Results 41 to 50 of about 382,251 (299)

Prospects of micromass culture technology in tissue engineering [PDF]

, 2007
Tissue engineering of bone and cartilage tissue for subsequent implantation is of growing interest in cranio- and maxillofacial surgery. Commonly it is performed by using cells coaxed with scaffolds. Recently, there is a controversy concerning the use of
Jörg GK Handschel, Rita A Depprich, Norbert R Kübler, Hans-Peter Wiesmann, Michelle Ommerborn, Ulrich Meyer   +5 more
core   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Tissue engineered bone as an alternative for repairing bone defects

Dental Journal, 2010
Background: Dentist especially oral surgeon, are frequently faced with defect in bone resulting from disease or trauma. If the defect is small, it will frequently has a good healing, however, if the defect is larger, incomplete regeneration often occurs ...
Evy Eida Vitria, Benny S. Latif
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Novel bone graft substitutes in bone tissue engineering [PDF]

Nanomedicine Journal
Objective(s): Globally, the prevalence of bone illnesses and diseases has been significantly rising. Bone tissue engineering (BTE), which can be produced continuously and doesn’t transmit disease, has been suggested as a possible alternative to the ...
Seyedeh Mona Haghi, Mona Gharavian, Emad Azimi, Kiarash Nazari Tavalaei, Shirin Hamed Akbari Toosi, Marzieh Mohammadi   +5 more
doaj   +1 more source

Types of scaffolds and their application in bone tissue engineering [PDF]

, 2015
Bone tissue engineering is founded on the conception of bone structure, bone mechanics and tissue creature as it aims to restore, maintain, or improve tissue functions that are defective or have been lost by different pathological conditions.
Bosnakovski, Darko, Volceva, Milena
core  

3D Printed TCP-Based Scaffold Incorporating VEGF-Loaded PLGA Microspheres for Craniofacial Tissue Engineering [PDF]

, 2017
Objective Vascularization is a critical process during bone regeneration/repair and the lack of tissue vascularization is recognized as a major challenge in applying bone tissue engineeringmethods for cranial and maxillofacial surgeries.
D. Lobner, E. Dashtimoghadam, F. Bastami, F. Fahimipour, K. Khoshroo, L. Tayebi, M. Rasoulianboroujeni, M. Tahriri   +7 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Carbon based nanomaterials for tissue engineering of bone: Building new bone on small black scaffolds: A review

Journal of Advanced Research, 2019
Tissue engineering is a rapidly-growing approach to replace and repair damaged and defective tissues in the human body. Every year, a large number of people require bone replacements for skeletal defects caused by accident or disease that cannot heal on ...
Reza Eivazzadeh-Keihan, Ali Maleki, Miguel de la Guardia, Milad Salimi Bani, Karim Khanmohammadi Chenab, Paria Pashazadeh-Panahi, Behzad Baradaran, Ahad Mokhtarzadeh, Michael R. Hamblin   +8 more
doaj   +1 more source

Magnetic Nanoparticles in Bone Tissue Engineering

Nanomaterials, 2022
Large bone defects with limited intrinsic regenerative potential represent a major surgical challenge and are associated with a high socio-economic burden and severe reduction in the quality of life. Tissue engineering approaches offer the possibility to
Akshith Dasari, Jingyi Xue, Sanjukta Deb
doaj   +1 more source