Results 31 to 40 of about 216,236 (317)

Bone Tissue Engineering and Regeneration [PDF]

BioMed Research International, 2014
Bone tissue engineering and regeneration constitutes a burgeoning new area of investigation, incorporating scientists, engineers, and clinicians with diverse academic backgrounds. With an aging global population, the need to engineer and regenerate mesenchymal tissues becomes even more pressing.
Levi, Benjamin, Péault, Bruno, James, Aaron W   +2 more
openaire   +2 more sources

The Embryonic Chick Femur Organotypic Model as a Tool to Analyze the Angiotensin II Axis on Bone Tissue

Pharmaceuticals, 2021
Activation of renin–angiotensin system (RAS) plays a role in bone deterioration associated with bone metabolic disorders, via increased Angiotensin II (AngII) targeting Angiotensin II type 1 receptor/Angiotensin II type 2 receptor (AT1R/AT2R).
Thais Francini Garbieri, Victor Martin, Carlos Ferreira Santos, Pedro de Sousa Gomes, Maria Helena Fernandes   +4 more
doaj   +1 more source

In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint

Biomedicines, 2021
Biodegradable and bioresponsive polymer-based nanoparticles (NPs) can be used for oligonucleotide delivery, making them a promising candidate for mRNA-based therapeutics.
Lisa Sturm, Bettina Schwemberger, Ursula Menzel, Sonja Häckel, Christoph E. Albers, Christian Plank, Jaap Rip, Mauro Alini, Andreas Traweger, Sibylle Grad, Valentina Basoli   +10 more
doaj   +1 more source

Perfluorodecalin and bone regeneration

European Cells and Materials, 2013
Perfluorodecalin (PFD) is a chemically and biologically inert biomaterial and, as many perfluorocarbons, is also hydrophobic, radiopaque and has a high solute capacity for gases such as oxygen. In this article we have demonstrated, both in vitro and in vivo, that PFD may significantly enhance bone regeneration. Firstly, the potential benefit of PFD was
F Tamimi, P Comeau, D Le Nihouannen, YL Zhang, DC Bassett, S Khalili, U Gbureck, SD Tran, S Komarova, JE Barralet   +9 more
openaire   +3 more sources

Optimal conditions of collagenase treatment for isolation of articular chondrocytes from aged human tissues

Regenerative Therapy, 2017
Introduction: There are various types of cartilage, including the auricular and articular cartilages. These cartilages have different functions, and their matrix volume and density of chondrocytes may differ.
Kazumichi Yonenaga, Satoru Nishizawa, Takumi Nakagawa, Yuko Fujihara, Yukiyo Asawa, Atsuhiko Hikita, Tsuyoshi Takato, Kazuto Hoshi   +7 more
doaj   +1 more source

Comparison of bone formation mediated by bone morphogenetic protein delivered by nanoclay gels with clinical techniques (autograft and InductOs) in an ovine bone model

Journal of Tissue Engineering, 2022
Development of a growth factor delivery vehicle providing appropriate temporal-spatial release together with an appropriate preclinical large animal model to evaluate bone formation is critical in the development of delivery strategies for bone tissue ...
Cameron Black, David Gibbs, Josephine McEwan, Janos Kanczler, Marta Peña Fernández, Gianluca Tozzi, Jonathan Dawson, Richard Oreffo   +7 more
doaj   +1 more source

Biomaterials for bone regeneration

Medicina Oral Patología Oral y Cirugia Bucal, 2010
This article reviews the literature on biomaterials used for bone regeneration.A total of seventeen bibliographic sources were found using the MEDLINE database and to avoid the variability of the search terms the thesaurus Mesh was used.These materials act essentially due to their osteoconductive ability, although their osteoinductive capacity is being
Pérez Sánchez, María José, Ramírez Glindon, Elena, Lledó Gil, Miguel, Calvo Guirado, José Luis, Pérez Sánchez, Cristina   +4 more
openaire   +3 more sources

Early Stage Foreign Body Reaction against Biodegradable Polymer Scaffolds Affects Tissue Regeneration during the Autologous Transplantation of Tissue-Engineered Cartilage in the Canine Model

Cell Transplantation, 2012
To overcome the weak points of the present cartilage regenerative medicine, we applied a porous scaffold for the production of tissue-engineered cartilage with a greater firmness and a 3D structure.
Yukiyo Asawa, Tomoaki Sakamoto, Makoto Komura, Makoto Watanabe, Satoru Nishizawa, Yutaka Takazawa, Tsuyoshi Takato, Kazuto Hoshi M.D., Ph.D.   +7 more
doaj   +1 more source

Hydrothermal Synthesis of Fluorapatite Coatings over Titanium Implants for Enhanced Osseointegration—An In Vivo Study in the Rabbit

Journal of Functional Biomaterials, 2022
This work aims at the development and characterization of fluorapatite coatings, innovatively prepared by the hydrothermal method, aiming for enhanced osseointegration of titanium implants.
Eduardo Santiago, Victor Martin, Bruno Colaço, Maria Helena Fernandes, Catarina Santos, Pedro S. Gomes   +5 more
doaj   +1 more source

Synergistic effect of umbilical cord extracellular vesicles and rhBMP-2 to enhance the regeneration of a metaphyseal femoral defect in osteoporotic rats

Stem Cell Research & Therapy
Background The aim of this study was to evaluate potential synergistic effects of a single, local application of human umbilical cord MSC-derived sEVs in combination with a low dose of recombinant human rhBMP-2 to promote the regeneration of a ...
Amelie Deluca, Andrea Wagner, Patrick Heimel, Christian Deininger, Florian Wichlas, Heinz Redl, Eva Rohde, Herbert Tempfer, Mario Gimona, Andreas Traweger   +9 more
doaj   +1 more source