Results 11 to 20 of about 4,056,235 (345)
Osteoimmunomodulatory Nanoparticles for Bone Regeneration
Nanomaterials, 2023 Treatment of large bone fractures remains a challenge for orthopedists. Bone regeneration is a complex process that includes skeletal cells such as osteoblasts, osteoclasts, and immune cells to regulate bone formation and resorption.
Jingyi Wen +8 more
semanticscholar +8 more sources
Hallmarks of peripheral nerve function in bone regeneration
Bone Research, 2023 Skeletal tissue is highly innervated. Although different types of nerves have been recently identified in the bone, the crosstalk between bone and nerves remains unclear.
R. Tao +8 more
semanticscholar +2 more sources
MicroRNAs and Bone Regeneration [PDF]
Current Genomics, 2015 Bone has multiple functions, both morphologically and physiologically, and it frequently features in the pathological condition, including fracture and osteoporosis. For bone regeneration therapy, the regulation of osteoblast differentiation is important.
Nakasa, Tomoyuki +4 more
openaire +2 more sources
Bioactive Materials, 2022 Regenerating periodontal bone tissues in the aggravated inflammatory periodontal microenvironment under diabetic conditions is a great challenge. Here, a polydopamine-mediated graphene oxide (PGO) and hydroxyapatite nanoparticle (PHA)-incorporated ...
Ya-Zhen Li +10 more
semanticscholar +1 more source
Bone regeneration in inflammation with aging and cell-based immunomodulatory therapy
Inflammation and Regeneration, 2023 Aging of the global population increases the incidence of osteoporosis and associated fragility fractures, significantly impacting patient quality of life and healthcare costs. The acute inflammatory reaction is essential to initiate healing after injury.
J. Kushioka +8 more
semanticscholar +1 more source
FDA-Approved Bone Grafts and Bone Graft Substitute Devices in Bone Regeneration
Materials Science and Engineering C: Materials for Biological Applications, 2021 To induce bone regeneration there is a complex cascade of growth factors. Growth factors such as recombinant BMP-2, BMP-7, and PDGF are FDA-approved therapies in bone regeneration.
C. Gillman, A. Jayasuriya
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 Background: Diabetes-associated periodontitis (DPD) is an inflammatory and destructive disease of periodontal tissues in the diabetic population. The disease is manifested as more severe periodontal destruction and is more difficult to treat when ...
Ruihan Gao +11 more
doaj +1 more source
Drug delivery systems based on polyethylene glycol hydrogels for enhanced bone regeneration
Frontiers in Bioengineering and Biotechnology, 2023 Drug delivery systems composed of osteogenic substances and biological materials are of great significance in enhancing bone regeneration, and appropriate biological carriers are the cornerstone for their construction.
Shou-Ye Sun +9 more
semanticscholar +1 more source
Stem Cell Research & Therapy, 2022 Background The incidence of diabetic osteoporosis is increasing. This article evaluates the effect of combination treatment with the hypoglycemic drug exendin-4 (Ex-4) and the vitamin D analog eldecalcitol (ED-71) on improving diabetic osteoporosis and ...
Yupu Lu +6 more
doaj +1 more source
Bioengineering, 2022 This work intended to elucidate, in an in vitro approach, the cellular and molecular mechanisms occurring during the bone healing process, upon implantation of a tailored degradable multifunctional Mg-based alloy.
Victor Martin +5 more
doaj +1 more source