Bordetella parapertussis isolates not expressing pertactin circulating in France [PDF]
Surprisingly, most Bordetella parapertussis isolates collected in France since 2007 do not express pertactin, owing to mutations in the structural gene encoding this protein. We used a 454 pyrosequencing strategy to study and compare the genetics of two B.
Bouchez, Valérie +4 more
openaire +2 more sources
Construction of Minitransposons for Constitutive and Inducible Expression of Pertussis Toxin in Bvg-Negative Bordetella-Bronchiseptica [PDF]
Appropriately detoxified pertussis toxin (PT) of Bordetella pertussis is considered to be an essential component of new-generation whooping cough vaccines, but the development of a procedure to obtain high levels of purified toxin has been and continues ...
Rohde, Manfred +3 more
core
ABSTRACT Background We evaluated the effectiveness of the influenza vaccine programme against infection among emergency hospital admissions with respiratory conditions in Northern Ireland during the 2023/2024 influenza season. Methods Using a test‐negative design, we compared the odds of vaccination between patients who tested positive (cases) and ...
Magda Bucholc +2 more
wiley +1 more source
A recombinant iron transport protein from Bordetella pertussis confers protection against Bordetella parapertussis [PDF]
ABSTRACTWhooping cough, which is caused by Bordetella pertussis and B. parapertussis, is a reemerging disease. New protective antigens are needed to improve the efficacy of current vaccines against both species. Using proteomic tools, it was here found that B.
Álvarez Hayes, Jimena +8 more
openaire +4 more sources
Flagellin typing of Bordetella bronchiseptica strains originating from different host species [PDF]
Bordetella bronchiseptica is a widespread Gram-negative pathogen occurring in different mammal species. It is known to play a role in the aetiology of infectious atrophic rhinitis of swine, canine kennel cough, respiratory syndromes of cats, rabbits and ...
Khayer, Bernadett +2 more
core +1 more source
Abstract The use of polyhydroxybutyrate (PHB) bioplastics has the potential to create a circular and sustainable recycling plastic system. Here, we focus on PHB degradation and characterize the multidomain PHB hydrolyzing enzyme from the extremophile Thermanaeromonas tohohensis.
Stephen Quirk +5 more
wiley +1 more source
On the origin and evolution of biosynthetic pathways: integrating microarray data with structure and organization of the Common Pathway genes [PDF]
Background: The lysine, threonine, and methionine biosynthetic pathways share the three initial enzymatic steps, which are referred to as the Common Pathway (CP). In Escherichia coli three different aspartokinases (AKI, AKII, AKIII, the products of thrA,
Marco Fondi, Matteo Brilli, Renato Fani
core +3 more sources
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) in solid organ transplant recipients has been reported in adults. However, data on children are scarce. We report a case of an allogeneic HSCT in a 14‐year‐old girl to treat idiopathic very severe aplastic anemia (SAA). Case Presentation The girl developed end‐stage renal disease at the
Gintarė Mierkienė +4 more
wiley +1 more source
Polymorphism of Repeated Regions of Pertactin in Bordetella pertussis , Bordetella parapertussis , and Bordetella bronchiseptica [PDF]
ABSTRACT Pertactin is an outer membrane protein expressed by Bordetella pertussis , Bordetella parapertussis , and Bordetella bronchiseptica that induces protective immunity to Bordetella infections.
C, Boursaux-Eude, N, Guiso
openaire +3 more sources
Within-host dynamics of infection: from ecological insights to evolutionary predictions. [PDF]
O.R. is supported by a University Research Fellowship from The Royal Society.This is the final version of the article.
Graham, Andrea L, Restif, Olivier
core +2 more sources

