Results 1 to 10 of about 380,028 (168)

Immunoporosis: Role of immune system in the pathophysiology of different types of osteoporosis

Frontiers in Endocrinology, 2022
Osteoporosis is a skeletal system disease characterized by low bone mass and altered bone microarchitecture, with an increased risk of fractures. Classical theories hold that osteoporosis is essentially a bone remodeling disorder caused by estrogen ...
Weidong Zhang, Weidong Zhang, Ruihan Gao, Ruihan Gao, Xing Rong, Xing Rong, Siqi Zhu, Siqi Zhu, Yajun Cui, Yajun Cui, Hongrui Liu, Hongrui Liu, Minqi Li, Minqi Li   +13 more
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Hydrogel scaffolds in bone regeneration: Their promising roles in angiogenesis

Frontiers in Pharmacology, 2023
Bone tissue engineering (BTE) has become a hopeful potential treatment strategy for large bone defects, including bone tumors, trauma, and extensive fractures, where the self-healing property of bone cannot repair the defect.
Jun Liu, Lili Yang, Kexin Liu, Feng Gao
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New insight of immuno-engineering in osteoimmunomodulation for bone regeneration

Regenerative Therapy, 2021
With the continuous development of bone tissue engineering, the importance of immune response in bone tissue regeneration is gradually recognized.
Long Ouyang, Jiankun Cao, Qiang Dai, Daojing Qiu   +3 more
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Exendin-4 and eldecalcitol synergistically promote osteogenic differentiation of bone marrow mesenchymal stem cells through M2 macrophages polarization via PI3K/AKT pathway

Stem Cell Research & Therapy, 2022
Background The incidence of diabetic osteoporosis is increasing. This article evaluates the effect of combination treatment with the hypoglycemic drug exendin-4 (Ex-4) and the vitamin D analog eldecalcitol (ED-71) on improving diabetic osteoporosis and ...
Yupu Lu, Shanshan Liu, Panpan Yang, Yuying Kou, Congshan Li, Hongrui Liu, Minqi Li   +6 more
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3D printing of bone tissue engineering scaffolds

Bioactive Materials, 2020
Tissue engineering is promising in realizing successful treatments of human body tissue loss that current methods cannot treat well or achieve satisfactory clinical outcomes.
Chong Wang, Wei Huang, Yu Zhou, Libing He, Zhi He, Ziling Chen, Xiao He, Shuo Tian, Jiaming Liao, Bingheng Lu, Yen Wei, Min Wang   +11 more
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Mechanical Stimulation on Mesenchymal Stem Cells and Surrounding Microenvironments in Bone Regeneration: Regulations and Applications

Frontiers in Cell and Developmental Biology, 2022
Treatment of bone defects remains a challenge in the clinic. Artificial bone grafts are the most promising alternative to autologous bone grafting. However, one of the limiting factors of artificial bone grafts is the limited means of regulating stem ...
Yuyang Sun, Ben Wan, Ben Wan, Renxian Wang, Bowen Zhang, Peng Luo, Diaodiao Wang, Jing-Jun Nie, Dafu Chen, Xinbao Wu   +9 more
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Prevention of sclerosis around cannulated screw after treatment of femoral neck fractures with bioceramic nails: a finite element analysis

BMC Musculoskeletal Disorders, 2023
Purpose Conventional cannulated screws (CS) are the main treatment method for femoral neck fractures (FNF). However, the rate of femoral head necrosis remains high after FNF treatment.
Yang Liu, Yugang Xing, Huifeng Shao, Xiaogang Wu, Yongsheng Ma, Wenming Yang, Qitai Lin, Pengcui Li, Yong He, Wangping Duan, Xiaochun Wei   +10 more
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Bioprinting for bone tissue engineering

Frontiers in Bioengineering and Biotechnology, 2022
The shape transformation characteristics of four-dimensional (4D)-printed bone structures can meet the individual bone regeneration needs, while their structure can be programmed to cross-link or reassemble by stimulating responsive materials.
Xin Kang, Xiao-Bo Zhang, Xi-Dan Gao, Ding-Jun Hao, Tao Li, Zheng-Wei Xu   +5 more
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Comparison of Individual Tissue-Engineered Bones and Allogeneic Bone in Treating Bone Defects: A Long-Term Follow-Up Study

Cell Transplantation, 2020
The treatment of bone defects has always been a challenge for orthopedic surgeons. The development of tissue engineering technology provides a novel method for repairing bone defects and has been used in animal experiments and clinical trials.
Peng Yang, Jiangling Zhou, Qiuchi Ai, Bo Yu, Moyuan Deng, Fei Luo, Zhao Xie, Junchao Xing, Tianyong Hou   +8 more
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Multi-functional osteoclasts in matrix-based tissue engineering bone

Chinese Journal of Traumatology, 2022
The repair of bone defects, especially for the large segment of bone defects, has always been an urgent problem in orthopedic clinic and attracted researchers’ attention.
Yue-Qi Chen, Wen-Hui Hu, Zi-Cai Dong, Shi-Wu Dong   +3 more
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