Results 1 to 10 of about 27,732,661 (195)

Bone Morphogenetic Protein-2 in Development and Bone Homeostasis

open access: yesJournal of Developmental Biology, 2020
Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the Transforming Growth Factor-Beta (TGF-β) superfamily. These proteins are essential to many developmental processes, including cardiogenesis, neurogenesis, and ...
Daniel Halloran   +2 more
doaj   +2 more sources

Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage [published erratum appears in J Cell Biol 1995 Feb;128(4):following 713]

open access: yesJournal of Cell Biology, 1994
The implantation of bone morphogenetic protein (BMP) into muscular tissues induces ectopic bone formation at the site of implantation. To investigate the mechanism underlying this process, we examined whether recombinant bone morphogenetic protein-2 (BMP-
T. Katagiri   +9 more
exaly   +2 more sources

Bone morphogenetic protein-2-derived osteogenic peptide promotes bone regeneration via osteoblastogenesis [PDF]

open access: yesRegenerative Therapy
Introduction: Bone morphogenetic protein (BMP)-2 plays a critical role in stimulating human mesenchymal stromal cells (hMSCs) differentiation, a key process in bone regeneration.
Jong-Bin Lee   +6 more
doaj   +2 more sources

Focused Ultrasound-Mediated Release of Bone Morphogenetic Protein 2 from Hydrogels for Bone Regeneration [PDF]

open access: yesGels
An ultrasound-responsive hydrogel system was developed that provides on-demand release when stimulated by focused ultrasound (fUS). Diels–Alder cycloadducts crosslinked polyethylene glycol (PEG) hydrogels and underwent a retrograde Diels–Alder reaction ...
Tyus J. Yeingst   +6 more
doaj   +2 more sources

Potentiating effect of AMD3100 on bone morphogenetic protein-2 induced bone regeneration [PDF]

open access: yesMaxillofacial Plastic and Reconstructive Surgery
Background AMD3100, a CXCR4 antagonist, is currently prescribed for activating the mobilization of hematopoietic stem cells. Recently, AMD3100 was shown to potentiate bone morphogenetic protein-2 (BMP-2)-induced bone formation by stimulating the ...
Gyu-Jo Shim   +4 more
doaj   +2 more sources

Assessment of serum levels of bone morphogenetic proteins as sensitive biomarkers for early prediction of acute myocardial infarction. [PDF]

open access: yesEgyptian Journal of Pure and Applied Science, 2023
Although acute myocardial infarction (AMI) is a life-threatening disease, rapid diagnosis may reduce mortality risk. Despite being highly specific for AMI, cardiac troponin I (cTnI) does not distinguish between the etiologically diverse of myocardial ...
Fahmy Ali   +5 more
doaj   +1 more source

Preliminary evaluation of BMP-2-derived peptide in repairing a peri-implant critical size defect: A canine model

open access: yesJournal of the Formosan Medical Association, 2021
Background/Purpose: A synthetic bone morphogenetic protein (BMP)-2-derived peptide has been discovered to promote bone regeneration. The present study investigated the potential of the BMP-2 peptide combined with hydroxyapatite (HAp)/β-tricalcium ...
Yueh-Ling Chao   +3 more
doaj   +1 more source

Engineered bridge protein with dual affinity for bone morphogenetic protein-2 and collagen enhances bone regeneration for spinal fusion

open access: yesScience Advances, 2021
The safety and efficacy of bone morphogenetic protein-2 is improved by the addition of a bridge protein in InFUSE Bone Graft. The revolutionizing efficacy of recombinant human bone morphogenetic protein (rhBMP-2) for clinical spinal fusion is hindered by
P. Briquez   +3 more
semanticscholar   +1 more source

Ectopic Laryngeal Ossification after Bone Morphogenetic Protein-2

open access: yesSurgeries, 2021
We report two cases of ectopic bone formation in the head and neck following treatment with recombinant human bone morphogenetic protein-2 (rhBMP-2). Surgical pathologic data, laryngoscopy imaging, CT imaging, and patient medical history were obtained ...
Kirsten Wong   +2 more
doaj   +1 more source

Bone morphogenetic protein 2: heterologous expression and potential in bone regeneration

open access: yesActualidades Biológicas, 2021
Currently, bone morphogenetic protein 2 (BMP-2) is one of the two osteoinductive growth factors used in medical devices to promote bone formation. Typically, this protein is bought from commercial houses at high rates and in small quantities that are not
Andrea Mesa-Restrepo   +2 more
doaj   +1 more source

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