Results 291 to 300 of about 348,942 (354)

Citrate: a key signalling molecule and therapeutic target for bone remodeling disorder. [PDF]

Front Endocrinol (Lausanne)
Liu Q, Xue Y, Guo J, Tao L, Zhu Y.
europepmc   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Autonomic Nervous System in Bone Remodeling: From Mechanisms to Novel Therapies in Orthopedic Diseases. [PDF]

Orthop Surg
Xia R, Peng H, Zhu X, Suolang W, Pambayi STL, Yang X, Zeng Y, Shen B.   +7 more
europepmc   +1 more source

Mechanical Cues Regulate Cargo Sorting and Export at the Golgi

Advanced Science, EarlyView.
A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino, Stefania Forciniti, Edoardo Scarpa, Antonio Ranieri, Lucia Santorelli, Gabriella De Blasi, Sara Costantini, Eunjoo Jun Lee, Antonio Galeone, Alessia Calcagnì, Marinella Pirozzi, Loretta L. del Mercato, Rossella Venditti, Giovanni D'Angelo, Seetharaman Parashuraman, Tiziano Verri, Giuseppe Gigli, Elizabeth S. Sztul, Paolo Grumati, Loris Rizzello, Domenico Russo, Riccardo Rizzo   +21 more
wiley   +1 more source

Emerging regulated cell death mechanisms in bone remodeling: decoding ferroptosis, cuproptosis, disulfidptosis, and PANoptosis as therapeutic targets for skeletal disorders. [PDF]

Cell Death Discov
Hu HT, Zhang ZY, Luo Z-, Ti HB, Wu JJ, Nie H, Yuan ZD, Wu X, Zhang KY, Shi SW, Qian YQ, Wang XC, Wu JJ, Li X, Yuan FL.   +14 more
europepmc   +1 more source

Developing a Bone-Mimicking Microenvironment: Surface Coating Method for Investigating Bone Remodeling <i>in Vitro</i>. [PDF]

ACS Biomater Sci Eng
Sieberath A, Eglin D, Sprecher CM, Ferreira AM, Gentile P, Dalgarno K, Della Bella E.   +6 more
europepmc   +1 more source

sLZIP functions as a key modulator of bone remodeling by regulating the crosstalk between osteoblasts and osteoclasts. [PDF]

Exp Mol Med
Park S, Kim J, Ko J.
europepmc   +1 more source

Deletion of kinin receptor B2 enhances orthodontic tooth movement and alveolar bone remodeling. [PDF]

PLoS One
Figueiredo NC, Piacsek M, Montalvany-Antonucci CC, Santos MS, Amaral FA, Teixeira MM, Silva TA, Macari S, Pandruvada S, Andrade I.   +9 more
europepmc   +1 more source

Development of a BMU-on-a-chip model based on spatiotemporal regulation of cellular interactions in the bone remodeling cycle. [PDF]

Mater Today Bio
Woo SM, Paek K, Yoon YM, Kim H, Park SI, Kim JA.   +5 more
europepmc   +1 more source