Results 1 to 10 of about 1,847,810 (404)

Bone Resorption Assay

Bio-Protocol, 2014
The Bone resorption assay provides an easy to use protocol for quantitatively measuring in vitro osteoclast-mediated bone resorption. Osteoclasts can be seeded onto the bone slices and formation of resorption pits can be quantified via toluidinblue ...
Carina Scholtysek, Gerhard Krönke, Georg Schett   +2 more
doaj   +4 more sources

Investigation of bone resorption within a cortical basic multicellular unit using a lattice-based computational model [PDF]

Bone 50, 378-389 (2012), 2011
In this paper we develop a lattice-based computational model focused on bone resorption by osteoclasts in a single cortical basic multicellular unit (BMU). Our model takes into account the interaction of osteoclasts with the bone matrix, the interaction of osteoclasts with each other, the generation of osteoclasts from a growing blood vessel, and the ...
Anderson, Baron, Beysens, Block, Boyce, Boyde, Britz, Bronckers, Buenzli, Burger, Chambers, Civitelli, Cohen, Cooper, David W. Smith, Drasdo, Drasdo, Everts, Frost, Frost, Fukushima, García-Aznar, Gerlee, Ghaemi, Glauber, Glazier, Grynpas, Helfrich, Huang, Jaworski, Jeon, Junhwan Jeon, Manolagas, Mansury, Markus, Martin, Martin, Martin, Martin, Martin, Matsuoka, Miller, Mombach, Moshin, Nishiyama, Noble, Othmer, Othmer, Parfitt, Parfitt, Parfitt, Parfitt, Parfitt, Parfitt, Parfitt, Pascal R. Buenzli, Peruani, Peter Pivonka, Peter T. Cummings, Poplawski, Robling, Roodman, Ryser, Schienbein, Schilling, Schweitzer, Stout, Susa, Tappen, van Kampen, van Oers, van Oers, Väänänen, Walker, Zhang   +74 more
arxiv   +4 more sources

Mechanisms of Bone Resorption in Periodontitis [PDF]

Journal of Immunology Research, 2015
Alveolar bone loss is a hallmark of periodontitis progression and its prevention is a key clinical challenge in periodontal disease treatment. Bone destruction is mediated by the host immune and inflammatory response to the microbial challenge. However, the mechanisms by which the local immune response against periodontopathic bacteria disturbs the ...
Stefan A. Hienz, Sweta Paliwal, Saso Ivanovski   +2 more
openaire   +6 more sources

Governing equations of tissue modelling and remodelling: A unified generalised description of surface and bulk balance [PDF]

Buenzli PR (2016) PLoS ONE 11(4):e0152582, 2015
Several biological tissues undergo changes in their geometry and in their bulk material properties by modelling and remodelling processes. Modelling synthesises tissue in some regions and removes tissue in others. Remodelling overwrites old tissue material properties with newly formed, immature tissue properties.
Buenzli, Pascal R.
arxiv   +7 more sources

Control of bone resorption by semaphorin 4D is dependent on ovarian function. [PDF]

PLoS ONE, 2011
Osteoporosis is one of the most common bone pathologies, which are characterized by a decrease in bone mass. It is well established that bone mass, which results from a balanced bone formation and bone resorption, is regulated by many hormonal ...
Romain Dacquin, Chantal Domenget, Atsushi Kumanogoh, Hitoshi Kikutani, Pierre Jurdic, Irma Machuca-Gayet   +5 more
doaj   +6 more sources

Experimental model in vivo for quantitative assessment of bone resorption inhibition. [PDF]

, 1993
Quantitative assessment of bone resorption inhibition in vivo is not easily accomplished; methods relying on a count of osteoclasts are questionable, and histomorphometric evaluation of the bone mass presents several technical problems as well.
Cherubino P., Coci A, Di Nucci A, PAZZAGLIA, Ugo, Zatti G   +4 more
core   +3 more sources

Roles of hyaluronan in bone resorption [PDF]

BMC Musculoskeletal Disorders, 2004
Background Hyaluronan, an unsulfated glycosaminoglycan, while being closely linked to osteoclast function several years ago, has received little attention lately. Given recent new knowledge of hyaluronan's possible cell binding abilities, it is important
Prince Charles W
doaj   +4 more sources

Local mechanical stimuli regulate bone formation and resorption in mice at the tissue level. [PDF]

PLoS ONE, 2013
Bone is able to react to changing mechanical demands by adapting its internal microstructure through bone forming and resorbing cells. This process is called bone modeling and remodeling.
Friederike A Schulte, Davide Ruffoni, Floor M Lambers, David Christen, Duncan J Webster, Gisela Kuhn, Ralph Müller   +6 more
doaj   +2 more sources

Roles of Toll-like Receptor Signaling in Inflammatory Bone Resorption [PDF]

Biology
Toll-like receptors (TLRs) are pattern recognition receptors expressed in immune cells, including neutrophils, macrophages, and dendritic cells. Microbe-associated molecular patterns, including bacterial components, membranes, nucleic acids, and flagella
Tsukasa Tominari, Chiho Matsumoto, Yuki Tanaka, Kensuke Shimizu, Masaru Takatoya, Moe Sugasaki, Kento Karouji, Urara Kasuga, Chisato Miyaura, Shinji Miyata, Yoshifumi Itoh, Michiko Hirata, Masaki Inada   +12 more
doaj   +2 more sources

Autophagy Regulator Rufy 4 Promotes Osteoclastic Bone Resorption by Orchestrating Cytoskeletal Organization via Its RUN Domain [PDF]

Cells
Rufy4, a protein belonging to the RUN and FYVE domain-containing protein family, participates in various cellular processes such as autophagy and intracellular trafficking. However, its role in osteoclast-mediated bone resorption remains uncertain.
Eiko Sakai, Minoru Saito, Yu Koyanagi, Yoshitsugu Takayama, Fatima Farhana, Yu Yamaguchi, Takayuki Tsukuba   +6 more
doaj   +2 more sources