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The Mechanism Switching the Osteoclast From Short to Long Duration Bone Resorption
Frontiers in Cell and Developmental Biology, 2021 The current models of osteoclastic bone resorption focus on immobile osteoclasts sitting on the bone surface and drilling a pit into the bone matrix.
Jean-Marie Delaisse +11 more
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Osteocyte-Related Cytokines Regulate Osteoclast Formation and Bone Resorption
International Journal of Molecular Sciences, 2020 The process of bone remodeling is the result of the regulated balance between bone cell populations, namely bone-forming osteoblasts, bone-resorbing osteoclasts, and the osteocyte, the mechanosensory cell type.
H. Kitaura +9 more
semanticscholar +1 more source
Control of bone resorption by semaphorin 4D is dependent on ovarian function. [PDF]
PLoS ONE, 2011 Osteoporosis is one of the most common bone pathologies, which are characterized by a decrease in bone mass. It is well established that bone mass, which results from a balanced bone formation and bone resorption, is regulated by many hormonal ...
Romain Dacquin +5 more
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Science Translational Medicine, 2020 Independent of cathepsin K, the osteoclast-derived matrix metalloproteinases MMP9 and MMP14 codependently drive bone resorption. Codependent deconstruction Bone homeostasis encompasses a balancing act between formation of new bone and remodeling and ...
Lingxin Zhu +7 more
semanticscholar +1 more source
Definitions, 2020 Bone Resorption Stimulation involves initiation of absorption and removal of the hard connective tissue that constitutes the vertebrate skeleton and consists of a matrix of collagenous fibers impregnated chiefly with calcium phosphate and calcium ...
semanticscholar +1 more source
Malignant melanoma and bone resorption [PDF]
British Journal of Cancer, 2006 The cellular and humoral mechanisms accounting for osteolysis in skeletal metastases of malignant melanoma are uncertain. Osteoclasts, the specialised multinucleated cells that carry out bone resorption, are derived from monocyte/macrophage precursors.
Lau, Y +5 more
openaire +2 more sources
Effects of material properties of femoral hip components on bone remodeling [PDF]
, 1992 Bone loss around femoral hip stems is one of the problems threatening the long-term fixation of uncemented stems. Many believe that this phenomenon is caused by reduced stresses in the bone (stress shielding).
Grootenboer, H.J. +2 more
core +4 more sources
Inhibited Maternal Bone Resorption Suppress Fetal Rat Bone Development During Pregnancy
Frontiers in Cell and Developmental Biology, 2020 ObjectiveTo determine the relationship between maternal bone resorption and bone development in fetuses.MethodsFemale SD rats were injected with either fluorescent calcium indicator calcein alone or together with tetracycline 1 week before pregnancy ...
Huanhuan Jia +11 more
doaj +1 more source
Orthopaedic Surgery, 2021 Objective To investigate three‐dimensional distribution of bone‐resorptive lesions based on the three‐pillar classification and its effect on the disease progression of osteonecrosis of the femoral head (ONFH).
Guang‐bo Liu +10 more
doaj +1 more source
p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. [PDF]
, 2017 Bone mass is determined by the balance between bone formation, carried out by mesenchymal stem cell-derived osteoblasts, and bone resorption, carried out by monocyte-derived osteoclasts.
Ao, Junping +9 more
core +1 more source