Results 21 to 30 of about 216,236 (317)

Nanomaterials and bone regeneration [PDF]

open access: yesBone Research, 2015
The worldwide incidence of bone disorders and conditions has been increasing. Bone is a nanomaterials composed of organic (mainly collagen) and inorganic (mainly nano-hydroxyapatite) components, with a hierarchical structure ranging from nanoscale to macroscale.
Gong, Tao   +5 more
openaire   +2 more sources

Custom 3D-Printed Triflange Implants for Treatment of Severe Acetabular Defects, with and without Pelvic Discontinuity

open access: yesJBJS Open Access, 2021
Background:. Treatment of massive acetabular defects, both with and without pelvic discontinuity, is challenging. The implants utilized in the surgical procedure need to be stable and integrate with poor host bone stock. In the present study, we describe
Vitali Goriainov, BM, FRCS(Orth), Msc, PhD   +3 more
doaj   +1 more source

Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway

open access: yesMolecules, 2019
Diallyl disulfide (DADs), a natural organic compound, is extracted from garlic and scallion and has anti-tumor effects against various tumors. This study investigated the anti-tumor activity of DADs in human osteosarcoma cells and the mechanisms.
Ziqi Yue   +9 more
doaj   +1 more source

Unveiling the Osteogenic Potential of Tetracyclines: A Comparative Study in Human Mesenchymal Stem Cells

open access: yesCells, 2023
Tetracyclines (TCs) are a class of broad-spectrum antibiotics with diverse pharmacotherapeutic properties due to their various functional groups being attached to a common core structure.
Victor Martin   +4 more
doaj   +1 more source

Bone regeneration and stem cells [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2011
This invited review covers research areas of central importance for orthopaedic and maxillofacial bone tissue repair, including normal fracture healing and healing problems, biomaterial scaffolds for tissue engineering, mesenchymal and foetal stem cells, effects of sex steroids on mesenchymal stem cells, use of platelet-rich plasma for tissue repair ...
Arvidson K.   +12 more
openaire   +6 more sources

Osteoimmunomodulatory Nanoparticles for Bone Regeneration

open access: yesNanomaterials, 2023
Treatment of large bone fractures remains a challenge for orthopedists. Bone regeneration is a complex process that includes skeletal cells such as osteoblasts, osteoclasts, and immune cells to regulate bone formation and resorption. Osteoimmunology, studying this complicated process, has recently been used to develop biomaterials for advanced bone ...
Jingyi Wen   +8 more
openaire   +6 more sources

Injectable Scaffolds for Bone Regeneration [PDF]

open access: yesLangmuir, 2014
Clinical treatments of significant bone defects involve invasive procedures such as the application of auto- and allografts. These procedures present many limitations including the potential for infection and rejection. There is therefore a need to develop novel therapeutic strategies able to exploit the natural regenerative potential of bone and that ...
Yasmeen, Sabina   +3 more
openaire   +4 more sources

Peroxiredoxin 1 regulates crosstalk between pyroptosis and autophagy in oral squamous cell carcinoma leading to a potential pro-survival

open access: yesCell Death Discovery, 2023
Peroxiredoxin 1 (Prdx1), a vital antioxidant enzyme, has been proven to play an important role in the occurrence and development of cancers, but its effects on oral squamous cell carcinoma (OSCC) remain unclear. Here, we performed bioinformatics analysis
Meilin Ye   +7 more
doaj   +1 more source

The Synergistic Effect of Zuogui Pill and Eldecalcitol on Improving Bone Mass and Osteogenesis in Type 2 Diabetic Osteoporosis

open access: yesMedicina, 2023
Background and Objectives: The incidence of diabetic osteoporosis, an important complication of diabetes mellitus, is increasing gradually. This study investigated the combined effect of the Zuogui pill (ZGP) and eldecalcitol (ED-71), a novel vitamin D ...
Tuo Shi   +8 more
doaj   +1 more source

Composite Hydrogels for Bone Regeneration [PDF]

open access: yesMaterials, 2016
Over the past few decades, bone related disorders have constantly increased. Among all pathological conditions, osteoporosis is one of the most common and often leads to bone fractures. This is a massive burden and it affects an estimated 3 million people only in the UK. Furthermore, as the population ages, numbers are due to increase. In this context,
Gianluca Tozzi   +3 more
openaire   +4 more sources

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