Results 31 to 40 of about 258,684 (306)
Journal of Pharmacological Sciences, 2011 Nobiletin, a polymethoxy flavonoid, prevents cancer and inflammation, but the roles of nobiletin in bone are unclear. We examined the effects of nobiletin on bone resorption in vitro and on bone mass in ovariectomized (OVX) mice in vivo.
Suguru Harada +6 more
doaj +1 more source
ELMO1 Regulates RANKL-Stimulated Differentiation and Bone Resorption of Osteoclasts
Frontiers in Cell and Developmental Biology, 2021 Bone homeostasis is a metabolic balance between the new bone formation by osteoblasts and old bone resorption by osteoclasts. Excessive osteoclastic bone resorption results in low bone mass, which is the major cause of bone diseases such as rheumatoid ...
Xinyue Liang +7 more
doaj +1 more source
Bio-Protocol, 2014 The Bone resorption assay provides an easy to use protocol for quantitatively measuring in vitro osteoclast-mediated bone resorption. Osteoclasts can be seeded onto the bone slices and formation of resorption pits can be quantified via toluidinblue ...
Carina Scholtysek +2 more
doaj +1 more source
Focus ion beam/scanning electron microscopy characterization of osteoclastic resorption of calcium phosphate substrates [PDF]
, 2017 This article presents the application of dual focused ion beam/scanning electron microscopy (FIB-SEM) imaging for preclinical testing of calcium phosphates with osteoclast precursor cells and how this high-resolution imaging technique is able to reveal ...
Baldini, Nicola +6 more
core +2 more sources
BiomedicinesAims: This study was conducted to systematically evaluate the biomechanical impact of varying degrees of root and bone resorption resulting from periodontitis and orthodontic tooth movement (OTM) on the mandibular anterior teeth.
Jana Flatten +4 more
doaj +1 more source
Journal of Pharmacological Sciences, 2008 The vertebrate skeleton is richly innervated with adrenergic and peptidergic nerve terminals, and these play important roles in bone remodeling. Recent studies have generally shown that increased sympathetic nervous activity causes bone loss via an ...
Akifumi Togari, Michitsugu Arai
doaj +1 more source
A theory for bone resorption based on the local rupture of osteocytes cells connections: A finite element study [PDF]
, 2015 In this work, a bone damage resorption finite element model based on the disruption of the inhibitory signal transmitted between osteocytes cells in bone due to damage accumulation is developed and discussed. A strain-based stimulus function coupled to a
Abdessalem Chamekh +4 more
core +1 more source
Transient Local Bone Remodeling Effects of rhBMP-2 in an Ovine Interbody Spine Fusion Model [PDF]
, 2016 Background: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is a powerful osteoinductive morphogen capable of stimulating the migration of mesenchymal stem cells (MSCs) to the site of implantation and inducing the proliferation and ...
Badura, Jeffrey +7 more
core +1 more source
Hormone-stimulated modulation of endocytic trafficking in osteoclasts [PDF]
, 2012 Copyright @ 2012 Stenbeck, Lawrence and Albert. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and ...
Albert, AP, Lawrence, KM, Stenbeck, G
core +2 more sources
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source