Results 61 to 70 of about 1,866,251 (380)

P38 mitogen-activated protein kinase inhibitor, FR167653, inhibits parathyroid hormone related protein-induced osteoclastogenesis and bone resorption. [PDF]

PLoS ONE, 2011
p38 mitogen-activated protein kinase (MAPK) acts downstream in the signaling pathway that includes receptor activator of NF-κB (RANK), a powerful inducer of osteoclast formation and activation.
Huiren Tao, Mina Okamoto, Masataka Nishikawa, Hideki Yoshikawa, Akira Myoui   +4 more
doaj   +1 more source

Podosome organization drives osteoclast-mediated bone resorption

Cell Adhesion & Migration, 2014
Osteoclasts are the cells responsible for physiological bone resorption. A specific organization of their most prominent cytoskeletal structures, podosomes, is crucial for the degradation of mineralized bone matrix.
D. Georgess, I. Machuca‐Gayet, A. Blangy, P. Jurdic   +3 more
semanticscholar   +1 more source

Transient Local Bone Remodeling Effects of rhBMP-2 in an Ovine Interbody Spine Fusion Model [PDF]

, 2016
Background: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is a powerful osteoinductive morphogen capable of stimulating the migration of mesenchymal stem cells (MSCs) to the site of implantation and inducing the proliferation and ...
Badura, Jeffrey, Bae, Hyun W., Patel, Vikas V., Pradhan, Ben B., Sardar, Zeeshan M., Seim, Howard, Toth, Jeffrey M., Turner, Anthony S.   +7 more
core   +1 more source

Electron Microscopic Studying of Rat Bone Cells Under Microgravity Conditions [PDF]

, 2016
In the experiments on rats (SLS-2) with the use of electron microscopy there was made the study of the osteoclasts population and the peculiarities of resorptive processes in a spongy bone of the epiphyses and the iliac crest.The results of investigation
Polkovenko, O. (Olga)
core   +2 more sources

CELLULAR BIOLOGY OF BONE RESORPTION

Biological Reviews, 1993
SummaryPast knowledge and the recent developments on the formation, activation and mode of action of osteoclasts, with particular reference to the regulation of each individual step, have been reviewed. The following conclusions of consensus have emerged.1.
Mone Zaidi, Bridget E. Bax, Christopher L.-H. Huang, V.S. Shankar, David R. Blake, Clifford Robert Stevens, Michael Pazianas, A. S. M. Towhidul Alam, Baljit S. Moonga, Christopher M.R. Bax, Peter J.R. Bevis   +10 more
openaire   +4 more sources

Interleukin-10 Inhibits Bone Resorption: A Potential Therapeutic Strategy in Periodontitis and Other Bone Loss Diseases

BioMed Research International, 2014
Periodontitis and other bone loss diseases, decreasing bone volume and strength, have a significant impact on millions of people with the risk of tooth loss and bone fracture.
Qian Zhang, Bin Chen, Fuhua Yan, Jianbin Guo, Xiaofeng Zhu, Shouzhi Ma, Wenrong Yang   +6 more
semanticscholar   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Humeral bone resorption after reverse shoulder arthroplasty using uncemented stem

JSES International, 2020
Background: Humeral stem loosening has gained attention as it has been identified as a cause of revision surgery in reverse shoulder arthroplasty (RSA).
Kazuya Inoue, MD, PhD, Naoki Suenaga, MD, PhD, Naomi Oizumi, MD, PhD, Hiroshi Yamaguchi, MD, PhD, Naoki Miyoshi, MD, Noboru Taniguchi, MD, PhD, Shuzo Morita, MD, Mitsuru Munemoto, MD, PhD, Shimpei Kurata, MD, Yasuhito Tanaka, MD, PhD   +9 more
doaj  

Toddaculin, Isolated from of Toddalia asiatica (L.) Lam., Inhibited Osteoclastogenesis in RAW 264 Cells and Enhanced Osteoblastogenesis in MC3T3-E1 Cells. [PDF]

PLoS ONE, 2015
Osteoporosis with bone loss is widely recognized as a major health problem. Bone homeostasis is maintained by balancing bone formation and bone resorption.
Akio Watanabe, Momochika Kumagai, Takashi Mishima, Junya Ito, Yurika Otoki, Teppei Harada, Tsuyoshi Kato, Mikihiko Yoshida, Misora Suzuki, Izumi Yoshida, Kazuhiro Fujita, Masatoshi Watai, Kiyotaka Nakagawa, Teruo Miyazawa   +13 more
doaj   +1 more source

Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release [PDF]

, 2017
Bone cells constitutively release ATP into the extracellular environment where it acts locally via P2 receptors to regulate bone cell function. Whilst P2Y2 receptor stimulation regulates bone mineralisation, the functional effects of this receptor in ...
Arnett, T R, Gueneri, D, Hajjawai, M O, Orriss, I R, Patel, J J, Shaw, K   +5 more
core   +2 more sources