Results 71 to 80 of about 3,188 (191)
Rebound of Respiratory Virus Activity and Seasonality to Pre‐Pandemic Patterns
ABSTRACT The emergence of SARS‐CoV‐2 and the implementation of non‐pharmaceutical interventions (NPIs) profoundly disrupted the transmission dynamics of respiratory viruses, altering their epidemiology and seasonality. However, comprehensive long‐term data on these shifts and their post‐pandemic implications remain limited.
Rainer Gosert +18 more
wiley +1 more source
Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes [PDF]
Pertussis toxin, the major virulence factor of Bordetella pertussis, is not produced by the closely related species Bordetella parapertussis and Bordetella bronchiseptica. It is shown here that these two species possess but do not express the complete toxin operon.
B, Aricò, R, Rappuoli
openaire +2 more sources
Comparison of Bordetella species identification among differing rt-PCR assays in the United States
In the United States, the general laboratory method for diagnosing pertussis, caused by Bordetella pertussis, is real-time PCR (rt-PCR) targeting insertion sequence 481 (IS481).
Matthew Cole +7 more
doaj +1 more source
Saliva and Anterior Nasal Samples for Detecting Respiratory Viruses in Children
ABSTRACT For detecting respiratory viruses, a nasopharyngeal swab sample for polymerase chain reaction (PCR) assays has been the benchmark. Less discomfort related to sampling is requested especially for children, and thus other sample types have been suggested.
Anu Haaramo +5 more
wiley +1 more source
ABSTRACT Background Human metapneumovirus (hMPV) has been increasingly recognized as a major contributor to respiratory infections in all age groups. Owing to its recent discovery, available data on the burden of hMPV in adults are still scant and heterogeneous.
Alexander Domnich +6 more
wiley +1 more source
A recently developed shared-primer polymerase chain reaction (PCR) was investigated, in an ongoing pertussis surveillance study for discrimination of Bordetella parapertussis and Bordetella pertussis organisms, by using specific biotin-labelled ...
Cloot, O. +7 more
core +1 more source
In vitro susceptibility of Bordetella parapertussis to various antimicrobial agents [PDF]
The in vitro activity of 18 antimicrobial agents against 32 strains of Bordetella parapertussis isolated from whooping cough patients was studied. The most active antimicrobial agents were piperacillin and minocycline, followed (in descending order of activity) by moxalactam, erythromycin, cefoperazone, tetracycline, ampicillin, cefotaxime ...
M, Watanabe, Y, Haraguchi
openaire +2 more sources
ABSTRACT Outer membrane vesicles (OMVs) are nanosized vesicles naturally secreted by Gram‐negative bacteria and represent a promising platform for vaccine development. OMVs possess inherent immunostimulatory properties due to the presence of pathogen‐associated molecular patterns (PAMPs), providing self‐adjuvanting capabilities and the ability to ...
Asja Garling +4 more
wiley +1 more source
In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to six new oral cephalosporins [PDF]
Of six new oral cephalosporins, cefixime and cefpodoxime were the most active (MIC for 90% of isolates tested [MIC90], 16 micrograms/ml) against Bordetella pertussis, followed by cefetamet, cefprozil, and loracarbef (LY163892) (MIC90, 64 micrograms/ml) and ceftibuten (MIC90, 128 micrograms/ml).
J E, Hoppe, J, Müller
openaire +2 more sources
ABSTRACT Background We evaluated the effectiveness of the influenza vaccine programme against infection among emergency hospital admissions with respiratory conditions in Northern Ireland during the 2023/2024 influenza season. Methods Using a test‐negative design, we compared the odds of vaccination between patients who tested positive (cases) and ...
Magda Bucholc +2 more
wiley +1 more source

