Results 11 to 20 of about 1,873,821 (213)
Genetics and Epigenetics of Bone Remodeling and Metabolic Bone Diseases
International Journal of Molecular Sciences, 2022 Bone metabolism consists of a balance between bone formation and bone resorption, which is mediated by osteoblast and osteoclast activity, respectively.
L. Otòn-Gonzalez +9 more
semanticscholar +1 more source
Autophagy in Bone Remodeling: A Regulator of Oxidative Stress
Frontiers in Endocrinology, 2022 Bone homeostasis involves bone formation and bone resorption, which are processes that maintain skeletal health. Oxidative stress is an independent risk factor, causing the dysfunction of bone homeostasis including osteoblast-induced osteogenesis and ...
Chenyu Zhu +5 more
semanticscholar +1 more source
Subchondral Bone Remodeling: A Therapeutic Target for Osteoarthritis
Frontiers in Cell and Developmental Biology, 2021 There is emerging awareness that subchondral bone remodeling plays an important role in the development of osteoarthritis (OA). This review presents recent investigations on the cellular and molecular mechanism of subchondral bone remodeling, and ...
Xiaobo Zhu +4 more
semanticscholar +1 more source
Trabecular bone organoid model for studying the regulation of localized bone remodeling
Science Advances, 2021 A tissue-engineered model of the trabecular bone microenvironment elucidates spatiotemporal aspects of bone remodeling processes. Trabecular bone maintains physiological homeostasis and consistent structure and mass through repeated cycles of bone ...
Yongkuk Park +5 more
semanticscholar +1 more source
Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling
Bone Research, 2021 Bone remodeling is precisely coordinated by bone resorption and formation. Apoptotic osteoclasts generate large amounts of apoptotic bodies (ABs) marking the end of the bone resorption phase, whereas the functions of osteoclast-derived ABs remain largely
Qinyu Ma +7 more
semanticscholar +1 more source
RANKL/RANK/OPG Pathway: A Mechanism Involved in Exercise-Induced Bone Remodeling
BioMed Research International, 2020 Bones as an alive organ consist of about 70% mineral and 30% organic component. About 200 million people are suffering from osteopenia and osteoporosis around the world.
Mohammad Tobeiha +3 more
semanticscholar +1 more source
Communications Between Bone Marrow Macrophages and Bone Cells in Bone Remodeling
Frontiers in Cell and Developmental Biology, 2020 The mammalian skeleton is a metabolically active organ that continuously undergoes bone remodeling, a process of tightly coupled bone resorption and formation throughout life.
Kaixuan Chen +9 more
semanticscholar +1 more source
Type H blood vessels in bone modeling and remodeling
Theranostics, 2020 In the mammalian skeletal system, osteogenesis and angiogenesis are intimately linked during bone growth and regeneration in bone modeling and during bone homeostasis in bone remodeling.
Yi Peng +3 more
semanticscholar +1 more source
Journal of Bone and Mineral Research, 2020 Osteoarthritis (OA) and osteoporosis (OP) are two skeletal disorders associated with joint structures. Occasionally, OA and OP occur in the same patient. However, the effect of OP changes on OA progression in patients with osteoporotic OA (OP‐OA) has not
L. Chu +7 more
semanticscholar +1 more source
Oxidative stress in bone remodeling: role of antioxidants.
CLINICAL CASES IN MINERAL AND BONE METABOLISM, 2017 ROS are highly reactive molecules which consist of a number of diverse chemical species, including radical and non-radical oxygen species. Oxidative stress occurs as a result of an overproduction of ROS not balanced by an adequate level of antioxidants ...
Vladana Domazetovic +4 more
semanticscholar +1 more source