Results 41 to 50 of about 1,418,143 (292)

Limitations of bone formation in oral implantology: inhibition of osteoblast functions by gingival tissues [PDF]

, 2010
PhDClinical observation suggest that bone formation is influenced by the environmental niche where it takes place and specifically that soft connective tissues may inhibit the bone healing process.
Al-Masri, Maher
core   +4 more sources

Perfluorodecalin and bone regeneration

European Cells and Materials, 2013
Perfluorodecalin (PFD) is a chemically and biologically inert biomaterial and, as many perfluorocarbons, is also hydrophobic, radiopaque and has a high solute capacity for gases such as oxygen. In this article we have demonstrated, both in vitro and in vivo, that PFD may significantly enhance bone regeneration. Firstly, the potential benefit of PFD was
F Tamimi, P Comeau, D Le Nihouannen, YL Zhang, DC Bassett, S Khalili, U Gbureck, SD Tran, S Komarova, JE Barralet   +9 more
openaire   +3 more sources

Composite Hydrogels for Bone Regeneration [PDF]

Materials, 2016
Over the past few decades, bone related disorders have constantly increased. Among all pathological conditions, osteoporosis is one of the most common and often leads to bone fractures. This is a massive burden and it affects an estimated 3 million people only in the UK. Furthermore, as the population ages, numbers are due to increase. In this context,
Gianluca Tozzi, Arianna De Mori, Antero Oliveira, Marta Roldo   +3 more
openaire   +4 more sources

Early Stage Foreign Body Reaction against Biodegradable Polymer Scaffolds Affects Tissue Regeneration during the Autologous Transplantation of Tissue-Engineered Cartilage in the Canine Model

Cell Transplantation, 2012
To overcome the weak points of the present cartilage regenerative medicine, we applied a porous scaffold for the production of tissue-engineered cartilage with a greater firmness and a 3D structure.
Yukiyo Asawa, Tomoaki Sakamoto, Makoto Komura, Makoto Watanabe, Satoru Nishizawa, Yutaka Takazawa, Tsuyoshi Takato, Kazuto Hoshi M.D., Ph.D.   +7 more
doaj   +1 more source

Bone Tissue Engineering and Regeneration [PDF]

BioMed Research International, 2014
Bone tissue engineering and regeneration constitutes a burgeoning new area of investigation, incorporating scientists, engineers, and clinicians with diverse academic backgrounds. With an aging global population, the need to engineer and regenerate mesenchymal tissues becomes even more pressing.
Levi, Benjamin, Péault, Bruno, James, Aaron W   +2 more
openaire   +2 more sources

Synergistic effect of umbilical cord extracellular vesicles and rhBMP-2 to enhance the regeneration of a metaphyseal femoral defect in osteoporotic rats

Stem Cell Research & Therapy
Background The aim of this study was to evaluate potential synergistic effects of a single, local application of human umbilical cord MSC-derived sEVs in combination with a low dose of recombinant human rhBMP-2 to promote the regeneration of a ...
Amelie Deluca, Andrea Wagner, Patrick Heimel, Christian Deininger, Florian Wichlas, Heinz Redl, Eva Rohde, Herbert Tempfer, Mario Gimona, Andreas Traweger   +9 more
doaj   +1 more source

Comparison of bone formation mediated by bone morphogenetic protein delivered by nanoclay gels with clinical techniques (autograft and InductOs) in an ovine bone model

Journal of Tissue Engineering, 2022
Development of a growth factor delivery vehicle providing appropriate temporal-spatial release together with an appropriate preclinical large animal model to evaluate bone formation is critical in the development of delivery strategies for bone tissue ...
Cameron Black, David Gibbs, Josephine McEwan, Janos Kanczler, Marta Peña Fernández, Gianluca Tozzi, Jonathan Dawson, Richard Oreffo   +7 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity

Advanced Science
Tendinopathy is a long‐lasting, debilitating disease that not only affects patients' individual lives, but also imposes a significant socioeconomic burden.
Renate Gehwolf, Herbert Tempfer, Nevra Pelin Cesur, Andrea Wagner, Andreas Traweger, Christine Lehner   +5 more
doaj   +1 more source

Hydrothermal Synthesis of Fluorapatite Coatings over Titanium Implants for Enhanced Osseointegration—An In Vivo Study in the Rabbit

Journal of Functional Biomaterials, 2022
This work aims at the development and characterization of fluorapatite coatings, innovatively prepared by the hydrothermal method, aiming for enhanced osseointegration of titanium implants.
Eduardo Santiago, Victor Martin, Bruno Colaço, Maria Helena Fernandes, Catarina Santos, Pedro S. Gomes   +5 more
doaj   +1 more source