   +6 more
core  

Influence of the mechanical environment upon the healing of segmental bone defects in the rat femur [PDF]

open access: yes
Loss of large segments of bone creates critical size defects (CSDs). These fail to heal spontaneously and present major clinical challenges to orthopaedic surgeons. The research described in this thesis is based upon the hypothesis that the healing of
Glatt, Vaida
core  

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