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Borna disease virus and psychiatry
European Psychiatry, 2001 Borna disease virus (BDV), a noncytolytic neurotropic nonsegmented negative-stranded RNA virus with a wide geographic distribution, infects several vertebrate animal species and causes an immune-mediated central nervous system (CNS) disease with various manifestations, depending on both host and viral factors.
O, Taieb +3 more
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Borna disease virus and its role in the pathology of animals and humans
Regulatory Mechanisms in Biosystems, 2017 Infectious diseases that are caused by numerous pathogenic microorganisms – bacteria, viruses, protozoa or fungi – can be transmitted from patients or carriers to healthy people or animals.
A. O. Mikheev
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Borna disease virus 2 maintains genomic polymorphisms by superinfection in persistently infected cells [PDF]
npj VirusesMammalian orthobornaviruses, such as Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1, are zoonotic pathogens that cause fatal encephalitis in humans.
Takehiro Kanda +5 more
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Adaptation of Borna Disease Virus to the Mouse
Journal of General Virology, 1984 Borna disease virus has been adapted to the mouse, which required at least three passages in rat brains. Genetic specificity as studied with five inbred mouse strains was not evident. Newborn mice inoculated intracerebrally expressed antigen in neurons and remained persistently infected, with up to 10(7) infectious units per gram of brain tissue ...
M Kao, H Ludwig, G Gosztonyi
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Increasing evidence of human infections by the neurotropic Borna disease virus 1 (BoDV-1) [PDF]
Virulence, 2023 Michaela Cain, Hinh Ly
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Detection of Borna Disease Virus (BDV) in Patients with First Episode of Schizophrenia [PDF]
Iranian Journal of Psychiatry, 2016 Objective: Schizophrenia is a complex widespread neuropsychiatric disorder. This illness encompasses a complex debilitating mental disorder causing illusion, delusion, disturbed relationship, low motivation and decline of emotion.
Hasan Soltani +4 more
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The 24K protein of Borna disease virus
Journal of General Virology, 1992 Based on partial amino acid sequences obtained from tryptic peptides of the purified 24K antigen of Borna disease virus (BDV), we identified and sequenced four independent cDNA clones established from BDV-infected MDCK cells. Each of the clones encodes a polypeptide of 201 residues (Mr 22461) that differs considerably from an amino acid sequence ...
J, Thierer +9 more
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Reviews in Medical Virology, 2001 AbstractBorna disease virus (BDV) is unique amongst animal RNA viruses in its molecular biology and capacity to cause persistent, noncytolytic CNS‐infection in a wide variety of host species. Unlike other non‐segmented negative‐strand RNA animal viruses, BDV replicates in the nucleus of the host cell where splicing is employed for expression of a very ...
I, Jordan, W I, Lipkin
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Animal Models of CNS Viral Disease: Examples from Borna Disease Virus Models
Interdisciplinary Perspectives on Infectious Diseases, 2010 Borna disease (BD), caused by the neurotropic RNA virus, Borna Disease virus, is an affliction ranging from asymptomatic to fatal meningoencephalitis across naturally and experimentally infected warmblooded (mammalian and bird) species.
Marylou V. Solbrig
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Pathogenesis of Borna disease [PDF]
, 1993 Borna disease represents a unique model of a virus-induced immunological disease of the brain. Naturally occurring in horses and sheep, the mechanisms of pathogenesis have been studied in experimental animals, namely in the rat. Many investigations have revealed that the infection of the natural hosts principally follows the same pathogenic pathways as
L, Stitz, T, Bilzer, J A, Richt, R, Rott
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