Results 21 to 30 of about 2,011,561 (382)
Subchondral Bone Remodeling: A Therapeutic Target for Osteoarthritis
Frontiers in Cell and Developmental Biology, 2021 There is emerging awareness that subchondral bone remodeling plays an important role in the development of osteoarthritis (OA). This review presents recent investigations on the cellular and molecular mechanism of subchondral bone remodeling, and ...
Xiaobo Zhu +4 more
semanticscholar +1 more source
Trabecular bone organoid model for studying the regulation of localized bone remodeling
Science Advances, 2021 A tissue-engineered model of the trabecular bone microenvironment elucidates spatiotemporal aspects of bone remodeling processes. Trabecular bone maintains physiological homeostasis and consistent structure and mass through repeated cycles of bone ...
Yongkuk Park +5 more
semanticscholar +1 more source
Effects of chronic stress caused by occlusal disorder on the body
口腔疾病防治, 2020 Occlusal disorder is an abnormal condition in which the static and dynamic relations between the upper and lower teeth are not well aligned . The most common occlusal disorder in clinical practice is the inability to reach the intercuspal position due to
JIANG Jiayang +6 more
doaj +1 more source
The impact of masticatory dysfunction caused by occlusal disharmony on cognitive function
口腔疾病防治, 2021 As the world’s population ages, age-related cognitive decline and dementia are becoming important challenges for geriatric care. Despite the ongoing search for solutions to address cognitive decline, effective interventions have not yet been established.
OU Yanzhen +5 more
doaj +1 more source
Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling
Bone Research, 2021 Bone remodeling is precisely coordinated by bone resorption and formation. Apoptotic osteoclasts generate large amounts of apoptotic bodies (ABs) marking the end of the bone resorption phase, whereas the functions of osteoclast-derived ABs remain largely
Qinyu Ma +7 more
semanticscholar +1 more source
Cells, 2020 The formation of the skeleton occurs throughout the lives of vertebrates and is achieved through the balanced activities of two kinds of specialized bone cells: the bone-forming osteoblasts and the bone-resorbing osteoclasts. Impairment in the remodeling
Camille Jacques +6 more
doaj +1 more source
Frontiers in Materials, 2021 Bone scaffolds play an important role in promoting the healing of large bone defects. However, the type of scaffold material, type of drug loaded into the scaffold, and method of preparation have a significant impact on the scaffold's properties. In this
Dingkun Liu +8 more
doaj +1 more source
Epigenetics and Bone Remodeling [PDF]
Current Osteoporosis Reports, 2017 Bone remodeling is a diverse field of study with many direct clinical applications; past studies have implicated epigenetic alterations as key factors of both normal bone tissue development and function and diseases of pathologic bone remodeling. The purpose of this article is to review the most important recent advances that link epigenetic changes to
A. Husain, M. Jeffries
semanticscholar +4 more sources
Current Osteoporosis Reports, 2017 The mechanisms involved in the TNF-mediated deregulated bone remodeling are little appreciated. This review will discuss and summarize the impact of TNF, Notch, and RBP-J signaling on bone remodeling.The integrity of the adult skeleton undergoes constant and dynamic remodeling throughout life to maintain a proper bone homeostasis, which is achieved by ...
Baohong Zhao
semanticscholar +4 more sources
Scientific Reports, 2021 In bone regeneration induced by the combination of mesenchymal stromal cells (MSCs) and calcium-phosphate (CaP) materials, osteoclasts emerge as a pivotal cell linking inflammation and bone formation.
Paul Humbert +10 more
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