Results 41 to 50 of about 2,650,892 (412)

MicroRNAs and Bone Regeneration [PDF]

Current Genomics, 2015
Bone has multiple functions, both morphologically and physiologically, and it frequently features in the pathological condition, including fracture and osteoporosis. For bone regeneration therapy, the regulation of osteoblast differentiation is important.
Nakasa, Tomoyuki, Yoshizuka, Masaaki, Andry Usman, Muhammad, Elbadry Mahmoud, Elhussein, Ochi, Mitsuo   +4 more
openaire   +2 more sources

Custom 3D-Printed Triflange Implants for Treatment of Severe Acetabular Defects, with and without Pelvic Discontinuity

JBJS Open Access, 2021
Background:. Treatment of massive acetabular defects, both with and without pelvic discontinuity, is challenging. The implants utilized in the surgical procedure need to be stable and integrate with poor host bone stock. In the present study, we describe
Vitali Goriainov, BM, FRCS(Orth), Msc, PhD, Leonard J. King, MB, ChB, FRCP, FRCR, Richard O.C. Oreffo, DPhil, DSc(Oxon), FHEA, CBiol, FRSB, FIOR, Douglas G. Dunlop, MBBCh, FRCS, FRCSEd(TR&Orth), MD   +3 more
doaj   +1 more source

Msx1+ stem cells recruited by bioactive tissue engineering graft for bone regeneration

Nature Communications, 2022
Critical-sized bone defects often lead to non-union and full-thickness defects of the calvarium specifically still present reconstructive challenges. In this study, we show that neurotrophic supplements induce robust in vitro expansion of mesenchymal ...
Xianzhu Zhang, Wei Jiang, Chang Xie, Xinyu Wu, Qian Ren, Fei Wang, X. Shen, Yi Hong, Hongwei Wu, Youguo Liao, Yi Zhang, Renjie Liang, Wei Sun, Yuqing Gu, Tao Zhang, Yishan Chen, Wei Wei, Shufang Zhang, Weiguo Zou, H. Ouyang   +19 more
semanticscholar   +1 more source

Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway

Molecules, 2019
Diallyl disulfide (DADs), a natural organic compound, is extracted from garlic and scallion and has anti-tumor effects against various tumors. This study investigated the anti-tumor activity of DADs in human osteosarcoma cells and the mechanisms.
Ziqi Yue, Xin Guan, Rui Chao, Cancan Huang, Dongfang Li, Panpan Yang, Shanshan Liu, Tomoka Hasegawa, Jie Guo, Minqi Li   +9 more
doaj   +1 more source

PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. [PDF]

, 2019
Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for
Shams, Shahin, Silva, Eduardo A, Stilhano, Roberta S, Yamaguchi, Fabio SM   +3 more
core   +1 more source

Strontium-incorporated bioceramic scaffolds for enhanced osteoporosis bone regeneration

Bone Research, 2022
The restoration of bone defects caused by osteoporosis remains a challenge for surgeons. Strontium ranelate has been applied in preventative treatment approaches due to the biological functions of the trace element strontium (Sr). In this study, we aimed
Qianju Wu, Longwei Hu, Ran Yan, Junfeng Shi, Hao Gu, Yuwei Deng, Ruixue Jiang, J. Wen, Xinquan Jiang   +8 more
semanticscholar   +1 more source

Peroxiredoxin 1 regulates crosstalk between pyroptosis and autophagy in oral squamous cell carcinoma leading to a potential pro-survival

Cell Death Discovery, 2023
Peroxiredoxin 1 (Prdx1), a vital antioxidant enzyme, has been proven to play an important role in the occurrence and development of cancers, but its effects on oral squamous cell carcinoma (OSCC) remain unclear. Here, we performed bioinformatics analysis
Meilin Ye, Ting Liu, Shanshan Liu, Rong Tang, Hongrui Liu, Fan Zhang, Shenglei Luo, Minqi Li   +7 more
doaj   +1 more source

The Synergistic Effect of Zuogui Pill and Eldecalcitol on Improving Bone Mass and Osteogenesis in Type 2 Diabetic Osteoporosis

Medicina, 2023
Background and Objectives: The incidence of diabetic osteoporosis, an important complication of diabetes mellitus, is increasing gradually. This study investigated the combined effect of the Zuogui pill (ZGP) and eldecalcitol (ED-71), a novel vitamin D ...
Tuo Shi, Ting Liu, Yuying Kou, Xing Rong, Lingxiao Meng, Yajun Cui, Ruihan Gao, Sumin Hu, Minqi Li   +8 more
doaj   +1 more source

Innovative Concepts and Recent Breakthrough for Engineered Graft and Constructs for Bone Regeneration: A Literature Systematic Review

Materials, 2022
Background: For decades, regenerative medicine and dentistry have been improved with new therapies and innovative clinical protocols. The aim of the present investigation was to evaluate through a critical review the recent innovations in the field of ...
F. Inchingolo, D. Hazballa, A. Inchingolo, G. Malcangi, G. Marinelli, A. Mancini, M. Maggiore, I. R. Bordea, A. Scarano, Marco Farronato, G. Tartaglia, F. Lorusso, A. Inchingolo, G. Dipalma   +13 more
semanticscholar   +1 more source

Development of an injectable composite for bone regeneration [PDF]

, 2013
With the development of minimally invasive surgical techniques, there is a growing interest in the research and development of injectable biomaterials especially for orthopedic applications.
Amédée, Joelle, Anagnostou, Fani, Auzély-Velty, Rachel, Bareille, Reine, Belime, Agathe, Bignon, Aurélien, Brouillet, Fabien, Combes, Christèle, Cordier, Delphine, El Kissi, Nadia, Fatnassi, Mohamed, Galliard, Hélène, Girod-Fullana, Sophie, Hénocq-Pigasse, Christel, Jacquart, Sylvaine, Rey, Christian, Roques, Christine, Siadous, Robin, Tadier, Solène   +18 more
core   +6 more sources