Results 131 to 140 of about 217,854 (311)

Close to the bone: investigations into bone tissue mineralisation and mechanobiology of osteoporosis

, 2012
Osteoporosis is a metabolic skeletal disease characterized by low bone mass, depleted micro-architecture and reduced strength. The public health costs of osteoporosis relate almost entirely to the fractures that are the clinical manifestation of the ...
Brennan, Meadhbh
core  

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Fibroblast–immune crosstalk in oral squamous cell carcinoma: from tumor promotion to immune evasion

Frontiers in Immunology
Oral squamous cell carcinoma (OSCC) is a highly invasive malignancy marked by poor prognosis and therapeutic resistance. Within its tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) and immune cells form a dynamic network that drives ...
Xiao Liu, Xiao Liu, Dandan Wang, Dandan Wang, Xue Cheng, Xue Cheng, Yining Ma, Yining Ma, Siya Li, Jinhai Deng, Chunyan Qiao, Chunyan Qiao   +11 more
doaj   +1 more source

The bone remodeling environment is a factor in breast cancer bone metastasis

, 2011
The bone microenvironment is clearly an important determinant of breast cancer metastasis to bone. Once established in bone, the ability for breast cancer cells to hijack normal regulatory pathways for osteoclast differentiation, activation, and survival
Bilinski, Kellie (R18510), Zheng, Yu, Ooi, Li Liane, Dunstan, Colin R.   +3 more
core   +1 more source

Double‐Transition‐Metal MXenes: Multimetallic 2D Platforms for Next‐Generation Biomedicine

Advanced Materials, EarlyView.
The present work explores recent progress in double‐transition‐metal MXenes and focuses on their potential as multifunctional biomedical nanoplatforms whose tunable optical, electronic, mechanical, and surface properties enable imaging, theranostics, antimicrobial activity, biosensing, tissue engineering, and drug delivery.
Parsa Namakiaraghi, Mohammad Mozafari, Masoud Soroush   +2 more
wiley   +1 more source

Computational simulation of the mechanobiological regulation of bone remodeling by means of a coupled systems biology-micromechanical approach

, 2012
Bone remodeling involves the coordinated removal of bone by osteoclasts and addition of bone by osteoblasts, a process that is modulated by the prevailing mechanical environment.
Pivonka, P., Scheiner, S., Smith, D. W., Stefan Scheiner, David W. Smith, Hellmich, C., Peter Pivonka, Christian Hellmich   +7 more
core   +1 more source

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

Cell membrane biomimetic nanoplatforms: a new strategy for immune escape and precision targeted therapy

Materials Today Bio
Cell membrane biomimetic nanoplatforms represent an innovative approach to addressing key challenges in nanodrug delivery systems by encapsulating natural cell membranes onto nanomaterials. This strategy confers unique biological properties that overcome
Jian Feng, Dixin He, Jingxia Chen, Mucong Li, Jiaxin Luo, Yuzhu Han, Xuyan Wei, Sicong Ren, Zhibo Wang, Yunxiao Wu, Hanchi Wang, Yidi Zhang, Yanmin Zhou   +12 more
doaj   +1 more source

BONE STRENGTH OF DIFFERENT PIGS GENETIC TYPES [PDF]

, 2010
The aim of this study was to evaluate the bone strength in different genetic types of pigs. Nowadays, in swine production it is rather common to obtain pigs with weak bones, especially on the hind legs.
Griggio, Michele
core  

Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues

Advanced Materials Interfaces, EarlyView.
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike, Dhananjay V. Deshmukh, Mark W. Tibbitt, Céline Labouesse   +3 more
wiley   +1 more source