Results 291 to 300 of about 2,265,392 (399)

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Denosumab treatment of osteoporotic women arrests cortical bone remodeling events at the reversal-resorption phase but does not affect ongoing bone formation. [PDF]

JBMR Plus
Dahl XG, Roux JP, Delaisse JM, Huang S, Chavassieux P, Andreasen CM, Andersen TL.   +6 more
europepmc   +1 more source

Bone Remodeling and the Microbiome.

Cold Spring Harbor Perspectives in Medicine, 2018
R. Pacifici
semanticscholar   +1 more source

TREM2‐Mediated Cholesterol Efflux in Macrophages Inhibits Anti‐Tumor Immunity via Limitation of CD4+ T and NK Cells

Advanced Science, EarlyView.
Impaired anti‐tumor immunity is mediated by TREM2 + macrophages in non‐small cell lung cancer. TREM2 + macrophages prevent anti‐tumor immunity depending on the limitation of CD4 + T and NK cells. TREM2 promotes cholesterol efflux via ABCA1 to limit the production of CX3CL1 in macrophages.
Yunhan Wang, Weina Yu, Xinxin Wang, Qitai Zhao, Qingyang Lei, Aitian Li, Shasha Liu, Tian Wang, Li Yang, Yi Zhang   +9 more
wiley   +1 more source

Hydrothermal Magnesium Alloy Extracts Modulate MicroRNA Expression in RAW264.7 Cells: Implications for Bone Remodeling. [PDF]

J Funct Biomater
Costa V, Raimondi L, Bellavia D, De Luca A, Guglielmi P, Cusanno A, Cattini L, Pulsatelli L, Pavarini M, Chiesa R, Giavaresi G.   +10 more
europepmc   +1 more source

Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement.

Physiology, 2016
J. Siddiqui, N. Partridge
semanticscholar   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Bone remodeling stimulated by Wnt-mediated mitophagy regulated extracellular vesicles in subchondral bone contributes to osteoarthritis development. [PDF]

Theranostics
Gu Y, Zhou Q, Sheng S, Yang H, Huang D, Zhang Q, Zhang H, Cao Z, Zhang Y, Li Z, Jiang Y, Chen X, Jing Y, Wang C, Tan H, Xu K, Su J.   +16 more
europepmc   +1 more source

BMD, CTX-1, and Osteocalcin as Monitoring Parameters of Bone Remodelling in CML Patients Undergoing Imatinib Therapy: From Basic Science to Clinical Perspective

Nurita Indarwulan, Merlyna Savitri, Ami Ashariati, Ugroseno Yudho Bintoro, Muhammad Noor Diansyah, Putu Niken Ayu Amrita, Pradana Zaky Romadhon   +6 more
openalex   +2 more sources

Regulation of bone remodeling by vitamin K2.

Oral Diseases, 2017
Vamsee D. Myneni, É. Mezey
semanticscholar   +1 more source