Results 51 to 60 of about 258,684 (306)

Focusing on OB-OC-MΦ Axis and miR-23a to Explore the Pathogenesis and Treatment Strategy of Osteoporosis

Frontiers in Endocrinology, 2022
Osteoporosis is a bone metabolic disorder characterized by decreased bone density and deteriorated microstructure, which increases the risk of fractures.
Tian-Liang Ma, Tian-Liang Ma, Tian-Liang Ma, Peng Zhu, Zhuo-Ran Ke, Jing-Xian Chen, Yi-He Hu, Yi-He Hu, Jie Xie, Jie Xie   +9 more
doaj   +1 more source

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

A three-dimensional finite element analysis on the effects of implant materials and designs on periprosthetic tibial bone resorption.

PLoS ONE, 2021
IntroductionImplant material is a more important factor for periprosthetic tibial bone resorption than implant design after total knee arthroplasty (TKA). The virtual perturbation study was planned to perform using single case of proximal tibia model. We
Hyung Jun Park, Tae Soo Bae, Seung-Baik Kang, Hyeong Ho Baek, Moon Jong Chang, Chong Bum Chang   +5 more
doaj   +1 more source

Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists [PDF]

, 2017
Type 2 diabetes mellitus (T2DM) leads to bone fragility and predisposes to increased risk of fracture, poor bone healing and other skeletal complications.
Chantal Chenu, Guillaume Mabilleau, Iepsen, Iepsen, Marie Pereira   +4 more
core   +4 more sources

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Effect of Low-magnitude, High-frequency Vibration on Osteocytes in the Regulation of Osteoclasts [PDF]

, 2010
Osteocytes are well evidenced to be the major mechanosensor in bone, responsible for sending signals to the effector cells (osteoblasts and osteoclasts) that carry out bone formation and resorption. Consistent with this hypothesis, it has been shown that
Al-Dujaili, Saja, Guenther, Axel, Lau, Esther, Liu, Dawei, Wang, Liyun, You, Lidan   +5 more
core   +2 more sources

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Effects of fixed orthodontic lingual retainers on PDL stress, root resorption risk, and tooth displacement

Scientific Reports
To date, no study has compared the effects of CAD/CAM versus flexible multistrand wire (FMS) retainers in the presence/absence of root resorption and/or alveolar crestal bone resorption on the anterior mandibular teeth’s stresses/displacements. Therefore,
Mehrnaz Moradinejad, Marzieh Mazhari, Mohsen Mazhary, Alireza Hashemi Ashtiani, Marzie Yazdi, Vahid Rakhshan   +5 more
doaj   +1 more source

Local mechanical stimuli regulate bone formation and resorption in mice at the tissue level. [PDF]

PLoS ONE, 2013
Bone is able to react to changing mechanical demands by adapting its internal microstructure through bone forming and resorbing cells. This process is called bone modeling and remodeling.
Friederike A Schulte, Davide Ruffoni, Floor M Lambers, David Christen, Duncan J Webster, Gisela Kuhn, Ralph Müller   +6 more
doaj   +1 more source

Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro [PDF]

, 2013
Peer reviewedPublisher ...
Pappalardo, A., Thompson, K.
core   +1 more source