Results 11 to 20 of about 177,216 (256)

New insight of immuno-engineering in osteoimmunomodulation for bone regeneration

Regenerative Therapy, 2021
With the continuous development of bone tissue engineering, the importance of immune response in bone tissue regeneration is gradually recognized.
Long Ouyang, Jiankun Cao, Qiang Dai, Daojing Qiu   +3 more
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Bone Tissue Engineering and Regeneration [PDF]

BioMed Research International, 2014
Bone tissue engineering and regeneration constitutes a burgeoning new area of investigation, incorporating scientists, engineers, and clinicians with diverse academic backgrounds. With an aging global population, the need to engineer and regenerate mesenchymal tissues becomes even more pressing.
Levi, Benjamin, Péault, Bruno, James, Aaron W   +2 more
openaire   +2 more sources

Exendin-4 and eldecalcitol synergistically promote osteogenic differentiation of bone marrow mesenchymal stem cells through M2 macrophages polarization via PI3K/AKT pathway

Stem Cell Research & Therapy, 2022
Background The incidence of diabetic osteoporosis is increasing. This article evaluates the effect of combination treatment with the hypoglycemic drug exendin-4 (Ex-4) and the vitamin D analog eldecalcitol (ED-71) on improving diabetic osteoporosis and ...
Yupu Lu, Shanshan Liu, Panpan Yang, Yuying Kou, Congshan Li, Hongrui Liu, Minqi Li   +6 more
doaj   +1 more source

Prevention of sclerosis around cannulated screw after treatment of femoral neck fractures with bioceramic nails: a finite element analysis

BMC Musculoskeletal Disorders, 2023
Purpose Conventional cannulated screws (CS) are the main treatment method for femoral neck fractures (FNF). However, the rate of femoral head necrosis remains high after FNF treatment.
Yang Liu, Yugang Xing, Huifeng Shao, Xiaogang Wu, Yongsheng Ma, Wenming Yang, Qitai Lin, Pengcui Li, Yong He, Wangping Duan, Xiaochun Wei   +10 more
doaj   +1 more source

Mechanical Stimulation on Mesenchymal Stem Cells and Surrounding Microenvironments in Bone Regeneration: Regulations and Applications

Frontiers in Cell and Developmental Biology, 2022
Treatment of bone defects remains a challenge in the clinic. Artificial bone grafts are the most promising alternative to autologous bone grafting. However, one of the limiting factors of artificial bone grafts is the limited means of regulating stem ...
Yuyang Sun, Ben Wan, Ben Wan, Renxian Wang, Bowen Zhang, Peng Luo, Diaodiao Wang, Jing-Jun Nie, Dafu Chen, Xinbao Wu   +9 more
doaj   +1 more source

Comparison of Individual Tissue-Engineered Bones and Allogeneic Bone in Treating Bone Defects: A Long-Term Follow-Up Study

Cell Transplantation, 2020
The treatment of bone defects has always been a challenge for orthopedic surgeons. The development of tissue engineering technology provides a novel method for repairing bone defects and has been used in animal experiments and clinical trials.
Peng Yang, Jiangling Zhou, Qiuchi Ai, Bo Yu, Moyuan Deng, Fei Luo, Zhao Xie, Junchao Xing, Tianyong Hou   +8 more
doaj   +1 more source

Multi-functional osteoclasts in matrix-based tissue engineering bone

Chinese Journal of Traumatology, 2022
The repair of bone defects, especially for the large segment of bone defects, has always been an urgent problem in orthopedic clinic and attracted researchers’ attention.
Yue-Qi Chen, Wen-Hui Hu, Zi-Cai Dong, Shi-Wu Dong   +3 more
doaj   +1 more source

Nanoparticles for bone tissue engineering [PDF]

Biotechnology Progress, 2017
Tissue engineering (TE) envisions the creation of functional substitutes for damaged tissues through integrated solutions, where medical, biological, and engineering principles are combined. Bone regeneration is one of the areas in which designing a model that mimics all tissue properties is still a challenge.
Sílvia Vieira, Stephanie Vial, Rui L. Reis, J. Miguel Oliveira   +3 more
openaire   +5 more sources

Function and Mechanism of RGD in Bone and Cartilage Tissue Engineering

Frontiers in Bioengineering and Biotechnology, 2021
Bone and cartilage injury is common, tissue engineered scaffolds are potential means to repair. Because most of the scaffold materials used in bone and cartilage tissue engineering are bio-inert, it is necessary to increase the cellular adhesion ability ...
Meng Yang, Meng Yang, Meng Yang, Zheng-Chu Zhang, Yan Liu, Yan Liu, You-Rong Chen, You-Rong Chen, Rong-Hui Deng, Rong-Hui Deng, Zi-Ning Zhang, Zi-Ning Zhang, Jia-Kuo Yu, Jia-Kuo Yu, Jia-Kuo Yu, Fu-Zhen Yuan, Fu-Zhen Yuan   +16 more
doaj   +1 more source

Eldecalcitol effectively prevents alveolar bone loss by partially improving Th17/Treg cell balance in diabetes-associated periodontitis

Frontiers in Bioengineering and Biotechnology, 2023
Background: Diabetes-associated periodontitis (DPD) is an inflammatory and destructive disease of periodontal tissues in the diabetic population. The disease is manifested as more severe periodontal destruction and is more difficult to treat when ...
Ruihan Gao, Ruihan Gao, Weidong Zhang, Weidong Zhang, Yujun Jiang, Yujun Jiang, Junzhe Zhai, Jian Yu, Hongrui Liu, Hongrui Liu, Minqi Li, Minqi Li   +11 more
doaj   +1 more source