Results 41 to 50 of about 4,724 (213)

Outer membrane vesicles derived from Bordetella parapertussis as an acellular vaccine against Bordetella parapertussis and Bordetella pertussis infection

open access: yesVaccine, 2013
Bordetella parapertussis, a close related species of B. pertussis, can also cause the disease named pertussis or whooping cough. The number of cases caused by this related pathogen has risen sustained in the last years. The widely used cellular (wP) or acellular (aP) pertussis vaccines have little or no efficacy against B. parapertussis.
Bottero, Daniela   +7 more
openaire   +3 more sources

A real-time PCR assay with improved specificity for detection and discrimination of all clinically relevant Bordetella species by the presence and distribution of three Insertion Sequence elements

open access: yesBMC Research Notes, 2011
Background In Dutch laboratories molecular detection of B. pertussis and B. parapertussis is commonly based on insertion sequences IS481 and IS1001, respectively. Both IS elements are more widely spread among Bordetella species. Both Bordetella holmesii,
Ossewaarde Jacobus M   +3 more
doaj   +1 more source

Bbvac: A Live Vaccine Candidate That Provides Long-Lasting Anamnestic and Th17-Mediated Immunity against the Three Classical Bordetella spp.

open access: yesmSphere, 2022
Acute pathogens such as Bordetella pertussis can cause severe disease but are ultimately cleared by the immune response. This has led to the accepted paradigm that convalescent immunity is optimal and therefore broadly accepted as the “gold standard ...
Monica C. Gestal   +3 more
doaj   +1 more source

In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to seven fluoroquinolones [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1990
The in vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to seven fluoroquinolones were assessed by the agar dilution method. Ciprofloxacin and temafloxacin were the most active compounds (MIC for 90% of isolates tested [MIC90], 0.06 microgram/ml), while enoxacin and pefloxacin were the least active (MIC90, 0.5 microgram/ml ...
J E, Hoppe, C G, Simon
openaire   +2 more sources

Evaluation of real-time PCR for diagnosis of Bordetella pertussis infection [PDF]

open access: yes, 2006
Background Nucleic acid amplification of the IS481 region by PCR is more sensitive than culture for detection and diagnosis of Bordetella pertussis but the assay has known cross-reactivity for Bordetella holmesii and its use as a routine diagnostic assay
Laina Knorr   +3 more
core   +1 more source

Pathogenicity and virulence of Bordetella pertussis and its adaptation to its strictly human host

open access: yesVirulence, 2021
The highly contagious whooping cough agent Bordetella pertussis has evolved as a human-restricted pathogen from a progenitor which also gave rise to Bordetella parapertussis and Bordetella bronchiseptica.
Thomas Belcher   +4 more
doaj   +1 more source

Natural History and Ecology of Interactions Between Bordetella Species and Amoeba

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
A variety of bacteria have evolved the ability to interact with environmental phagocytic predators such as amoebae, which may have facilitated their subsequent interactions with phagocytes in animal hosts.
Longhuan Ma   +6 more
doaj   +1 more source

isolates in Finland: Serotype and fimbrial expression [PDF]

open access: yes, 2008
Background Bordetella pertussis causes whooping cough or pertussis in humans. It produces several virulence factors, of which the fimbriae are considered adhesins and elicit immune responses in the host. B.
Eriikka Heikkinen   +6 more
core   +1 more source

Changes in the genomic content of circulating Bordetella pertussis strains isolated from the Netherlands, Sweden, Japan and Australia: adaptive evolution or drift? [PDF]

open access: yes, 2010
Background Bordetella pertussis is the causative agent of human whooping cough (pertussis) and is particularly severe in infants. Despite worldwide vaccinations, whooping cough remains a public health problem.
Audrey J King   +4 more
core   +1 more source

Inefficient Toll-like receptor-4 stimulation enables Bordetella parapertussis to avoid host immunity.

open access: yesPLoS ONE, 2009
The recognition of bacterial lipopolysaccharide (LPS) by host Toll-like receptor (TLR)4 is a crucial step in developing protective immunity against several gram negative bacterial pathogens. Bordetella bronchiseptica and B.
Daniel N Wolfe   +2 more
doaj   +1 more source

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