Results 31 to 40 of about 157,567 (254)
Background To estimate the effects of different intensities of intermittent pneumatic soft-tissue compression on bone defect repair in an animal model. Methods Five mm radial bone defect in length was made in 64 mature New Zealand rabbits and all animals
Weilong Diwu+6 more
doaj +1 more source
NOTCH signaling in skeletal progenitors is critical for fracture repair [PDF]
Fracture nonunions develop in 10%–20% of patients with fractures, resulting in prolonged disability. Current data suggest that bone union during fracture repair is achieved via proliferation and differentiation of skeletal progenitors within periosteal ...
Awad, Hani A+8 more
core +2 more sources
Endogenous PTH deficiency impairs fracture healing and impedes the fracture-healing efficacy of exogenous PTH(1-34). [PDF]
Although the capacity of exogenous PTH1-34 to enhance the rate of bone repair is well established in animal models, our understanding of the mechanism(s) whereby PTH induces an anabolic response during skeletal repair remains limited.
Yongxin Ren+7 more
doaj +1 more source
Aims: Impaired fracture repair in patients with type 2 diabetes mellitus (T2DM) is not fully understood. In this study, we aimed to characterize the local changes in gene expression (GE) associated with diabetic fracture. We used an unbiased approach to
Jonghoo Sung+7 more
doaj +1 more source
Cone beam CT of the musculoskeletal system : clinical applications [PDF]
Objectives: The aim of this pictorial review is to illustrate the use of CBCT in a broad spectrum of musculoskeletal disorders and to compare its diagnostic merit with other imaging modalities, such as conventional radiography (CR), Multidetector ...
Desimpel, Julie+2 more
core +2 more sources
Callus formation in bone fractures combined with brain injury in rat
Objective: The objective of this study was to determine the speed of bony union and the serum levels of biomarkers in the setting of bone fractures combined with brain injury.
Yu-Ping Chen, Hsin-Chin Shih
doaj +1 more source
Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway [PDF]
We previously established that DNA methyltransferase 3b (Dnmt3b) is the sole Dnmt responsive to fracture repair and that Dnmt3b expression is induced in progenitor cells during fracture repair.
Abu-Amer, Yousef+8 more
core +1 more source
Elastomeric Osteoconductive Synthetic Scaffolds with Acquired Osteoinductivity Expedite the Repair of Critical Femoral Defects in Rats [PDF]
Regenerative medicine aspires to reduce reliance on or overcome limitations associated with donor tissue-mediated repair. Structural bone allografts are commonly used in orthopedic surgery, with a high percentage of graft failure due to poor tissue ...
April Mason-Savas+7 more
core +2 more sources
Extracorporeal Shock Wave Treatment for Defective Nonunion of the Radius: A Rabbit Model
Purpose. To investigate the effect of extracorporeal shock wave treatment (ESWT) on bony union using volume analysis of the callus mass by computed tomography and histology. Methods.
O Bulut+5 more
doaj +1 more source
The influence of M-CSF on fracture healing in a mouse model
Macrophage colony-stimulating factor 1 (M-CSF) is known to play a critical role during fracture repair e.g. by recruiting stem cells to the fracture site and impacting hard callus formation by stimulating osteoclastogenesis.
Julia Starlinger+5 more
doaj +1 more source