Results 11 to 20 of about 2,011,561 (382)

Bone Remodeling and the Microbiome. [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2018
Exposed surfaces of mammals are colonized with 100 trillion indigenous bacteria, fungi, and viruses, creating a diverse ecosystem known as the microbiome.
R. Pacifici
semanticscholar   +3 more sources

Deubiquitinating Enzymes and Bone Remodeling [PDF]

open access: yesStem Cells International, 2018
Bone remodeling, which is essential for bone homeostasis, is controlled by multiple factors and mechanisms. In the past few years, studies have emphasized the role of the ubiquitin-dependent proteolysis system in regulating bone remodeling ...
Yuchen Guo, Shiwen Zhang, Q. Yuan
semanticscholar   +5 more sources

Roles of osteoclasts in alveolar bone remodeling

open access: yesGenesis, 2022
Osteoclasts are large multinucleated cells from hematopoietic origin and are responsible for bone resorption. A balance between osteoclastic bone resorption and osteoblastic bone formation is critical to maintain bone homeostasis. The alveolar bone, also
Maiko Omi, Y. Mishina
semanticscholar   +1 more source

Pro-inflammatory effects of human apatite crystals extracted from patients suffering from calcific tendinopathy

open access: yesArthritis Research & Therapy, 2021
Background Calcific tendonitis of the rotator cuff is due to carbonated apatite deposits in the shoulder tendons. During the evolution of the disease, an acute inflammatory episode may occur leading to the disappearance of the calcification.
Julien Herman   +6 more
doaj   +1 more source

Genetics and Epigenetics of Bone Remodeling and Metabolic Bone Diseases

open access: yesInternational Journal of Molecular Sciences, 2022
Bone metabolism consists of a balance between bone formation and bone resorption, which is mediated by osteoblast and osteoclast activity, respectively.
L. Otòn-Gonzalez   +9 more
semanticscholar   +1 more source

Simulating pharmaceutical treatment effects on osteoporosis via a bone remodeling algorithm targeting hypermineralized sites [PDF]

open access: yesMedical Engineering and Physics, Elsevier, 2020, 76, pp.56 - 68, 2021
Pharmaceutical treatments can slow bone degradation, thus reducing the fracture risk inherent in osteoporosis. Antiresorptive treatments block the over-activation of osteoclasts vs osteoblasts, but the resulting decrease in bone remodeling frequency may weaken bone structure over time, with no gain in bone volume.
arxiv   +1 more source

The Role Of BMPs in the Regulation of Osteoclasts Resorption and Bone Remodeling: From Experimental Models to Clinical Applications

open access: yesFrontiers in Immunology, 2022
In response to mechanical forces and the aging process, bone in the adult skeleton is continuously remodeled by a process in which old and damaged bone is removed by bone-resorbing osteoclasts and subsequently is replaced by new bone by bone-forming ...
T. Bordukalo-Nikšić   +2 more
semanticscholar   +1 more source

Autophagy in Bone Remodeling: A Regulator of Oxidative Stress

open access: yesFrontiers in Endocrinology, 2022
Bone homeostasis involves bone formation and bone resorption, which are processes that maintain skeletal health. Oxidative stress is an independent risk factor, causing the dysfunction of bone homeostasis including osteoblast-induced osteogenesis and ...
Chenyu Zhu   +5 more
semanticscholar   +1 more source

The bone remodelling cycle [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2018
The bone remodelling cycle replaces old and damaged bone and is a highly regulated, lifelong process essential for preserving bone integrity and maintaining mineral homeostasis. During the bone remodelling cycle, osteoclastic resorption is tightly coupled to osteoblastic bone formation.
JS Kenkre, JHD Bassett
openaire   +5 more sources

Advances of exosomes in periodontitis treatment

open access: yesJournal of Translational Medicine, 2022
Periodontitis is an inflammatory disease initiated by dysbiosis of the local microbial community. Periodontitis can result in destruction of tooth-supporting tissue; however, overactivation of the host immune response is the main reason for alveolar bone
Hongbing Lin   +8 more
doaj   +1 more source

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