Results 101 to 110 of about 1,336,774 (305)

Interleukin‐18 expression in oral squamous cell carcinoma: its role in tumor cell migration and invasion, and growth of tumor cell xenografts

FEBS Open Bio, 2018
Oral squamous cell carcinoma (OSCC) is one of the most common head and neck malignancies. Advanced stages of the disease are associated with poor survival, highlighting a need for new treatment modalities.
Yuyang Li, Zhiming Xu, Jia Li, Shuofeng Ban, Congcong Duan, Weiwei Liu   +5 more
doaj   +1 more source

CALCIUM, BONE REMODELING AND SKELETAL QUALITY

, 2012
The degree of mineralization of bone tissue is an important determinant of bone strength and bone mineral density (BMD) and is influenced by changes in bone remodeling.
, Tecky Indriana
core  

Bone functional remodeling under multi-field loadings [PDF]

, 2007
Bone remodeling process is investigated theoretically and numerically within the framework of the extended adaptive elasticity. The coupling between the internal and surface remodeling is considered for the solution of the bone remodeling process. A semi-
Qin, Qing-Hua, He, Xiaoqiao, Qu, Chuanyong   +2 more
core  

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

Advances in amino acid metabolism in bone remodeling and osteoporosis

Kouqiang hemian waike zazhi
Bone is a metabolically active organ that undergoes continuous bone remodeling throughout life to maintain bone homeostasis. Amino acids are the basic units of proteins, which play an important role in the regulation of material metabolism and ...
ZHANG Shuyu, YANG Zhenming, QIANG Jinbiao, SHI Ce   +3 more
doaj   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source

Intramembranous and endochondral bone remodeling upon maxillary protraction.

, 2004
Intramembranous and endochondral bone remodeling upon maxillary ...
Xin. Wang (7960196)
core   +4 more sources

A Blood‐Derived Double‐Network Hydrogel with Robust Wet Adhesion for Keratinized Mucosa Regeneration via Neutrophil Phenotype Reprogramming and Mechanophysical Niche Modulation

Advanced Science
Reconstruction of keratinized mucosa (KM) with sufficient dimensions is critical for long‐term periodontal and peri‐implant health. However, existing biomaterials struggle to recapitulate the complex biophysical and biochemical microenvironment of KM ...
Sicong Ren, Xinting Yang, Jingxia Chen, Yihan Wang, Jian Feng, Jing Zhou, Jiaxin Luo, Jingjie Zhai, Quan Lin, Yanmin Zhou   +9 more
doaj   +1 more source