Results 81 to 90 of about 1,336,774 (305)

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

Advanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur, Minye Jin, Pavel Milkin, Deepa Negi, Carla Cofiño Fabres, Hubert Gojzewski, Leonid Ionov, Alla Synytska, Andries van der Meer, Robert Passier, Julieta I. Paez   +10 more
wiley   +1 more source

Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells

Kouqiang hemian waike zazhi
The role of bone marrow mesenchymal stem cells (BMSCs) in bone defect repair and bone regeneration has been extensively studied. Much evidence suggests that effective endogenous bone regeneration requires coordination of the immune system.
SHI Yan, GUO Hao, ZHENG Kaijuan, YANG Zhenming, QIANG Jinbiao, SHI Ce   +5 more
doaj   +1 more source

Mechanisms of Altered Bone Remodeling in Multiple Myeloma

, 2017
Multiple myeloma (MM) is a hematologic malignancy of plasma cells proliferating in the bone marrow and it is associated with the osteolytic bone disease.
Giacomina Brunetti, Silvia Colucci, Brunetti, Giacomina, Colaianni, Graziana, Faienza, Maria Felicia, Maria Felicia Faienza, Grano, Maria, Maria Grano, Colucci, Silvia, Graziana Colaianni   +9 more
core   +1 more source

New aspects of spondyloarthritis pathogenesis. Part III – arthritis, pathological bone remodeling [PDF]

, 2014
Spondyloarthritis (SpA) is a form of chronic inflammatory arthritis affecting axial and peripheral joints, which may be initiated by inflammation of joint subchondral bone marrow or enthesitis.
Ewa Kontny
core   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source

Bone remodeling in post-menopausal osteoporosis

, 2006
Bone mass in the skeleton is dependent on the coordinated activities of bone-forming osteoblasts and bone-resorbing osteoclasts in discrete bone multi-cellular units.
Lerner, Ulf H,
core   +2 more sources

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

Interpretation of the WHO 2022 classification of head and neck tumours (5th Edition): The epithelial tumours of oral cavity and mobile tongue

Kouqiang hemian waike zazhi
The 5th edition of the Classification of Head and Neck Tumours by the World Health Organization (WHO) was published in March 2022. In the section on oral cavity and mobile tongue tumours, the classification of epithelial tumours in the 5th edition has ...
LI Jinwei, SHA Tong, ZHENG Kaijuan, NIE Mengdong, GUAN Weihang, SHI Ce   +5 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Dual-Action flavonol carbonized polymer dots spray: Accelerating burn wound recovery through immune responses modulation and EMT induction

Materials Today Bio
Effective immune homeostasis modulation and re-epithelialization promotion are crucial for accelerating burn wound healing. Cell migration is fundamental to re-epithelialization, with epithelial-mesenchymal transition (EMT) as a key mechanism.
Liuyi Du, Xu Zhang, Lei Huang, Mingxi Yang, Wenbin Zhang, Jiaqi Xu, Junguang Liu, Wangni Xie, Xue Zhang, Kexuan Liu, Wenhao Zhai, Linlin Wen, Boya Zhang, Rongrong Ye, Lijun Liu, Huan Wang, Hongchen Sun, Daowei Li   +17 more
doaj   +1 more source