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The bone remodelling cycle [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2018
The bone remodelling cycle replaces old and damaged bone and is a highly regulated, lifelong process essential for preserving bone integrity and maintaining mineral homeostasis. During the bone remodelling cycle, osteoclastic resorption is tightly coupled to osteoblastic bone formation.
JS Kenkre, JHD Bassett
openaire   +5 more sources

Apoptotic mesenchymal stromal cells support osteoclastogenesis while inhibiting multinucleated giant cells formation in vitro

Scientific Reports, 2021
In bone regeneration induced by the combination of mesenchymal stromal cells (MSCs) and calcium-phosphate (CaP) materials, osteoclasts emerge as a pivotal cell linking inflammation and bone formation.
Paul Humbert, Meadhbh Á. Brennan, Julien De Lima, Régis Brion, Annie Adrait, Céline Charrier, Bénédicte Brulin, Valérie Trichet, Yohann Couté, Frédéric Blanchard, Pierre Layrolle   +10 more
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Synthesis and Characterization of a Hydroxyapatite-Sodium Alginate-Chitosan Scaffold for Bone Regeneration

Frontiers in Materials, 2021
Bone scaffolds play an important role in promoting the healing of large bone defects. However, the type of scaffold material, type of drug loaded into the scaffold, and method of preparation have a significant impact on the scaffold's properties. In this
Dingkun Liu, Dingkun Liu, Zhihui Liu, Jundong Zou, Lingfeng Li, Xin Sui, Bizhou Wang, Nan Yang, Bowei Wang   +8 more
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Antibacterial properties of antimicrobial peptide HHC36 modified polyetheretherketone

Frontiers in Microbiology, 2023
IntroductionPolyetheretherketone (PEEK) is considered to be a new type of orthopedic implant material due to its mechanical properties and biocompatibility.
Weijia Gao, Xiao Han, Duo Sun, Yongli Li, Xiaoli Liu, Shihui Yang, Zhe Zhou, Yuanzheng Qi, Junjie Jiao, Jinghui Zhao   +9 more
doaj   +1 more source

SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression

Cells, 2020
Primary bone tumors can be divided into two classes, benign and malignant. Among the latter group, osteosarcoma and Ewing sarcoma are the most prevalent malignant primary bone tumors in children and adolescents.
Frédéric Lézot, Isabelle Corre, Sarah Morice, Françoise Rédini, Franck Verrecchia   +4 more
doaj   +1 more source

Chitosan as a biomaterial for the prevention and treatment of dental caries: antibacterial effect, biomimetic mineralization, and drug delivery

Frontiers in Bioengineering and Biotechnology, 2023
Dental caries is a chronic, progressive disease caused by plaque, influenced by multiple factors and can damage the hard tissues of the teeth. In severe cases, it can also lead to the onset and development of other oral diseases, seriously affecting ...
Shanlin Qu, Shanlin Qu, Xiaolin Ma, Xiaolin Ma, Shuo Yu, Shuo Yu, Rui Wang, Rui Wang   +7 more
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Ribosomopathies: New Therapeutic Perspectives

Cells, 2020
Ribosomopathies are a group of rare diseases in which genetic mutations cause defects in either ribosome biogenesis or function, given specific phenotypes.
Emilien Orgebin, François Lamoureux, Bertrand Isidor, Céline Charrier, Benjamin Ory, Frédéric Lézot, Marc Baud’huin   +6 more
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“Medicine food homology” plants promote periodontal health: antimicrobial, anti-inflammatory, and inhibition of bone resorption

Frontiers in Nutrition, 2023
“Medicine food homology” (MFH) is a term with a lengthy history. It refers to the fact that a lot of traditional natural products have both culinary and therapeutic benefits.
Shanlin Qu, Shanlin Qu, Shuo Yu, Shuo Yu, Xiaolin Ma, Xiaolin Ma, Rui Wang, Rui Wang   +7 more
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The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem

Cells, 2020
Osteosarcomas are the most frequent primary bone sarcomas, affecting mainly children, adolescents, and young adults, and with a second peak of incidence in elderly individuals.
Isabelle Corre, Franck Verrecchia, Vincent Crenn, Francoise Redini, Valérie Trichet   +4 more
doaj   +1 more source

Experimental study of dexamethasone-loaded hollow hydroxyapatite microspheres applied to direct pulp capping of rat molars

Frontiers in Endocrinology, 2023
BackgroundDexamethasone (DEX) exerts anti-inflammatory and osteogenic effects. Hydroxyapatite is commonly used in bone repair due to its osteoconductivity, osseointegration, and osteogenesis induction. Hollow hydroxyapatite (HHAM) is often used as a drug
Xiaoli Liu, Yuandong Xie, Weijia Gao, Luoning Zhan, Ling Hu, Linjing Zuo, Yi Li   +6 more
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