Results 41 to 50 of about 7,066 (201)

Inhibition of Midkine Augments Osteoporotic Fracture Healing. [PDF]

open access: yesPLoS ONE, 2016
The heparin-binding growth and differentiation factor midkine (Mdk) is proposed to negatively regulate osteoblast activity and bone formation in the adult skeleton.
Melanie Haffner-Luntzer   +9 more
doaj   +1 more source

Soft-tissue Driven Craniomaxillofacial Surgical Planning [PDF]

open access: yesarXiv, 2023
In CMF surgery, the planning of bony movement to achieve a desired facial outcome is a challenging task. Current bone driven approaches focus on normalizing the bone with the expectation that the facial appearance will be corrected accordingly. However, due to the complex non-linear relationship between bony structure and facial soft-tissue, such bone ...
arxiv  

Fully automated segmentation of callus by micro-CT compared to biomechanics

open access: yesJournal of Orthopaedic Surgery and Research, 2017
Background A high percentage of closed femur fractures have slight comminution. Using micro-CT (μCT), multiple fragment segmentation is much more difficult than segmentation of unfractured or osteotomied bone.
Oliver Bissinger   +5 more
doaj   +1 more source

Increased Osteoblast GαS Promotes Ossification by Suppressing Cartilage and Enhancing Callus Mineralization During Fracture Repair in Mice

open access: yesJBMR Plus, 2023
GαS, the stimulatory G protein α‐subunit that raises intracellular cAMP levels by activating adenylyl cyclase, plays a vital role in bone development, maintenance, and remodeling. Previously, using transgenic mice overexpressing GαS in osteoblasts (GS‐Tg)
Kathy K Lee   +3 more
doaj   +1 more source

The interplay between tissue healing and bone remodeling around immediately loaded tooth replacement implants [PDF]

open access: yes, 2019
Long-term bone healing/adaptation after a dental implant treatment starts with diffusion of mesenchymal stem cells to the fracture callus and their subsequent differentiation. The healing phase is followed by the bone-remodeling phase. In this work, a mechano-regulatory cellular differentiation model was used to simulate tissue healing around an ...
arxiv   +1 more source

Dynamic Micromechanical Characterization of 3D Printed Bone In Vitro Models Manufactured via Vat Photopolymerization

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a novel approach to designing and fabricating high‐porosity 3D‐printed scaffolds using a customized resin. Scaffold geometry, cellular interactions, and mechanical properties are analyzed to demonstrate these engineered bone models.
Sera Choi   +6 more
wiley   +1 more source

Systemic treatment with telmisartan improves femur fracture healing in mice. [PDF]

open access: yesPLoS ONE, 2014
Recent clinical studies indicated that angiotensin receptor blockers (ARBs) would decrease the risk of bone fractures in the elderly populations. There is little known about the role of the ARBs in the process of fracture healing.
Xiong Zhao   +8 more
doaj   +1 more source

Outcome of Early Weight Bearing Cast for the Treatment of Jones Fracture

open access: yesJournal of Bahria University Medical and Dental College, 2023
Objective: To determine the radiological and functional outcome of acute Jones fracture treated conservatively in early weight bearing cast. Study Design and Setting: This study was conducted in Orthopaedic Division Lady Reading Hospital Peshawar.
Faaiz Ali Shah   +3 more
doaj   +1 more source

Real diffusion with complex spectral gap [PDF]

open access: yesarXiv, 2023
The low-lying eigenvalues of the generator of a Langevin process are known to satisfy the Eyring-Kramers law in the low temperature regime under suitable assumptions. These eigenvalues are generically real. We construct generators whose spectral gap is given by non-real eigenvalues or by a real eigenvalue having a Jordan block.
arxiv  

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

open access: yesAdvanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan   +4 more
wiley   +1 more source

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