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Disorders of Bone Remodeling [PDF]
Annual Review of Pathology: Mechanisms of Disease, 2011 The skeleton provides mechanical support for stature and locomotion, protects vital organs, and controls mineral homeostasis. A healthy skeleton must be maintained by constant bone modeling to carry out these crucial functions throughout life. Bone remodeling involves the removal of old or damaged bone by osteoclasts (bone resorption) and the ...
Jay M. McDonald, Xu Feng
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Epigenetics and Bone Remodeling [PDF]
Current Osteoporosis Reports, 2017 Bone remodeling is a diverse field of study with many direct clinical applications; past studies have implicated epigenetic alterations as key factors of both normal bone tissue development and function and diseases of pathologic bone remodeling. The purpose of this article is to review the most important recent advances that link epigenetic changes to
Matlock A. Jeffries, Ali Husain
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Frontiers in Endocrinology, 2015 The 3D arrangement of porous granular biomaterials usable to fill bone defects has received little study. Granular biomaterials occupy 3D space when packed together in a manner that creates a porosity suitable for the invasion of vascular and bone cells.
Daniel eCHAPPARD +6 more
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Tiludronate and clodronate do not affect bone structure or remodeling kinetics over a 60 day randomized trial [PDF]
, 2018 Background Tiludronate and clodronate are FDA-approved bisphosphonate drug therapies for navicular disease in horses. Although clinical studies have determined their ability to reduce lameness associated with skeletal disorders in horses, data regarding
Gillett, Ashley N. +3 more
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Chemokines and Bone Remodeling
International Journal of Immunopathology and Pharmacology, 2008 Bone remodeling is characterized by spatial and temporal coupling of bone resorption and formation and is necessary for skeletal growth and normal bone structure maintenance. Imbalance of this process is related to metabolic bone disorders such as osteoporosis or rheumatoid arthritis.
E. Galliera +3 more
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Towards a New Spatial Representation of Bone Remodeling [PDF]
, 2012 Irregular bone remodeling is associated with a number of bone diseases such as osteoporosis and multiple myeloma. Computational and mathematical modeling can aid in therapy and treatment as well as understanding fundamental biology.
Ayati, Bruce P. +3 more
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Electronic Notes in Theoretical Computer Science, 2010 AbstractMany biological phenomena are inherently multiscale, i.e. they are characterised by interactions involving different scales at the same time. This is the case of bone remodelling, where macroscopic behaviour (at organ and tissue scale) and microstructure (at cell scale) strongly influence each other.
BUTI, Federico +5 more
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Remodeling Of The Bone Tissue Of Rats Of Different Lines After Melatonin Effect [PDF]
, 2016 The markers of remodeling of bone tissue (BT) were studied after the impact of pharmacologic dose of melatonin (5 mg/kg of the animal body weight) during 28 days for 3-months rats-males of Wistar and SHR lines.
Berezovskyi, V. (Vadim) +2 more
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Kouqiang hemian waike zazhi, 2023 [Objective:] To make a clinicopathological analysis of human papilloma virus (HPV)‐related and non‐HPV‐related oral/oropharyngeal squamous cell carcinoma (OSCC/OPSCC) diagnosed in our hospital, and to further understand the differences between the two ...
WANG Xiaoling +6 more
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Immunoregulation of bone remodelling
International Journal of Critical Illness and Injury Science, 2012 Remodeling, a continuous physiological process maintains the strength of the bones, which maintains a delicate balance between bone formation and resorption process. This review gives an insight to the complex interaction and correlation between the bone remodeling and the corresponding changes in host immunological environment and also summarises the ...
Ajai Singh +3 more
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