Results 91 to 100 of about 1,866,251 (380)
Nature Communications, 2020 Anti-resorptive bone therapies also inhibit bone formation, as osteoclasts secrete factors that stimulate bone formation by osteoblasts. Here, the authors identify osteoclast-secreted factors that couple bone resorption to bone formation in healthy ...
Megan M. Weivoda +19 more
doaj +1 more source
RANKL biology: bone metabolism, the immune system, and beyond
Inflammation and Regeneration, 2020 Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/macrophage–lineage cells into the bone–resorbing cells called osteoclasts.
T. Ono +3 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This study investigates the role of triply periodic minimal structures in load bearing bone tissue engineering applications. Research uses a combination of mechanical testing, material characterization, and in vitro tests to study the impact of TPMS lattice structures (gyroid, lidinoid and split‐P).
Tejas M. Koushik +2 more
wiley +1 more source
Journal of Pharmacological Sciences, 2006 .: Bone formation in adults determines the basic mass of bone and hence it is crucial to understand the mechanisms of its regulation. As remodeling is proceeding, bone resorption is determined by the physical conditions.
Masaki Noda
doaj
BoneKEy Reports, 2014 The reversal phase couples bone resorption to bone formation by generating an osteogenic environment at remodeling sites. The coupling mechanism remains poorly understood, despite the identification of a number of ‘coupling' osteogenic molecules.
J. Delaissé
semanticscholar +1 more source
Dynamics of Bone Trap-5b Level in Patients with Bone Metastases of Renal Cell Cancer at Combined Treatment [PDF]
, 2017 The objective of this study was to determine the sensitivity of tartrate-resistant acid phosphatase (Bone TRAP-5b) for early detection of bone metastases (BM) and to investigate the efficacy of bisphosphonates (BF) (zolendronic acid-ZA) in prevention of ...
Boichuk, S. (Serhiy) +3 more
core +2 more sources
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman +6 more
wiley +1 more source
RACK1 interaction with c-Src is essential for osteoclast function
Experimental and Molecular Medicine, 2019 Bone disease: scaffolding protein essential for bone resorption The interaction between RACK1, a so-called scaffolding protein that can assemble components of a signaling pathway into complexes, and c-Src, an enzyme involved in the re-organization of the
Jin Hee Park +9 more
doaj +1 more source
Histopathological evaluation of root canal filling materials for primary teeth [PDF]
, 2010 This study aimed to assess the response of apical and periapical tissues of dogs¿ teeth after root canal filling with different materials. Forty roots from dogs¿ premolars were prepared biomechanically and assigned to 4 groups filled with: Group I ...
Gatón Hernández, Patrícia +6 more
core +2 more sources
Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk
Nature Communications, 2020 Wolff’s law and the Utah Paradigm of skeletal physiology state that bone architecture adapts to mechanical loads. These models predict the existence of a mechanostat that links strain induced by mechanical forces to skeletal remodeling.
Lijun Wang +5 more
semanticscholar +1 more source