Results 11 to 20 of about 1,418,143 (292)

Osteoimmunomodulatory Nanoparticles for Bone Regeneration

Nanomaterials, 2023
Treatment of large bone fractures remains a challenge for orthopedists. Bone regeneration is a complex process that includes skeletal cells such as osteoblasts, osteoclasts, and immune cells to regulate bone formation and resorption. Osteoimmunology, studying this complicated process, has recently been used to develop biomaterials for advanced bone ...
Jingyi Wen, Donglin Cai, Wendong Gao, Ruiying He, Yulin Li, Yinghong Zhou, Travis Klein, Lan Xiao, Yin Xiao   +8 more
openaire   +7 more sources

The selection and application of design methodologies for the design of bone tissue scaffolds [PDF]

, 2013
Research motivation: Bone tissue scaffolds offer a way forward in a strategy to change from tissue replacement to tissue regeneration. Bone tissue scaffolds are a combination of a physical construct, with clearly defined three-dimensional spatial ...
Blogg, Ken
core   +7 more sources

Injectable Cell-based Tissue Engineered Bone Formulations [PDF]

, 2010
PhDCurrent golden standard therapy for bone repair and regeneration involves the use of auto grafts. Nevertheless, there are many drawbacks associated with auto grafts including donor site morbidity, requirement for an invasive surgery, post-operative
Ahmadi, Raheleh
core   +4 more sources

Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal

Frontiers in Pharmacology, 2023
Background: Aging and oxidative stress are considered to be the proximal culprits of postmenopausal osteoporosis. Eldecalcitol (ED-71), a new active vitamin D derivative, has shown a good therapeutic effect on different types of osteoporosis, but the ...
Yuying Kou, Yuying Kou, Xing Rong, Xing Rong, Rong Tang, Rong Tang, Yuan Zhang, Yuan Zhang, Panpan Yang, Panpan Yang, Hongrui Liu, Hongrui Liu, Wanli Ma, Wanli Ma, Minqi Li, Minqi Li   +15 more
doaj   +1 more source

Characterizing the hierarchical structures of bioactive sol-gel silicate glass and hybrid scaffolds for bone regeneration [PDF]

, 2012
Bone is the second most widely transplanted tissue after blood. Synthetic alternatives are needed that can reduce the need for transplants and regenerate bone by acting as active temporary templates for bone growth.
Lee, P. D., Jones, Julian R., Jones, J. R., J. V. Hanna, Newport, Robert J., Hanna, J. V., Smith, M. E., Smith, Mark E., Smith, M.E., Martin, R.A., Yue, S., Hanna, John V., R. J. Newport, Martin, R. A., Lee, P.D., Jones, J.R., M. E. Smith, J. R. Jones, Newport, R. J., Martin, Richard A., R. A. Martin, P. D. Lee, Hanna, J.V., S. Yue   +23 more
core   +1 more source

The blood-tendon barrier: identification and characterisation of a novel tissue barrier in tendon blood vessels [PDF]

European Cells & Materials, 2016
Tissue barriers function as “gate keepers” between different compartments (usually blood and tissue) and are formed by specialised membrane-associated proteins, localising to the apicolateral plasma membrane domain of epithelial and endothelial cells. By
C Lehner, R Gehwolf, JC Ek, S Korntner, H Bauer, H-C Bauer, A Traweger, H Tempfer   +7 more
doaj   +1 more source

Tenophages: a novel macrophage-like tendon cell population expressing CX3CL1 and CX3CR1

Disease Models & Mechanisms, 2019
Tendon disorders frequently occur and recent evidence has clearly implicated the presence of immune cells and inflammatory events during early tendinopathy. However, the origin and properties of these cells remain poorly defined.
Christine Lehner, Gabriel Spitzer, Renate Gehwolf, Andrea Wagner, Nadja Weissenbacher, Christian Deininger, Katja Emmanuel, Florian Wichlas, Herbert Tempfer, Andreas Traweger   +9 more
doaj   +1 more source

Allergy-induced systemic inflammation impairs tendon quality

EBioMedicine, 2022
Summary: Background: Treatment of degenerating tendons still presents a major challenge, since the aetiology of tendinopathies remains poorly understood.
Christine Lehner, Gabriel Spitzer, Patrick Langthaler, Dominika Jakubecova, Barbara Klein, Nadja Weissenbacher, Andrea Wagner, Renate Gehwolf, Eugen Trinka, Bernhard Iglseder, Bernhard Paulweber, Ludwig Aigner, Sebastien Couillard-Després, Richard Weiss, Herbert Tempfer, Andreas Traweger   +15 more
doaj   +1 more source

Global Responses of Il-1β-Primed 3D Tendon Constructs to Treatment with Pulsed Electromagnetic Fields

Cells, 2019
Tendinopathy is accompanied by a cascade of inflammatory events promoting tendon degeneration. Among various cytokines, interleukin-1β plays a central role in driving catabolic processes, ultimately resulting in the activation of matrix ...
Renate Gehwolf, Bettina Schwemberger, Malik Jessen, Stefanie Korntner, Andrea Wagner, Christine Lehner, Nadja Weissenbacher, Herbert Tempfer, Andreas Traweger   +8 more
doaj   +1 more source

Guided bone regeneration

Journal of the Korean Association of Oral and Maxillofacial Surgeons, 2020
Guided bone regeneration (GBR) is a surgical procedure that utilizes bone grafts with barrier membranes to reconstruct small defects around dental implants. This procedure is commonly deployed on dehiscence or fenestration defects ≥2 mm, and mixing with autogenous bone is recommended on larger defects.
Young-Kyun Kim, Jeong-Kui Ku
openaire   +3 more sources