Results 31 to 40 of about 156,386 (240)

Endogenous PTH deficiency impairs fracture healing and impedes the fracture-healing efficacy of exogenous PTH(1-34). [PDF]

open access: yesPLoS ONE, 2011
Although the capacity of exogenous PTH1-34 to enhance the rate of bone repair is well established in animal models, our understanding of the mechanism(s) whereby PTH induces an anabolic response during skeletal repair remains limited.
Yongxin Ren   +7 more
doaj   +1 more source

New technologies in rhinoplasty : a comprehensive workflow for computer-assisted planning and execution [PDF]

open access: yes, 2019
Rhinoplasty in facial cleft patients is among the most challenging types of reconstructive facial surgery due to its variability Advances in 3-dimensional imaging enable improved preoperative assessment in rhinoplasty.
Codazzi   +7 more
core   +1 more source

Elastomeric Osteoconductive Synthetic Scaffolds with Acquired Osteoinductivity Expedite the Repair of Critical Femoral Defects in Rats [PDF]

open access: yes, 2010
Regenerative medicine aspires to reduce reliance on or overcome limitations associated with donor tissue-mediated repair. Structural bone allografts are commonly used in orthopedic surgery, with a high percentage of graft failure due to poor tissue ...
April Mason-Savas   +7 more
core   +2 more sources

Unbiased gene expression analysis of the delayed fracture healing observed in Zucker diabetic fatty rats

open access: yesBone & Joint Research, 2023
Aims: Impaired fracture repair in patients with type 2 diabetes mellitus (T2DM) is not fully understood. In this study, we aimed to characterize the local changes in gene expression (GE) associated with diabetic fracture. We used an unbiased approach to
Jonghoo Sung   +7 more
doaj   +1 more source

Loss of Bcl-3 delays bone fracture healing through activating NF-κB signaling in mesenchymal stem cells

open access: yesJournal of Orthopaedic Translation, 2022
Background: Bone fracture healing is a postnatal regenerative process in which fibrocartilaginous callus formation and bony callus formation are important. Bony callus formation requires osteoblastic differentiation of MSCs.
Fuxiao Wang   +9 more
doaj  

The influence of M-CSF on fracture healing in a mouse model

open access: yesScientific Reports, 2021
Macrophage colony-stimulating factor 1 (M-CSF) is known to play a critical role during fracture repair e.g. by recruiting stem cells to the fracture site and impacting hard callus formation by stimulating osteoclastogenesis.
Julia Starlinger   +5 more
doaj   +1 more source

Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway [PDF]

open access: yes, 2020
We previously established that DNA methyltransferase 3b (Dnmt3b) is the sole Dnmt responsive to fracture repair and that Dnmt3b expression is induced in progenitor cells during fracture repair.
Abu-Amer, Yousef   +8 more
core   +1 more source

Extracorporeal Shock Wave Treatment for Defective Nonunion of the Radius: A Rabbit Model

open access: yesJournal of Orthopaedic Surgery, 2006
Purpose. To investigate the effect of extracorporeal shock wave treatment (ESWT) on bony union using volume analysis of the callus mass by computed tomography and histology. Methods.
O Bulut   +5 more
doaj   +1 more source

Validation of the modified radiographic union score for tibia fractures (mRUST) in murine femoral fractures

open access: yesFrontiers in Endocrinology, 2022
Bony union is a primary predictor of outcome after surgical fixation of long bone fractures. Murine models offer many advantages in assessing bony healing due to their low costs and small size.
Vincent J. Alentado   +15 more
doaj   +1 more source

Traumatic temporomandibular joint bony ankylosis in growing rats

open access: yesBMC Oral Health, 2022
Background The pathogenesis of traumatic temporomandibular joint (TMJ) bony ankylosis remains unknown. This study aimed to explore the pathogenesis of traumatic TMJ bony ankylosis in a rat model.
Zhen Ma   +10 more
doaj   +1 more source

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