Results 291 to 300 of about 2,011,561 (382)

Tracking of spaceflight-induced bone remodeling reveals a limited time frame for recovery of resorption sites in humans. [PDF]

open access: yesSci Adv
Walle M   +9 more
europepmc   +1 more source

Camouflaged Nanozymes with Oxidation‐Promoting Activities Triggering Ferroptosis for Radio‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study develops a cancer cell membrane‐coated nanozyme that enhances radiotherapy and reshapes the immunosuppressive microenvironment by generating oxygen in situ and disrupting tumor antioxidant defenses, offering a new strategy for breast cancer radioimmunotherapy.
Kun Qiao   +11 more
wiley   +1 more source

Targeting PFKFB4 Biomimetic Codelivery System Synergistically Enhances Ferroptosis to Suppress Small Cell Lung Cancer and Augments the Efficacy of Anti‐PD‐L1 Immunotherapy

open access: yesAdvanced Science, EarlyView.
In this study, a targeting PFKFB4 biomimetic codelivery system is developed to improve paclitaxel efficacy by inducing ferroptosis in SCLC. This system enhances immune cell infiltration and cytokine secretion, activating anti‐tumor immunity. Combined with anti‐PD‐L1, it boosts immune responses, offering a novel therapeutic strategy for overcoming ...
Xiang Liu   +9 more
wiley   +1 more source

Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose‐Derived Stem Cells

open access: yesAdvanced Science, EarlyView.
The impact of topography on the secretome of adipose‐derived stem cells (ADSCs) has the potential for promoting tendon regeneration. The secretome generated from ADSCs on aligned structure has a potent effect in promoting cell migration, proliferation, tenogenic differentiation, macrophage M2 polarization, and tendon mechanical function recovery ...
Qiuzi Long   +14 more
wiley   +1 more source

Gene expression analysis of cytokines and MMPs in melatonin and rhBMP-2 enhanced bone remodeling. [PDF]

open access: yesWorld J Orthop
Paulini MR   +8 more
europepmc   +1 more source

Decursin‐Loaded Nanovesicles Target Macrophages Driven by the Pathological Process of Atherosclerosis

open access: yesAdvanced Science, EarlyView.
This study presents decursin, a traditional Chinese medicine monomer, that inhibits lipid accumulation and inflammation in atherosclerosis through PKCδ interaction. A novel targeted delivery system (ALD@EM) is developed to overcome decursin's short half‐life, combining antibody‐mediated targeting, LDL‐facilitated chemotaxis, and enhanced macrophage ...
Hui Chen   +13 more
wiley   +1 more source

Vitamin D Action and Regulation of Bone Remodeling: Suppression of Osteoclastogenesis by the Mature Osteoblast

open access: bronze, 2006
Paul A. Baldock   +9 more
openalex   +1 more source

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