Results 61 to 70 of about 1,831,965 (356)

Tiludronate and clodronate do not affect bone structure or remodeling kinetics over a 60 day randomized trial [PDF]

, 2018
Background Tiludronate and clodronate are FDA-approved bisphosphonate drug therapies for navicular disease in horses. Although clinical studies have determined their ability to reduce lameness associated with skeletal disorders in horses, data regarding
Gillett, Ashley N., McNulty, Margaret A., Mitchell, Colin F., Richbourg, Heather A.   +3 more
core   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

A three-dimensional finite element analysis on the effects of implant materials and designs on periprosthetic tibial bone resorption.

PLoS ONE, 2021
IntroductionImplant material is a more important factor for periprosthetic tibial bone resorption than implant design after total knee arthroplasty (TKA). The virtual perturbation study was planned to perform using single case of proximal tibia model. We
Hyung Jun Park, Tae Soo Bae, Seung-Baik Kang, Hyeong Ho Baek, Moon Jong Chang, Chong Bum Chang   +5 more
doaj   +1 more source

Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity [PDF]

, 2017
Extracellular signal-regulated protein kinase 5 (ERK5) has been implicated during development and carcinogenesis. Nkx3.1-mediated Cre expression is a useful strategy to genetically manipulate the mouse prostate. While grossly normal at birth, we observed
Ahmad, Imran, Blyth, Karen, Charlesworth, Gemma, Daroszewska, Anna, Ford, Catriona, King, Ayala, Leung, Hing Y., Loveridge, Carolyn J., Mui, Ernest J., Prior, Amanda, Rose, Lorraine, Salji, Mark, Sansom, Owen, Tan, Ee Hong, van ’t Hof, Rob J., Welsh, Michelle   +15 more
core   +2 more sources

FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation

Nature Communications, 2014
Besides their cell-damaging effects in the setting of oxidative stress, reactive oxygen species (ROS) play an important role in physiological intracellular signalling by triggering proliferation and survival.
S. M. Bartell, Ha-Neui Kim, E. Ambrogini, Li Han, Srividhya Iyer, Serra Ucer, P. Rabinovitch, R. Jilka, R. Weinstein, Haibo Zhao, C. O’Brien, S. Manolagas, Maria Almeida   +12 more
semanticscholar   +1 more source

Bioresorbable and Wireless Rechargeable Implanted Na‐ion Battery for Temporary Medical Devices

Advanced Functional Materials, EarlyView.
An all‐solid‐state bioresorbable Na‐ion battery is developed, composed entirely of bio‐eliminable materials. In vivo and ex vivo tests confirmed harmless disintegration of this implanted battery. Lifetime of the implanted battery can be precisely controlled by adjusting the dissolvable encapsulation layer's thickness.
Vedi Kuyil Azhagan Muniraj, Bincy Lathakumary Vijayan, Hussien Hammoud, Roger Delattre, Marc Ramuz, Eve Djenizian, Eleonora Vandini, Daniela Giuliani, Thierry Djenizian   +8 more
wiley   +1 more source

Humeral bone resorption after reverse shoulder arthroplasty using uncemented stem

JSES International, 2020
Background: Humeral stem loosening has gained attention as it has been identified as a cause of revision surgery in reverse shoulder arthroplasty (RSA).
Kazuya Inoue, MD, PhD, Naoki Suenaga, MD, PhD, Naomi Oizumi, MD, PhD, Hiroshi Yamaguchi, MD, PhD, Naoki Miyoshi, MD, Noboru Taniguchi, MD, PhD, Shuzo Morita, MD, Mitsuru Munemoto, MD, PhD, Shimpei Kurata, MD, Yasuhito Tanaka, MD, PhD   +9 more
doaj  

Double site-bond percolation model for biomaterial implants [PDF]

, 2011
We present a double site-bond percolation model to account, on the one hand, for the vascularization and/or resorption of biomaterial implant in bones and, on the other hand, for its mechanical continuity. The transformation of the implant into osseous material, and the dynamical formation/destruction of this osseous material is accounted for by ...
arxiv   +1 more source

Foot Bone in Vivo: Its Center of Mass and Centroid of Shape [PDF]

PLoS ONE. 2011, 6(12): e28868, 2010
This paper studies foot bone geometrical shape and its mass distribution and establishes an assessment method of bone strength. Using spiral CT scanning, with an accuracy of sub-millimeter, we analyze the data of 384 pieces of foot bones in vivo and investigate the relationship between the bone's external shape and internal structure.
arxiv   +1 more source

A theory for bone resorption based on the local rupture of osteocytes cells connections: A finite element study [PDF]

, 2015
In this work, a bone damage resorption finite element model based on the disruption of the inhibitory signal transmitted between osteocytes cells in bone due to damage accumulation is developed and discussed. A strain-based stimulus function coupled to a
Abdessalem Chamekh, Hechmi Toumi, João Manuel R. S. Tavares, Khalid H. Almitani, Ridha Hambli   +4 more
core   +1 more source