Results 141 to 150 of about 2,247,449 (357)
Bisphosphonates impair the onset of bone formation at remodeling sites
, 2021 Pia Rosgaard Jensen +4 more
openalex +1 more source
Deubiquitinating Enzymes and Bone Remodeling
Stem Cells International, 2018 Bone remodeling, which is essential for bone homeostasis, is controlled by multiple factors and mechanisms. In the past few years, studies have emphasized the role of the ubiquitin-dependent proteolysis system in regulating bone remodeling ...
Yuchen Guo, Shiwen Zhang, Q. Yuan
semanticscholar +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Materials Today BioWound infection is a serious clinical challenge, often accompanied by persistent inflammatory response and the threat of increased bacterial resistance, there is an urgent requirement to develop a wound dressing with potent antimicrobial as well as ...
Shaobo Zhai +10 more
doaj +1 more source
FEBS Open Bio, 2018 Oral squamous cell carcinoma (OSCC) is one of the most common head and neck malignancies. Advanced stages of the disease are associated with poor survival, highlighting a need for new treatment modalities.
Yuyang Li +5 more
doaj +1 more source
Topography‐Supported Nanoarchitectonics of Hybrid Scaffold for Systematically Modulated Bone Regeneration and Remodeling [PDF]
, 2022 Tae‐Sik Jang +15 more
openalex +1 more source
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
Old age causes de novo intracortical bone remodeling and porosity in mice.
JCI Insight, 2017 Decreased cortical thickness and increased cortical porosity are the key anatomic changes responsible for osteoporotic fractures in elderly women and men.
M. Piemontese +9 more
semanticscholar +1 more source
Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
Advanced Functional Materials, EarlyView.Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt +2 more
wiley +1 more source
Advances in amino acid metabolism in bone remodeling and osteoporosis
Kouqiang hemian waike zazhiBone is a metabolically active organ that undergoes continuous bone remodeling throughout life to maintain bone homeostasis. Amino acids are the basic units of proteins, which play an important role in the regulation of material metabolism and ...
ZHANG Shuyu +3 more
doaj +1 more source