Results 41 to 50 of about 199,444 (302)

Current Trends in Bone Tissue Engineering [PDF]

BioMed Research International, 2014
The development of tissue engineering and regeneration constitutes a new platform for translational medical research. Effective therapies for bone engineering typically employ the coordinated manipulation of cells, biologically active signaling molecules, and biomimetic, biodegradable scaffolds. Bone tissue engineering has become increasingly dependent
Marco Mravic, Bruno Péault, Aaron W. James   +2 more
openaire   +3 more sources

Towards clinical translation of upscaled osteogenic grafts using human adipose tissue progenitors [PDF]

, 2012
Tissue engineering is an emerging strategy in medical field that focuses on regeneration or replacement of lost or damaged tissue and organs. Most of the tissues in human body have no or limited self renewal and regeneration potential which decrease with
Güven, Sinan
core   +1 more source

The effect of polystyrene sodium sulfonate grafting on polyethylene terephthalate artificial ligaments on in vitro mineralisation and in vivo bone tissue integration [PDF]

, 2013
This study investigates the impact of polystyrene sodium sulfonate (PolyNaSS) grafting onto the osseointegration of a polyethylene terephthalate artificial ligament (Ligament Advanced Reinforcement System, LARS ) used for Anterior Cruciate Ligament (ACL).
VIATEAU, Véronique, GUÉRARD, Sandra, CASTNER, David G., Manaserro, Mathieu, Castner, David, MANASSERO, Mathieu, VAQUETTE, Cédryck, ANAGNOSTOU, Fani, MIGONNEY, Véronique   +8 more
core   +1 more source

Scaffold in bone tissue engineering [PDF]

Stomatološki glasnik Srbije, 2017
Treatment of bone tissue injuries and diseases is still a great challenge for surgeons, but also for researchers who work with materials. Today stem cells are commonly used in bone tissue engineering.
Jokanović Vukoman, Čolović Božana, Popović-Bajić Marijana, Živković-Sandić Marija   +3 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tissue engineered bone as an alternative for repairing bone defects

Dental Journal, 2010
Background: Dentist especially oral surgeon, are frequently faced with defect in bone resulting from disease or trauma. If the defect is small, it will frequently has a good healing, however, if the defect is larger, incomplete regeneration often occurs ...
Evy Eida Vitria, Benny S. Latif
doaj   +1 more source

Application of decellularized bone matrix as a bioscaffold in bone tissue engineering

Journal of Biological Engineering, 2022
Autologous bone grafts are commonly used as the gold standard to repair and regenerate diseased bones. However, they are strongly associated with postoperative complications, especially at the donor site, and increased surgical costs.
Halimeh Amirazad, Mehdi Dadashpour, Nosratollah Zarghami   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Novel bone graft substitutes in bone tissue engineering [PDF]

Nanomedicine Journal
Objective(s): Globally, the prevalence of bone illnesses and diseases has been significantly rising. Bone tissue engineering (BTE), which can be produced continuously and doesn’t transmit disease, has been suggested as a possible alternative to the ...
Seyedeh Mona Haghi, Mona Gharavian, Emad Azimi, Kiarash Nazari Tavalaei, Shirin Hamed Akbari Toosi, Marzieh Mohammadi   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source