Results 31 to 40 of about 174,184 (273)

Three-dimensional Printing of Mycelium Hydrogels into Living Complex Materials [PDF]

open access: yes, 2022
Biological living materials, such as animal bones and plant stems, are able to self-heal, regenerate, adapt and make decisions under environmental pressures. Despite recent successful efforts to imbue synthetic materials with some of these remarkable functionalities, many emerging properties of complex adaptive systems found in biology remain ...
arxiv   +1 more source

The Embryonic Chick Femur Organotypic Model as a Tool to Analyze the Angiotensin II Axis on Bone Tissue

open access: yesPharmaceuticals, 2021
Activation of renin–angiotensin system (RAS) plays a role in bone deterioration associated with bone metabolic disorders, via increased Angiotensin II (AngII) targeting Angiotensin II type 1 receptor/Angiotensin II type 2 receptor (AT1R/AT2R).
Thais Francini Garbieri   +4 more
doaj   +1 more source

A parameter study on optimal scaffolds in a simple model for bone regeneration [PDF]

open access: yesarXiv, 2021
We propose a simple model for scaffold aided bone regeneration. In this model, only macroscopic quantities, e.g., locally averaged osteoblast densities, are considered. This allows for use of this model in an optimization algorithm, whose outcome is an optimal scaffold porosity distribution.
arxiv  

Optimal conditions of collagenase treatment for isolation of articular chondrocytes from aged human tissues

open access: yesRegenerative Therapy, 2017
Introduction: There are various types of cartilage, including the auricular and articular cartilages. These cartilages have different functions, and their matrix volume and density of chondrocytes may differ.
Kazumichi Yonenaga   +7 more
doaj   +1 more source

An Efficient Model for Scaffold-Mediated Bone Regeneration [PDF]

open access: yesarXiv, 2021
We present a three dimensional, time dependent model for bone regeneration in the presence of porous scaffolds to bridge critical size bone defects. Our approach uses homogenized quantities, thus drastically reducing computational cost compared to models resolving the microstructural scale of the scaffold.
arxiv  

Three Dimensional Optimization of Scaffold Porosities for Bone Tissue Engineering [PDF]

open access: yesarXiv, 2021
We consider the scaffold design optimization problem associated to the three dimensional, time dependent model for scaffold mediated bone regeneration considered in Dondl et al. (2021). We prove existence of optimal scaffold designs and present numerical evidence that optimized scaffolds mitigate stress shielding effects from exterior fixation of the ...
arxiv  

Comparison of bone formation mediated by bone morphogenetic protein delivered by nanoclay gels with clinical techniques (autograft and InductOs) in an ovine bone model

open access: yesJournal of Tissue Engineering, 2022
Development of a growth factor delivery vehicle providing appropriate temporal-spatial release together with an appropriate preclinical large animal model to evaluate bone formation is critical in the development of delivery strategies for bone tissue ...
Cameron Black   +7 more
doaj   +1 more source

Early Stage Foreign Body Reaction against Biodegradable Polymer Scaffolds Affects Tissue Regeneration during the Autologous Transplantation of Tissue-Engineered Cartilage in the Canine Model

open access: yesCell Transplantation, 2012
To overcome the weak points of the present cartilage regenerative medicine, we applied a porous scaffold for the production of tissue-engineered cartilage with a greater firmness and a 3D structure.
Yukiyo Asawa   +7 more
doaj   +1 more source

Hydrothermal Synthesis of Fluorapatite Coatings over Titanium Implants for Enhanced Osseointegration—An In Vivo Study in the Rabbit

open access: yesJournal of Functional Biomaterials, 2022
This work aims at the development and characterization of fluorapatite coatings, innovatively prepared by the hydrothermal method, aiming for enhanced osseointegration of titanium implants.
Eduardo Santiago   +5 more
doaj   +1 more source

Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization

open access: yesNature Communications, 2020
Nanoclays have been used in composites and for drug delivery but have suffered from a trade-off in properties when used for both. Here the authors report on the use of bisphosphonate interactions with nanoclay edges to made drug loaded composites without
Yang-Hee Kim   +7 more
doaj   +1 more source

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