Results 101 to 110 of about 2,993,509 (396)

A synthetic three-dimensional niche system facilitates generation of functional hematopoietic cells from human-induced pluripotent stem cells

Journal of Hematology & Oncology, 2016
Background The efficient generation of hematopoietic stem cells (HSCs) from human-induced pluripotent stem cells (iPSCs) holds great promise in personalized transplantation therapies.
Yulin Xu, Wei Shan, Xia Li, Binsheng Wang, Senquan Liu, Yebo Wang, Yan Long, Ruxiu Tie, Limengmeng Wang, Shuyang Cai, Hao Zhang, Yu Lin, Mingming Zhang, Weiyan Zheng, Yi Luo, Xiaohong Yu, Jiing-Kuan Yee, Junfeng Ji, He Huang   +18 more
doaj   +1 more source

3D‐Printed Multidimensional Bionic Mg‐MC/PLGA Composite for Tailored Repair of Segmental Long Bone Defects

Advanced Healthcare Materials, EarlyView.
This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu, Shuai Zhou, Tingting Zou, Guangzhao Hou, Qian Xiao, Lin Li, Jianjun Yang, Wei Chen, Yingze Zhang, Hongzhi Lv   +9 more
wiley   +1 more source

Clinical Reference Strategy for the Selection of Treatment Materials for Maxillofacial Bone Transplantation: A Systematic Review and Network Meta-Analysis. [PDF]

Tissue Eng Regen Med, 2022
Zhang S, Zhang X, Li Y, Mao X, Liu R, Qi Y, Lee ES, Jiang HB.   +7 more
europepmc   +1 more source

Quality of Life and psychopathology in adults who underwent Hematopoietic Stem Cell Transplantation (HSCT) in childhood: a qualitative and quantitative analysis. [PDF]

, 2017
Background: Patients who undergo pediatric Hematopoietic Stem Cell Transplantation (HSCT) may experience long-term psychological sequelae and poor Quality of Life (QoL) in adulthood. This study aimed to investigate subjective illness experience, QoL, and
Basso, G., Boscolo, Valentina, Calore, E., Cattelan, C., Di Florio, N., Mainardi, C., Marzollo, A., Messina, C., Pillon, M., Porreca, A., Sinatora, F., Traverso, A., Tremolada, M., Zanato, S.   +13 more
core   +2 more sources

Practical Guide to the Design of Granular Hydrogels for Customizing Complex Cellular Microenvironments

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley   +1 more source

Decitabine plus CLAG chemotherapy as a bridge to haploidentical transplantation in the setting of acute myeloid leukemia relapse after HLA-matched sibling transplantation: a case report

BMC Cancer, 2019
Background Patients with relapsed/refractory acute myeloid leukemia after hematopoietic stem cell transplantation (HSCT) have a poor prognosis, with a 2-year survival rate of 14%. The optimal treatment for these patients remains unclear.
Mengqi Jin, Yongxian Hu, Wenjun Wu, Yi Luo, Yamin Tan, Jian Yu, Aiyun Jin, Luxin Yang, He Huang, Guoqing Wei   +9 more
doaj   +1 more source

3D Customized Biological Tibial Intramedullary Nail Fixation for the Treatment of Fracture after Massive Allograft Bone Transplantation of Tibial Osteosarcoma: A Case Report. [PDF]

Orthop Surg, 2022
Yang H, Fang X, Xiong Y, Duan H, Zhang W.   +4 more
europepmc   +1 more source

Bone Marrow Transplantation Conference [PDF]

, 1959
S. Warren, W Dameshek
openalex   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair

Journal of Experimental & Clinical Cancer Research, 2018
Background With the development of novel therapeutic agents, the survival of multiple myeloma (MM) patients has much improved. However, the disease is incurable due to drug resistance. Previous studies have found that high-mobility group box 1 (HMGB1) is
Xing Guo, Donghua He, Enfan Zhang, Jing Chen, Qingxiao Chen, Yi Li, Li Yang, Yang Yang, Yi Zhao, Gang Wang, Jingsong He, Zhen Cai   +11 more
doaj   +1 more source