Results 21 to 30 of about 386,409 (314)

MicroRNAs and Bone Regeneration [PDF]

Current Genomics, 2015
Bone has multiple functions, both morphologically and physiologically, and it frequently features in the pathological condition, including fracture and osteoporosis. For bone regeneration therapy, the regulation of osteoblast differentiation is important.
Nakasa, Tomoyuki, Yoshizuka, Masaaki, Andry Usman, Muhammad, Elbadry Mahmoud, Elhussein, Ochi, Mitsuo   +4 more
openaire   +2 more sources

Custom 3D-Printed Triflange Implants for Treatment of Severe Acetabular Defects, with and without Pelvic Discontinuity

JBJS Open Access, 2021
Background:. Treatment of massive acetabular defects, both with and without pelvic discontinuity, is challenging. The implants utilized in the surgical procedure need to be stable and integrate with poor host bone stock. In the present study, we describe
Vitali Goriainov, BM, FRCS(Orth), Msc, PhD, Leonard J. King, MB, ChB, FRCP, FRCR, Richard O.C. Oreffo, DPhil, DSc(Oxon), FHEA, CBiol, FRSB, FIOR, Douglas G. Dunlop, MBBCh, FRCS, FRCSEd(TR&Orth), MD   +3 more
doaj   +1 more source

Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway

Molecules, 2019
Diallyl disulfide (DADs), a natural organic compound, is extracted from garlic and scallion and has anti-tumor effects against various tumors. This study investigated the anti-tumor activity of DADs in human osteosarcoma cells and the mechanisms.
Ziqi Yue, Xin Guan, Rui Chao, Cancan Huang, Dongfang Li, Panpan Yang, Shanshan Liu, Tomoka Hasegawa, Jie Guo, Minqi Li   +9 more
doaj   +1 more source

Unveiling the Osteogenic Potential of Tetracyclines: A Comparative Study in Human Mesenchymal Stem Cells

Cells, 2023
Tetracyclines (TCs) are a class of broad-spectrum antibiotics with diverse pharmacotherapeutic properties due to their various functional groups being attached to a common core structure.
Victor Martin, Ana Francisca Bettencourt, Catarina Santos, Maria Helena Fernandes, Pedro Sousa Gomes   +4 more
doaj   +1 more source

3D Printed TCP-Based Scaffold Incorporating VEGF-Loaded PLGA Microspheres for Craniofacial Tissue Engineering [PDF]

, 2017
Objective Vascularization is a critical process during bone regeneration/repair and the lack of tissue vascularization is recognized as a major challenge in applying bone tissue engineeringmethods for cranial and maxillofacial surgeries.
D. Lobner, E. Dashtimoghadam, F. Bastami, F. Fahimipour, K. Khoshroo, L. Tayebi, M. Rasoulianboroujeni, M. Tahriri   +7 more
core   +2 more sources

PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. [PDF]

, 2019
Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for
Shams, Shahin, Silva, Eduardo A, Stilhano, Roberta S, Yamaguchi, Fabio SM   +3 more
core   +1 more source

Peroxiredoxin 1 regulates crosstalk between pyroptosis and autophagy in oral squamous cell carcinoma leading to a potential pro-survival

Cell Death Discovery, 2023
Peroxiredoxin 1 (Prdx1), a vital antioxidant enzyme, has been proven to play an important role in the occurrence and development of cancers, but its effects on oral squamous cell carcinoma (OSCC) remain unclear. Here, we performed bioinformatics analysis
Meilin Ye, Ting Liu, Shanshan Liu, Rong Tang, Hongrui Liu, Fan Zhang, Shenglei Luo, Minqi Li   +7 more
doaj   +1 more source

The Synergistic Effect of Zuogui Pill and Eldecalcitol on Improving Bone Mass and Osteogenesis in Type 2 Diabetic Osteoporosis

Medicina, 2023
Background and Objectives: The incidence of diabetic osteoporosis, an important complication of diabetes mellitus, is increasing gradually. This study investigated the combined effect of the Zuogui pill (ZGP) and eldecalcitol (ED-71), a novel vitamin D ...
Tuo Shi, Ting Liu, Yuying Kou, Xing Rong, Lingxiao Meng, Yajun Cui, Ruihan Gao, Sumin Hu, Minqi Li   +8 more
doaj   +1 more source

Porcine bone scaffolds adsorb growth factors secreted by MSCs and improve bone tissue repair [PDF]

, 2017
An ideal tissue-engineered bone graft should have both excellent pro-osteogenesis and pro-angiogenesis properties to rapidly realize the bone regeneration in vivo . To meet this goal, in this work a porcine bone scaffold was successfully used as a Trojan
Bressan, Eriberto, Ferroni, Letizia, Gardin, Chiara, Mijiritsky, Eitan, Piattelli, Adriano, Zanette, Gastone, Zavan, Barbara   +6 more
core   +2 more sources

Nanomaterials and bone regeneration [PDF]

Bone Research, 2015
The worldwide incidence of bone disorders and conditions has been increasing. Bone is a nanomaterials composed of organic (mainly collagen) and inorganic (mainly nano-hydroxyapatite) components, with a hierarchical structure ranging from nanoscale to macroscale.
Gong, Tao, Xie, Jing, Liao, Jinfeng, Zhang, Tao, Lin, Shiyu, Lin, Yunfeng   +5 more
openaire   +2 more sources