Results 111 to 120 of about 217,854 (311)

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta, Myoung Joon Jeon, Youjin Seol, Ki‐Taek Lim   +3 more
wiley   +1 more source

Research progress on the regulation and mechanism of osteocytes on osteoblasts and osteoclasts

Kouqiang hemian waike zazhi
With the continuous explorations and researches of osteocytes, osteocytes are no longer mistaken for a kind of quiescent and passive cells, but active and positive cells, which play important regulatory roles in osteoblasts and osteoclasts.
YANG Zhenming, ZHANG Shuyu, QIANG Jinbiao, SHI Yan, WANG Xiaoling, SHI Ce   +5 more
doaj   +1 more source

Poromechanical stimulation of bone remodeling: A continuum micromechanics-based mathematical model and experimental validation

, 2013
Bone tissue is a living biological entity. In particular, it is able to renew itself, which is key for maintaining its mechanical integrity necessary for fulfilling fundamental tasks such as providing protection of organs and facilitating locomotion ...
Pivonka, P., Scheiner, S., Stefan Scheiner, Hellmich, C., Peter Pivonka, Christian Hellmich   +5 more
core   +1 more source

Tracking Spatiotemporal Extracellular Matrix Evolution and Tissue Fusion in 3D Microtissues via Click Chemistry‐Based Metabolic Labelling

Advanced Healthcare Materials, EarlyView.
Metabolic labeling of nascent proteins in 3D microtissue spheroids provides a powerful analytical approach for large‐scale tissue engineering. Incorporation of non‐canonical amino acids with fluorescent tagging enables spatiotemporal investigation of extracellular matrix deposition and its evolution during multicellular tissue development and fusion ...
Theresa Koenig, F. Max Yavitt, Laura Veenendaal, Tim B. F. Woodfield   +3 more
wiley   +1 more source

Mesalazine: a novel therapeutic agent for periodontitis via regulation of periodontal microbiota and inhibiting Porphyromonas gingivalis

Frontiers in Microbiology
IntroductionPeriodontitis and inflammatory bowel disease are chronic inflammatory diseases with shared epidemiological, biological, and therapeutic associations. Given the similarities in their pathogenic factors, this study hypothesized that mesalazine,
Yuqi Wang, Yuqi Wang, Jun Ma, Haoyu Wang, Haoyu Wang, Jingzheng Yi, Yuxin Bai, Yuxin Bai, Min Hu, Min Hu, Jiaqing Yan, Jiaqing Yan   +11 more
doaj   +1 more source

Bone Remodeling

, 2014
Skeletal buildup and maintenance is ensured by modeling and remodeling processes. Bone modeling works mainly during organism growth and is characterized by bone formation prevailing on resorption: The two processes are carried out simultaneously but not ...
Giacomina Brunetti, Adriana Di Benedetto, Brunetti G., DI BENEDETTO, ADRIANA, MORI, GIORGIO, BRUNETTI, GIACOMINA, MORI G., Giorgio Mori, DI BENEDETTO A   +8 more
core   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Osteogenic mechanism of chlorogenic acid and its application in clinical practice

Frontiers in Pharmacology
Natural polyphenols may have a role in counteracting oxidative stress, which is associated with aging and several bone-related diseases. Chlorogenic acid (CGA) is a naturally occurring polyphenolic compound formed by the esterification of caffeic and ...
Jiayu Shen, Jiayu Shen, Shichen Zhang, Shichen Zhang, Jiayu Zhang, Jiayu Zhang, Xin Wei, Xin Wei, Zilin Wang, Zilin Wang, Bing Han, Bing Han   +11 more
doaj   +1 more source

pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women

, 2013
In a pQCT study of running-trained and untrained men and women we had shown that bone mass distribution along the tibia was adapted to the usage-derived stress pattern.
Rittweger, Jörn, Mortarino, Pablo, Feldman, Sara, Reina, P. S., Cointry, Gustavo, Capozza, R. F., Nocciolino, L. M., Ferretti, José Luis   +7 more
core  

Knee loading protects against osteonecrosis of the femoral head by enhancing vessel remodeling and bone healing

, 2015
Osteonecrosis of the femoral head is a serious orthopedic problem. Moderate loads with knee loading promote bone formation, but their effects on osteonecrosis have not been investigated.
Liu, Daquan, Li, Xinle, Li, Jie, Yokota, Hiroki, Yang, Jing, Zhang, Ping   +5 more
core   +1 more source