Borna disease virus, a newly classified nonsegmented negative-strand RNA virus with international distribution, infects a broad range of warm-blooded animals from birds to primates.
Carolyn G. Hatalski +2 more
doaj +5 more sources
A Small Interfering RNA Cocktail Targeting the Nucleoprotein and Large Protein Genes Suppresses Borna Disease Virus Infection [PDF]
Recently, Borna disease virus (BoDV-1)-related fatal encephalitis human cases have been reported, which highlights the potential of BoDV-1 to cause fatal human diseases.
Da Teng +3 more
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Lethal Borna disease virus 1 infections of humans and animals – in-depth molecular epidemiology and phylogeography [PDF]
Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed shrew (Crocidura leucodon)
Arnt Ebinger +36 more
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Prominent Efficacy of Amantadine against Human Borna Disease Virus Infection In Vitro and In Vivo. Comment on Fink et al. Amantadine Inhibits SARS-CoV-2 In Vitro. Viruses 2021, 13, 539 [PDF]
Amantadine (1-amino-adamantane) is a versatile antiviral compound which has been licensed for decades against influenza viruses. During the Corona pandemic, its effect to inhibit SARS-CoV-2 in vitro has been investigated.
Liv Bode +3 more
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Borna disease (BD) is a sporadic neurologic disease of horses and sheep caused by mammalian Borna disease virus (BDV). Its unique epidemiological features include: limited occurrence in certain endemic regions of central Europe, yearly varying disease ...
Jolanta Kolodziejek +2 more
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Borna disease virus 2 maintains genomic polymorphisms by superinfection in persistently infected cells [PDF]
Mammalian orthobornaviruses, such as Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1, are zoonotic pathogens that cause fatal encephalitis in humans.
Takehiro Kanda +5 more
doaj +2 more sources
Nucleocytoplasmic Shuttling of Viral Proteins in Borna Disease Virus Infection
Nuclear import and export of viral RNA and proteins are critical to the replication cycle of viruses that replicate in the nucleus. Borna disease virus (BDV) is a nonsegmented, negative-strand RNA virus that belongs to the order Mononegavirales.
Tomoyuki Honda, Keizo Tomonaga
exaly +3 more sources
Increasing evidence of human infections by the neurotropic Borna disease virus 1 (BoDV-1) [PDF]
Michaela Cain, Hinh Ly
doaj +2 more sources
Human Borna disease virus 1 encephalitis shows marked pro-inflammatory biomarker and tissue immunoactivation during the course of disease [PDF]
Jessica Rauch +2 more
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Human Infections with Borna Disease Virus 1 (BoDV-1) Primarily Lead to Severe Encephalitis: Further Evidence from the Seroepidemiological BoSOT Study in an Endemic Region in Southern Germany [PDF]
Markus Bauswein +2 more
exaly +2 more sources

