Towards clinical translation of upscaled osteogenic grafts using human adipose tissue progenitors [PDF]
Tissue engineering is an emerging strategy in medical field that focuses on regeneration or replacement of lost or damaged tissue and organs. Most of the tissues in human body have no or limited self renewal and regeneration potential which decrease with
Güven, Sinan
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Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham +7 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modulation of growth and differentiation of mesenchymal cells for cartilage and bone tissue engineering [PDF]
Tissue engineering is a highly promising technology for the treatment of challenging cartilage and bone lesions for which no adequate therapeutic options are available yet.
Duhr, Ralph
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Conductive Scaffolds for Bone Tissue Engineering: Current State and Future Outlook
Bone tissue engineering strategies attempt to regenerate bone tissue lost due to injury or disease. Three-dimensional (3D) scaffolds maintain structural integrity and provide support, while improving tissue regeneration through amplified cellular ...
Cheryl T. Gomillion, Damion T. Dixon
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Scaffold in bone tissue engineering [PDF]
Treatment of bone tissue injuries and diseases is still a great challenge for surgeons, but also for researchers who work with materials. Today stem cells are commonly used in bone tissue engineering.
Jokanović Vukoman +3 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Neural networks for analysis of trabecular bone in osteoarthritis [PDF]
This study investigated the correlation of age in male and female specimens with physico-mechanical properties of trabecular bone including compressive strength, bone volume fraction, structural model index, trabecular thickness factor, level of inter ...
Khovanova, N. A. +2 more
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Novel bone graft substitutes in bone tissue engineering [PDF]
Objective(s): Globally, the prevalence of bone illnesses and diseases has been significantly rising. Bone tissue engineering (BTE), which can be produced continuously and doesn’t transmit disease, has been suggested as a possible alternative to the ...
Seyedeh Mona Haghi +5 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source

