Results 31 to 40 of about 1,418,143 (292)

Unveiling the Osteogenic Potential of Tetracyclines: A Comparative Study in Human Mesenchymal Stem Cells

open access: yesCells, 2023
Tetracyclines (TCs) are a class of broad-spectrum antibiotics with diverse pharmacotherapeutic properties due to their various functional groups being attached to a common core structure.
Victor Martin   +4 more
doaj   +1 more source

Endothelialized tissue engineered 3D-construct for bone repair [PDF]

open access: yes, 2005
One of the main problems arising when implanting a graft into a large bone gap is its insufficient vascularization in the central region. This results in impaired bone healing and often leads to necrosis in the graft.
Meury, Thomas
core   +1 more source

Porous Nanomaterials Targeting Autophagy in Bone Regeneration

open access: yes, 2021
Porous nanomaterials (PNMs) are nanosized materials with specially designed porous structures that have been widely used in the bone tissue engineering field due to the fact of their excellent physical and chemical properties such as high porosity, high ...
Lan Xiao   +5 more
core   +1 more source

Peroxiredoxin 1 regulates crosstalk between pyroptosis and autophagy in oral squamous cell carcinoma leading to a potential pro-survival

open access: yesCell Death Discovery, 2023
Peroxiredoxin 1 (Prdx1), a vital antioxidant enzyme, has been proven to play an important role in the occurrence and development of cancers, but its effects on oral squamous cell carcinoma (OSCC) remain unclear. Here, we performed bioinformatics analysis
Meilin Ye   +7 more
doaj   +1 more source

The Synergistic Effect of Zuogui Pill and Eldecalcitol on Improving Bone Mass and Osteogenesis in Type 2 Diabetic Osteoporosis

open access: yesMedicina, 2023
Background and Objectives: The incidence of diabetic osteoporosis, an important complication of diabetes mellitus, is increasing gradually. This study investigated the combined effect of the Zuogui pill (ZGP) and eldecalcitol (ED-71), a novel vitamin D ...
Tuo Shi   +8 more
doaj   +1 more source

Optimal conditions of collagenase treatment for isolation of articular chondrocytes from aged human tissues

open access: yesRegenerative Therapy, 2017
Introduction: There are various types of cartilage, including the auricular and articular cartilages. These cartilages have different functions, and their matrix volume and density of chondrocytes may differ.
Kazumichi Yonenaga   +7 more
doaj   +1 more source

The Embryonic Chick Femur Organotypic Model as a Tool to Analyze the Angiotensin II Axis on Bone Tissue

open access: yesPharmaceuticals, 2021
Activation of renin–angiotensin system (RAS) plays a role in bone deterioration associated with bone metabolic disorders, via increased Angiotensin II (AngII) targeting Angiotensin II type 1 receptor/Angiotensin II type 2 receptor (AT1R/AT2R).
Thais Francini Garbieri   +4 more
doaj   +1 more source

Bone regeneration and stem cells [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2011
This invited review covers research areas of central importance for orthopaedic and maxillofacial bone tissue repair, including normal fracture healing and healing problems, biomaterial scaffolds for tissue engineering, mesenchymal and foetal stem cells, effects of sex steroids on mesenchymal stem cells, use of platelet-rich plasma for tissue repair ...
Arvidson K.   +12 more
openaire   +6 more sources

In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint

open access: yesBiomedicines, 2021
Biodegradable and bioresponsive polymer-based nanoparticles (NPs) can be used for oligonucleotide delivery, making them a promising candidate for mRNA-based therapeutics.
Lisa Sturm   +10 more
doaj   +1 more source

Injectable Scaffolds for Bone Regeneration [PDF]

open access: yesLangmuir, 2014
Clinical treatments of significant bone defects involve invasive procedures such as the application of auto- and allografts. These procedures present many limitations including the potential for infection and rejection. There is therefore a need to develop novel therapeutic strategies able to exploit the natural regenerative potential of bone and that ...
Yasmeen, Sabina   +3 more
openaire   +4 more sources

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