Results 181 to 190 of about 137,665 (299)

The role of the bone morphogenetic protein receptor 2 pathway in group 2 pulmonary hypertension secondary to valvular heart disease. [PDF]

open access: yesERJ Open Res
Martínez-Solano J   +14 more
europepmc   +1 more source

Cellular Signalling Networks in High Altitude Pulmonary Hypertension: From Canonical Pathways to Emerging Targets

open access: yesCell Proliferation, EarlyView.
This review elucidates the intricate cellular signalling networks involved in high‐altitude pulmonary hypertension (HAPH), integrating canonical pathways like HIF, MAPK and BMP with emerging targets such as Wnt/β‐catenin, Notch, Hippo‐YAP and IL‐6. It highlights potential therapeutic strategies targeting these pathways to mitigate vascular remodelling ...
Sheng Ding   +8 more
wiley   +1 more source

Evaluation of tissue response of experimental calcium silicate‐based endodontic sealers: An in vivo study

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract The aim of this study was to evaluate whether the experimental sealers, composed of tricalcium silicate (CaSi) and CaSi supplemented with calcium hypochlorite (CaSi‐H), stimulate tissue repair. The tissue response of experimental materials was compared with commercially available materials Bio‐C sealer (BC sealer) and BioRoot (BROOT ...
Evelin Carine Alves Silva   +5 more
wiley   +1 more source

Construction and validation of risk prediction model for vascular calcification in autogenous arteriovenous fistulas among patients undergoing maintenance hemodialysis

open access: yesHuli yanjiu
ObjectiveTo analyze the influencing factors of vascular calcification in autogenous arteriovenous fistulas among patients undergoing maintenance hemodialysis(MHD) and to construct decision tree model.MethodsA total of 233 patients undergoing MHD treated ...
WANG Chun   +4 more
doaj  

Bone morphogenetic protein-9 controls pulmonary vascular growth and remodeling. [PDF]

open access: yesProc Natl Acad Sci U S A
Berrebeh N   +19 more
europepmc   +1 more source

Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Absence epilepsy is characterized by brief but frequent seizures with loss of consciousness. Existing treatments, which come with heavy side effects, are only partially effective and do not address the associated comorbidities, including cognitive and social deficits.
Coline Rulhe   +9 more
wiley   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

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