Hydrogel‐based therapies have proven to be valuable tools to address the unique regeneration challenges of complex multi‐domain periodontal and craniofacial tissues. This review highlights and classifies clinically approved and emerging hydrogel therapies indicated for the regeneration of periodontal and craniofacial tissues.
Z. Gouveia +5 more
wiley +1 more source
Cost-Effectiveness Analyses of Bone Morphogenetic Protein 2 (rhBMP-2) in Spinal Fusion: A Systematic Review. [PDF]
Nunna RS +10 more
europepmc +1 more source
EMD is one of the few biological agents with human histologic evidence supporting periodontal regeneration. This is reflected in improved clinical outcomes when used in regenerative surgery for intrabony defects. Despite its biological plausibility for broader therapeutic applications, further high‐quality randomized clinical trials are needed to ...
Richard J. Miron +10 more
wiley +1 more source
The Role of Wnt Signaling in Age‐Related Alveolar Bone Loss and Regeneration
The graphical abstract summarizes key signaling pathways involved in bone formation and resorption associated with Wnt signaling across young and aged long bone and jaw tissues. Levels of evidence are indicated as robust, moderate, or emerging, reflecting the current experimental support in each context.
Hsiao H. Sung +12 more
wiley +1 more source
Exploring Bone Morphogenetic Protein-2 and -4 mRNA Expression and Their Receptor Assessment in a Dynamic <i>In Vitro</i> Model of Vascular Calcification. [PDF]
Cabiati M +8 more
europepmc +1 more source
Human macrophage transcriptomic responses to Mycobacterium avium (Mav), a major cause of nontuberculous lung disease, were compared to Mycobacterium tuberculosis (Mtb). Both infections activated overlapping immune pathways, including cytokine signaling and GPCRs involved in lipid metabolism, while phospholipases were more strongly regulated by Mav and ...
Gül Kilinç +4 more
wiley +1 more source
Gold-doped wollastonite nanohybrids enhance bone regeneration <i>via</i> the bone morphogenetic protein-2, SMAD1, and Runt-related transcription factor-2 signalling pathway. [PDF]
Moaness M +6 more
europepmc +1 more source
ABSTRACT Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling.
Ana Raimunda Dâmaso +7 more
wiley +1 more source
Comparative study on lateral maxillary sinus augmentation of without grafting, particle bone grafting and recombinant human bone morphogenetic protein-2+absorbable collagen sponge grafting with simultaneous dental implant placement: a retrospective study. [PDF]
Kang MS +7 more
europepmc +1 more source
Genetic and Molecular Determinants of Familial Transmission of Skeletal Malocclusions
ABSTRACT Families studies conducted in different ethnic populations worldwide have helped elucidate the molecular and genetic factors involved in the development of skeletal class III malocclusion. Therefore, the aim of this study is to provide an updated summary.
Alexandra Dehesa‐Santos +3 more
wiley +1 more source

