Results 51 to 60 of about 1,866,251 (380)

Repair of microdamage in osteonal cortical bone adjacent to bone screw.

PLoS ONE, 2014
Up to date, little is known about the repair mode of microdamage in osteonal cortical bone resulting from bone screw implantation. In this study, self-tapping titanium cortical bone screws were inserted into the tibial diaphyses of 24 adult male rabbits.
Lei Wang, Tingjun Ye, Lianfu Deng, Jin Shao, Jin Qi, Qi Zhou, Li Wei, Shijing Qiu   +7 more
doaj   +1 more source

Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity [PDF]

, 2017
Extracellular signal-regulated protein kinase 5 (ERK5) has been implicated during development and carcinogenesis. Nkx3.1-mediated Cre expression is a useful strategy to genetically manipulate the mouse prostate. While grossly normal at birth, we observed
Ahmad, Imran, Blyth, Karen, Charlesworth, Gemma, Daroszewska, Anna, Ford, Catriona, King, Ayala, Leung, Hing Y., Loveridge, Carolyn J., Mui, Ernest J., Prior, Amanda, Rose, Lorraine, Salji, Mark, Sansom, Owen, Tan, Ee Hong, van ’t Hof, Rob J., Welsh, Michelle   +15 more
core   +2 more sources

Governing equations of tissue modelling and remodelling: A unified generalised description of surface and bulk balance [PDF]

, 2016
Several biological tissues undergo changes in their geometry and in their bulk material properties by modelling and remodelling processes. Modelling synthesises tissue in some regions and removes tissue in others.
Buenzli, Pascal R.
core   +12 more sources

Tiludronate and clodronate do not affect bone structure or remodeling kinetics over a 60 day randomized trial [PDF]

, 2018
Background Tiludronate and clodronate are FDA-approved bisphosphonate drug therapies for navicular disease in horses. Although clinical studies have determined their ability to reduce lameness associated with skeletal disorders in horses, data regarding
Gillett, Ashley N., McNulty, Margaret A., Mitchell, Colin F., Richbourg, Heather A.   +3 more
core   +1 more source

Hypoxic regulation of osteoclast differentiation and bone resorption activity

Hypoxia, 2015
Bone integrity is maintained throughout life via the homeostatic actions of bone cells, namely, osteoclasts, which resorb bone, and osteoblasts, which produce bone. Disruption of this balance in favor of osteoclast activation results in pathological bone
H. Knowles
semanticscholar   +1 more source

Modulating Bone Resorption and Bone Formation in Opposite Directions in the Treatment of Postmenopausal Osteoporosis

Drugs, 2015
Bone remodeling, the fundamental process for bone renewal, is targeted by treatments of osteoporosis to correct the imbalance between bone resorption and bone formation and reduce the risk of fractures and associated clinical consequences.
N. Appelman‐Dijkstra, S. Papapoulos
semanticscholar   +1 more source

The Role of Bone and Root Resorption on the Biomechanical Behavior of Mandibular Anterior Teeth Subjected to Orthodontic Forces: A Finite Element Approach

Biomedicines
Aims: This study was conducted to systematically evaluate the biomechanical impact of varying degrees of root and bone resorption resulting from periodontitis and orthodontic tooth movement (OTM) on the mandibular anterior teeth.
Jana Flatten, Thomasz Gedrange, Christoph Bourauel, Ludger Keilig, Anna Konermann   +4 more
doaj   +1 more source

Investigation of bone resorption within a cortical basic multicellular unit using a lattice-based computational model

, 2011
In this paper we develop a lattice-based computational model focused on bone resorption by osteoclasts in a single cortical basic multicellular unit (BMU).
Anderson, Baron, Beysens, Block, Boyce, Boyde, Britz, Bronckers, Buenzli, Burger, Chambers, Civitelli, Cohen, Cooper, David W. Smith, Drasdo, Drasdo, Everts, Frost, Frost, Fukushima, García-Aznar, Gerlee, Ghaemi, Glauber, Glazier, Grynpas, Helfrich, Huang, Jaworski, Jeon, Junhwan Jeon, Manolagas, Mansury, Markus, Martin, Martin, Martin, Martin, Martin, Matsuoka, Miller, Mombach, Moshin, Nishiyama, Noble, Othmer, Othmer, Parfitt, Parfitt, Parfitt, Parfitt, Parfitt, Parfitt, Parfitt, Pascal R. Buenzli, Peruani, Peter Pivonka, Peter T. Cummings, Poplawski, Robling, Roodman, Ryser, Schienbein, Schilling, Schweitzer, Stout, Susa, Tappen, van Kampen, van Oers, van Oers, Väänänen, Walker, Zhang   +74 more
core   +2 more sources

OSTEOBLASTS MEDIATE INTERLEUKIN-1 STIMULATION OF BONE-RESORPTION BY RAT OSTEOCLASTS [PDF]

, 1986
A monocyte-derived factor with IL-1-like properties has recently been shown to cause resorption of bone in organ culture. We have investigated the action of IL-1 on disaggregated populations of osteoclasts, incubated alone or in the presence of ...
Chambers, TJ, Saklatvala, J, Thomson, BM
core   +2 more sources

Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption [PDF]

, 2019
Vav1 is a Rho/Rac guanine nucleotide exchange factor primarily expressed in hematopoietic cells. In this study, we investigated the potential role of Vav1 in osteoclast (OC) differentiation by comparing the ability of bone marrow mononuclear cells (BMMCs)
Cha, Young-Nam, Dinauer, Mary C., Jang, Jin Sun, Kang, In Soon, Kim, Chaekyun, Kim, Young-June, Lee, Zang Hee   +6 more
core   +2 more sources