Results 101 to 110 of about 209,372 (314)

An Ion‐Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR‐Mediated Antibacterial Activity of PEEK

Advanced Materials, EarlyView.
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu, Ondřej Adam, Marek Doubrava, Ana M. Beltrán, Ivo Dlouhý, Xin Liu, Baiyan Sui, Aldo R. Boccaccini   +7 more
wiley   +1 more source

Fibroblast–immune crosstalk in oral squamous cell carcinoma: from tumor promotion to immune evasion

Frontiers in Immunology
Oral squamous cell carcinoma (OSCC) is a highly invasive malignancy marked by poor prognosis and therapeutic resistance. Within its tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) and immune cells form a dynamic network that drives ...
Xiao Liu, Xiao Liu, Dandan Wang, Dandan Wang, Xue Cheng, Xue Cheng, Yining Ma, Yining Ma, Siya Li, Jinhai Deng, Chunyan Qiao, Chunyan Qiao   +11 more
doaj   +1 more source

Mechanisms of bone remodeling and therapeutic strategies in chronic apical periodontitis [PDF]

, 2022
Xutao Luo, Qianxue Wan, Lei Cheng, Ruoshi Xu   +3 more
openalex   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Reply to “Letter to the Editor Concerning ‘Trabecular Bone Remodeling as a New Indicator of Osteointegration After Posterior Lumbar Interbody Fusion.’ by Segi et al.”

, 2023
Naoki Segi, Hiroaki Nakashima, Ryuichi Shinjo, Yujiro Kagami, Masaaki Machino, Sadayuki Ito, Jun Ouchida, Shiro Imagama   +7 more
openalex   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Cell membrane biomimetic nanoplatforms: a new strategy for immune escape and precision targeted therapy

Materials Today Bio
Cell membrane biomimetic nanoplatforms represent an innovative approach to addressing key challenges in nanodrug delivery systems by encapsulating natural cell membranes onto nanomaterials. This strategy confers unique biological properties that overcome
Jian Feng, Dixin He, Jingxia Chen, Mucong Li, Jiaxin Luo, Yuzhu Han, Xuyan Wei, Sicong Ren, Zhibo Wang, Yunxiao Wu, Hanchi Wang, Yidi Zhang, Yanmin Zhou   +12 more
doaj   +1 more source

Fractures in regions of adaptive modeling and remodeling of central tarsal bones in racing Greyhounds [PDF]

, 2012
Mary Sarah Bergh, Alessandro Piras, Valerie F. Samii, Steven E. Weisbrode, Kenneth A. Johnson   +4 more
openalex   +1 more source

Dynamic Mechanical Loading Modulates Extracellular Vesicle Production and Cargo in Meniscus Fibrochondrocytes

Advanced Materials Interfaces, EarlyView.
Dynamic mechanical loading of outer meniscus fibrochondrocytes increases extracellular vesicle (EV) yield and alters EV composition. When applied to progenitor cells, these mechanically primed EVs modulate the expression of matrix‐related genes.
Catherine Cheung, Zizhao Li, Sung‐Han Jo, Se‐Hwan Lee, Il Keun Kwon, Jina Ko, Su Chin Heo   +6 more
wiley   +1 more source

Molecular profiling of bone remodeling occurring in musculoskeletal tumors [PDF]

, 2020
Kosei Nakajima, Teruki Kidani, Hiromasa Miura   +2 more
openalex   +1 more source