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Bordetella parapertussis, a close related species of B. pertussis, can also cause the disease named pertussis or whooping cough. The number of cases caused by this related pathogen has risen sustained in the last years. The widely used cellular (wP) or acellular (aP) pertussis vaccines have little or no efficacy against B. parapertussis.
Bottero, Daniela +7 more
openaire +3 more sources
Background In Dutch laboratories molecular detection of B. pertussis and B. parapertussis is commonly based on insertion sequences IS481 and IS1001, respectively. Both IS elements are more widely spread among Bordetella species. Both Bordetella holmesii,
Ossewaarde Jacobus M +3 more
doaj +1 more source
Acute pathogens such as Bordetella pertussis can cause severe disease but are ultimately cleared by the immune response. This has led to the accepted paradigm that convalescent immunity is optimal and therefore broadly accepted as the “gold standard ...
Monica C. Gestal +3 more
doaj +1 more source
In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to seven fluoroquinolones [PDF]
The in vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to seven fluoroquinolones were assessed by the agar dilution method. Ciprofloxacin and temafloxacin were the most active compounds (MIC for 90% of isolates tested [MIC90], 0.06 microgram/ml), while enoxacin and pefloxacin were the least active (MIC90, 0.5 microgram/ml ...
J E, Hoppe, C G, Simon
openaire +2 more sources
Evaluation of real-time PCR for diagnosis of Bordetella pertussis infection [PDF]
Background Nucleic acid amplification of the IS481 region by PCR is more sensitive than culture for detection and diagnosis of Bordetella pertussis but the assay has known cross-reactivity for Bordetella holmesii and its use as a routine diagnostic assay
Laina Knorr +3 more
core +1 more source
Pathogenicity and virulence of Bordetella pertussis and its adaptation to its strictly human host
The highly contagious whooping cough agent Bordetella pertussis has evolved as a human-restricted pathogen from a progenitor which also gave rise to Bordetella parapertussis and Bordetella bronchiseptica.
Thomas Belcher +4 more
doaj +1 more source
Natural History and Ecology of Interactions Between Bordetella Species and Amoeba
A variety of bacteria have evolved the ability to interact with environmental phagocytic predators such as amoebae, which may have facilitated their subsequent interactions with phagocytes in animal hosts.
Longhuan Ma +6 more
doaj +1 more source
isolates in Finland: Serotype and fimbrial expression [PDF]
Background Bordetella pertussis causes whooping cough or pertussis in humans. It produces several virulence factors, of which the fimbriae are considered adhesins and elicit immune responses in the host. B.
Eriikka Heikkinen +6 more
core +1 more source
Changes in the genomic content of circulating Bordetella pertussis strains isolated from the Netherlands, Sweden, Japan and Australia: adaptive evolution or drift? [PDF]
Background Bordetella pertussis is the causative agent of human whooping cough (pertussis) and is particularly severe in infants. Despite worldwide vaccinations, whooping cough remains a public health problem.
Audrey J King +4 more
core +1 more source
The recognition of bacterial lipopolysaccharide (LPS) by host Toll-like receptor (TLR)4 is a crucial step in developing protective immunity against several gram negative bacterial pathogens. Bordetella bronchiseptica and B.
Daniel N Wolfe +2 more
doaj +1 more source

