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Borna Disease [PDF]

open access: yesEmerging Infectious Diseases, 1997
Borna disease virus, a newly classified nonsegmented negative-strand RNA virus with international distribution, infects a broad range of warm-blooded animals from birds to primates.
Carolyn G. Hatalski   +2 more
doaj   +5 more sources

A Small Interfering RNA Cocktail Targeting the Nucleoprotein and Large Protein Genes Suppresses Borna Disease Virus Infection [PDF]

open access: yesFrontiers in Microbiology, 2019
Recently, Borna disease virus (BoDV-1)-related fatal encephalitis human cases have been reported, which highlights the potential of BoDV-1 to cause fatal human diseases.
Da Teng   +3 more
doaj   +2 more sources

Lethal Borna disease virus 1 infections of humans and animals – in-depth molecular epidemiology and phylogeography [PDF]

open access: yesNature Communications
Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed shrew (Crocidura leucodon)
Arnt Ebinger   +36 more
doaj   +2 more sources

Prominent Efficacy of Amantadine against Human Borna Disease Virus Infection In Vitro and In Vivo. Comment on Fink et al. Amantadine Inhibits SARS-CoV-2 In Vitro. Viruses 2021, 13, 539 [PDF]

open access: yesViruses, 2022
Amantadine (1-amino-adamantane) is a versatile antiviral compound which has been licensed for decades against influenza viruses. During the Corona pandemic, its effect to inhibit SARS-CoV-2 in vitro has been investigated.
Liv Bode   +3 more
doaj   +2 more sources

The Bicolored White-Toothed Shrew Crocidura leucodon (HERMANN 1780) Is an Indigenous Host of Mammalian Borna Disease Virus

open access: yesPLoS ONE, 2014
Borna disease (BD) is a sporadic neurologic disease of horses and sheep caused by mammalian Borna disease virus (BDV). Its unique epidemiological features include: limited occurrence in certain endemic regions of central Europe, yearly varying disease ...
Jolanta Kolodziejek   +2 more
exaly   +3 more sources

Borna disease virus 2 maintains genomic polymorphisms by superinfection in persistently infected cells [PDF]

open access: yesnpj Viruses
Mammalian orthobornaviruses, such as Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1, are zoonotic pathogens that cause fatal encephalitis in humans.
Takehiro Kanda   +5 more
doaj   +2 more sources

Nucleocytoplasmic Shuttling of Viral Proteins in Borna Disease Virus Infection

open access: yesViruses, 2013
Nuclear import and export of viral RNA and proteins are critical to the replication cycle of viruses that replicate in the nucleus. Borna disease virus (BDV) is a nonsegmented, negative-strand RNA virus that belongs to the order Mononegavirales.
Tomoyuki Honda, Keizo Tomonaga
exaly   +3 more sources

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