Results 151 to 160 of about 338,869 (357)
Periprosthetic bone remodelling around a prosthesis for distal femoral tumours [PDF]
Fang Lan+7 more
openalex +1 more source
This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret+4 more
wiley +1 more source
Computer predictions of bone remodeling around porous-coated implants
Tracy E. Orr+3 more
openalex +1 more source
A 3D‐printed PCL scaffold coated with Arginine was laminated with electrospun polyvinyl alcohol (PVA) nanofibers containing cationic cellulose nanocrystals (PVA@cCNC). This created nanoisland‐like regions of aligned and random cCNC‐rich fibers. The composite scaffold, under fluid shear stimulation, modulated macrophage polarization from M1 to M2 ...
Keya Ganguly+8 more
wiley +1 more source
A H2-bioreactor for mitochondrial rehabilitation in infected bone defects regeneration
The repair of infected bone defects (IBDs) presents a significant clinical challenge due to recurrent infections and inflammation. Characterized by reactive oxygen species (ROS) bursts and mitochondrial dysfunction, IBDs generates to a vicious oxidation ...
Chunru Kong+8 more
doaj +1 more source
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han+7 more
wiley +1 more source
Alteration of Mechanical Properties of Remodeling Bone Adapted to Mechanical Stimuli.
K. Kurata+4 more
openalex +4 more sources
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex+4 more
wiley +1 more source