Results 91 to 100 of about 4,734 (199)

Construction of Minitransposons for Constitutive and Inducible Expression of Pertussis Toxin in Bvg-Negative Bordetella-Bronchiseptica [PDF]

, 1991
Appropriately detoxified pertussis toxin (PT) of Bordetella pertussis is considered to be an essential component of new-generation whooping cough vaccines, but the development of a procedure to obtain high levels of purified toxin has been and continues ...
Rohde, Manfred, Timmis, Kenneth N., Walker, Mark J., Wehland, Jurgen   +3 more
core  

A Newly Discovered Bordetella Species Carries a Transcriptionally Active CRISPR-Cas with a Small Cas9 Endonuclease [PDF]

, 2015
Background Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (cas) are widely distributed among bacteria.
Dudley, Edward G., Harvill, Eric T., Hu, Kai, Ivanov, Yury V., Linz, Bodo, Register, Karen B., Rivera, Israel, Shariat, Nikki   +7 more
core   +2 more sources

Influenza Vaccine Effectiveness During the 2023/2024 Season: A Test‐Negative Case–Control Study Among Emergency Hospital Admissions With Respiratory Conditions in Northern Ireland

Influenza and Other Respiratory Viruses, Volume 19, Issue 9, September 2025.
ABSTRACT Background We evaluated the effectiveness of the influenza vaccine programme against infection among emergency hospital admissions with respiratory conditions in Northern Ireland during the 2023/2024 influenza season. Methods Using a test‐negative design, we compared the odds of vaccination between patients who tested positive (cases) and ...
Magda Bucholc, Mark G. O'Doherty, Declan T. Bradley   +2 more
wiley   +1 more source

A recombinant iron transport protein from Bordetella pertussis confers protection against Bordetella parapertussis [PDF]

Microbiology and Immunology, 2017
ABSTRACTWhooping cough, which is caused by Bordetella pertussis and B. parapertussis, is a reemerging disease. New protective antigens are needed to improve the efficacy of current vaccines against both species. Using proteomic tools, it was here found that B.
Álvarez Hayes, Jimena, Oviedo, Juan Marcos, Valdez, Hugo Alberto, Laborde, Juan Martín, Maschi, Fabricio Alejandro, Ayala, Miguel Ángel, Shah, Rohan, Fernandez Lahore, Marcelo, Rodríguez, María Eugenia   +8 more
openaire   +4 more sources

A multidomain hydrolase from the thermophile Thermanaeromonas toyohensis degrades high molecular mass forms of polyhydroxybutyrate

Protein Science, Volume 34, Issue 8, August 2025.
Abstract The use of polyhydroxybutyrate (PHB) bioplastics has the potential to create a circular and sustainable recycling plastic system. Here, we focus on PHB degradation and characterize the multidomain PHB hydrolyzing enzyme from the extremophile Thermanaeromonas tohohensis.
Stephen Quirk, Gwendell M. Thomas, Lily J. Wallace, Megan J. Woody, Mary E. Peek, Raquel L. Lieberman   +5 more
wiley   +1 more source

Case Report: Hematopoietic Stem Cell Transplantation to Treat Severe Acquired Aplastic Anemia in a Pediatric Kidney Transplant Recipient

Pediatric Transplantation, Volume 29, Issue 5, August 2025.
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) in solid organ transplant recipients has been reported in adults. However, data on children are scarce. We report a case of an allogeneic HSCT in a 14‐year‐old girl to treat idiopathic very severe aplastic anemia (SAA). Case Presentation The girl developed end‐stage renal disease at the
Gintarė Mierkienė, Goda Elizabeta Vaitkevičienė, Karolis Ažukaitis, Augustina Jankauskienė, Jelena Rascon   +4 more
wiley   +1 more source

Polymorphism of Repeated Regions of Pertactin in Bordetella pertussis , Bordetella parapertussis , and Bordetella bronchiseptica [PDF]

Infection and Immunity, 2000
ABSTRACT Pertactin is an outer membrane protein expressed by Bordetella pertussis , Bordetella parapertussis , and Bordetella bronchiseptica that induces protective immunity to Bordetella infections.
C, Boursaux-Eude, N, Guiso
openaire   +3 more sources

Determination of Serum Antibody to Bordetella pertussis Adenylate Cyclase Toxin in Vaccinated and Unvaccinated Children and in Children and Adults with Pertussis [PDF]

, 2017
Presence of antibody to adenylate cyclase toxin (ACT) has been noted following Bordetella pertussis infection. Because ACT is not presently in any acellular pertussis vaccines, it has been considered as a possible antigen to use in B.
Cherry, James D., Corbel, Michael J., Heininger, Ulrich, Newland, Penny, Patel, Kashmira, Xing, Dorothy X. L.   +5 more
core  

Rates of transposition in Escherichia coli [PDF]

, 2013
The evolutionary role of transposable elements (TEs) is still highly controversial. Two key parameters, the transposition rate (u and w, for replicative and non-replicative transposition) and the excision rate (e) are fundamental to understanding their ...
Bourgard, C., Gordo, I., Sousa, A., Wahl, L. M.   +3 more
core   +1 more source

Bordetella pertussis, the Causative Agent of Whooping Cough, Evolved from a Distinct, Human-Associated Lineage of B. bronchiseptica.

PLoS Pathogens, 2005
Bordetella pertussis, B. bronchiseptica, B. parapertussis(hu), and B. parapertussis(ov) are closely related respiratory pathogens that infect mammalian species. B. pertussis and B.
Dimitri A Diavatopoulos, Craig A Cummings, Leo M Schouls, Mary M Brinig, David A Relman, Frits R Mooi   +5 more
doaj   +2 more sources